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Journal of the Korean Academy of Rehabilitation Medicine 2008;32(6):637-643.
Correlation between Functional Evaluation Scales and Cognitive Evoked Potentials in Patients with Chronic Stroke.
Shin, A Young , Jang, In Sub , Ryu, Su Ra , Cho, Yun Mi , Han, Jae Young , Choi, In Sung , Kim, Jae Hyung , Lee, Sam Gyu
Department of Physical and Rehabilitation Medicine, Research Institute of Medical Sciences, Chonnam National University Medical School, Korea. LEE9299@hitel.net
만성 뇌졸중 환자에서 기능평가 척도와 인지유발전위와의 연관성
신아영, 장인섭, 류수라, 조윤미, 한재영, 최인성, 김재형, 이삼규
전남대학교 의과대학 재활의학교실 및 의과학연구소
Abstract
Objective
To investigate the correlation between functional evaluation scales and cognitive evoked potentials (CEPs) in chronic stroke patients.
Method
Ten chronic stroke patients with middle cerebral arterial infarction (age 53.6±15.7 years, 5 men, 5 women, duration 210.5±143.2 days) were recruited. Korean mini- mental status examination (K-MMSE) scores of the subjects were ranked between 15∼24 points and the grades of Rancho Los Amigos level of cognitive function of the subjects were VI or VII. They received physical therapy using neuro-developmental technique and cognitive rehabilitation twice a day, 5 times a week, for total 4 weeks. Before and after the treatment, cognitive function tests including K- MMSE, Loewenstein occupational therapy cognitive assessment (LOTCA) and motor-free visual perception test (MVPT) and functional ability tests including functional independence measure (FIM) and Korean version of National Institutes of Health stroke scale (K-NIHSS) were done and CEPs were recorded.
Results
The scores of K-MMSE, LOTCA, MVPT, FIM and K-NIHSS showed significant improvement, respectively (p<0.05). The P300 latencies significantly decreased from 420.2±34.8 msec to 391.5±36.4 msec (p<0.05). There were significant correlations between the percentage of change of P300 latencies and each percentage of change of K-MMSE, LOTCA and MVPT (r=0.863, p=0.001; r=0.745, p=0.013; r=0.806, p=0.005). There were significant correlations between the percentage of change of P300 latencies and each percentage of change of FIM and K-NIHSS (r=0.758, p=0.011; r=0.743, p=0.014).
Conclusion
The CEPs would be a useful method for reflecting the effect of neuro-cognitive rehabilitation treatment and predicting the functional recovery in chronic stroke patients. (J Korean Acad Rehab Med 2008; 32: 637-643)
Key Words: Cognitive evoked potentials, Stroke, Function, Outcome


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