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Journal of the Korean Academy of Rehabilitation Medicine 2008;32(6):637-643.
Correlation between Functional Evaluation Scales and Cognitive Evoked Potentials in Patients with Chronic Stroke.
Shin, A Young , Jang, In Sub , Ryu, Su Ra , Cho, Yun Mi , Han, Jae Young , Choi, In Sung , Kim, Jae Hyung , Lee, Sam Gyu
Department of Physical and Rehabilitation Medicine, Research Institute of Medical Sciences, Chonnam National University Medical School, Korea. LEE9299@hitel.net
만성 뇌졸중 환자에서 기능평가 척도와 인지유발전위와의 연관성
신아영, 장인섭, 류수라, 조윤미, 한재영, 최인성, 김재형, 이삼규
전남대학교 의과대학 재활의학교실 및 의과학연구소
To investigate the correlation between functional evaluation scales and cognitive evoked potentials (CEPs) in chronic stroke patients.
Ten chronic stroke patients with middle cerebral arterial infarction (age 53.6±15.7 years, 5 men, 5 women, duration 210.5±143.2 days) were recruited. Korean mini- mental status examination (K-MMSE) scores of the subjects were ranked between 15∼24 points and the grades of Rancho Los Amigos level of cognitive function of the subjects were VI or VII. They received physical therapy using neuro-developmental technique and cognitive rehabilitation twice a day, 5 times a week, for total 4 weeks. Before and after the treatment, cognitive function tests including K- MMSE, Loewenstein occupational therapy cognitive assessment (LOTCA) and motor-free visual perception test (MVPT) and functional ability tests including functional independence measure (FIM) and Korean version of National Institutes of Health stroke scale (K-NIHSS) were done and CEPs were recorded.
The scores of K-MMSE, LOTCA, MVPT, FIM and K-NIHSS showed significant improvement, respectively (p<0.05). The P300 latencies significantly decreased from 420.2±34.8 msec to 391.5±36.4 msec (p<0.05). There were significant correlations between the percentage of change of P300 latencies and each percentage of change of K-MMSE, LOTCA and MVPT (r=0.863, p=0.001; r=0.745, p=0.013; r=0.806, p=0.005). There were significant correlations between the percentage of change of P300 latencies and each percentage of change of FIM and K-NIHSS (r=0.758, p=0.011; r=0.743, p=0.014).
The CEPs would be a useful method for reflecting the effect of neuro-cognitive rehabilitation treatment and predicting the functional recovery in chronic stroke patients. (J Korean Acad Rehab Med 2008; 32: 637-643)
Key Words: Cognitive evoked potentials, Stroke, Function, Outcome


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