Cognitive evoked potentials, which are related to internally generated events, can be altered by psychological or cognitive differences.

In this study, we investigated the characteristic of amplitude and latency of P300 using t재 tone discrimination task in 21 patients with stroke compared to those of 44 control subjects.

The results were as follows.

1) The patients' average age was 57.67⁑6.25 years, and the average duration of stroke was 32.33⁑21.9 weeks.

2) In patients with stroke, the latency of cognitive evoked potentials (P300) was prolonged with statistical significance(P<0.001), but the amplitude of P300 was not significantly reduced than in the controls.

3) No significant difference in P300 latency and amplitude between male and female patients was found.

4) No significant difference in P300 latency and amplitude between cerebral infarcted and hemorrhegic patients was found.

In conclusion, this findings suggest that the latencies of P300 maybe useful clinical measures which can reflect cognitive dysfunction patients with stroke.