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Jung: Stroke Rehabilitation Fact Sheet in Korea
This article has been corrected. See Ann Rehabil Med. 2022 Apr 30; 46(2): 108.


With rapid aging, the number of stroke survivors with disabilities in Korea is increasing even if mortality is declining. Despite coordinated efforts for quality improvement of stroke rehabilitation in Korea, the statistics of stroke rehabilitation were not well reported. This review aimed to provide contemporary and comprehensive statistics and recent changes in stroke rehabilitation in Korea. The Clinical Practice Guideline for Stroke Rehabilitation in Korea was developed in 2009 and updated in 2012 and 2016. Additionally, the representative databases for stroke rehabilitation include the Korean Brain Rehabilitation Database and the Korean Stroke Cohort for functioning and rehabilitation. These nationwide databases provided current information on stroke rehabilitation. Among Korean stroke survivors, one in three had motor impairment, one in four had cognitive impairment, one in three had speech impairment, one in four was dependent in ambulation, one in six had swallowing difficulty, and one in four was dependent in activities in daily living at 5 years after stroke. Comprehensive inpatient rehabilitation following transfer to the department of rehabilitation medicine significantly decreased stroke-related mortality and long-term disability. This review provides an improved understanding of stroke rehabilitation and guidance to implement timely, coordinated, evidence-based stroke rehabilitation services to relieve the socioeconomic burden of stroke.


Stroke is the second-leading cause of death and the third-leading cause of death and disability combined based on the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) in 2019 [1]. Globally, the stroke incidence, stroke prevalence, deaths from stroke, and stroke-related disability-adjusted life-years (DALYs) increased by 70%, 85%, 43%, and 32%, respectively, from 1990 to 2019 [1,2].
In Korea, one of the most rapidly aging countries, the absolute number of incident strokes increased by 29.7% from 2014 to 2019 [3]. However, stroke mortality decreased by 12.8% from 2014 to 2019 due to better risk factor management and improved medical interventions [3] (Fig. 1). In Korea, stroke is the fourth leading cause of death [3].
A previous study reported a socioeconomic burden of stroke in Korea as high as 4,135.78 billion Korean won in 2017, which has been increasing continuously [4]. More than 250,000 people are disabled due to brain disorders in Korea [3] and this population has also aged as the general population. Moreover, the medical cost of disabilities due to brain disorders is one of the highest among the 15 disability categories in Korea [5] (Fig. 2). Therefore, increased numbers of stroke survivors may impose a greater socioeconomic burden on the Korean society.
In Korea, stroke survivors with severe stroke and severe disability tend to stay hospitalized longer and experience repeated admissions to multiple hospitals [6]. Therefore, functional enhancement by implementing efficient stroke rehabilitation is needed to reduce the direct medical costs associated with stroke. While many factors affect post-stroke recovery, timely provision of appropriate rehabilitation services is critical for better functional recovery.
Both socioeconomic factors and the medical characteristics of the disease affect the organization of and changes to rehabilitation services. The socioeconomic factors include healthcare and the insurance system, the structure of medical reimbursement, healthcare resources, accessibility of medical services, social awareness, and medical care utilization behaviors of that society. Therefore, improved implementation of healthcare policies for stroke survivors requires an understanding of the current situation of stroke rehabilitation in Korea. The present review aimed to provide contemporary and comprehensive statistics and recent trends regarding stroke rehabilitation in Korea.


Improvement in acute stroke rehabilitation

The Acute Stroke Quality Assessment Program (ASQAP) is an external audit that is used by the Health Insurance Review and Assessment Service (HIRA) in Korea to assess the quality of acute stroke care [7]. After the first assessment in 2005, the HIRA repeated stroke quality assessments in 2008, 2010, 2011, 2013, 2014, 2016, 2018, and 2021. The assessments include nine performance parameters and 15 monitoring parameters. The performance parameters include those related to early assessment for stroke rehabilitation and screening of swallowing function. The monitoring parameters include the provision of stroke unit care, early initiation of rehabilitation treatment, and functional outcome assessment at discharge. The ASQAP contributes to promoting the earlier initiation of stroke rehabilitation, improving the quality of acute stroke care, and reducing disparities among stroke hospitals in Korea.

Clinical practice guideline for stroke rehabilitation

Stroke rehabilitation specialists in Korea gathered and reviewed relevant literature to provide direction and standardization for the rehabilitation of acute, subacute, and chronic stroke in Korea. These efforts resulted in the development of the first edition of Clinical Practice Guideline (CPG) for Stroke Rehabilitation in Korea in 2009 [8]. These CPGs were updated in 2012 and 2016 as the second and third editions [9,10]. The CPGs for Stroke Rehabilitation in Korea provide evidence-based recommendations for higher-quality stroke rehabilitation, with timely, organized, and interprofessional care for the best predictable post-stroke recovery [9]. The development of these CPGs increases the likelihood of the delivery of a standard of care, with adequate resources and doses in comprehensive rehabilitation programs.

Nationwide database for stroke rehabilitation

Several nationwide databases for stroke rehabilitation exist in Korea. The Korean Brain Rehabilitation Database (KBRD) was developed in 2005 by the Korean Society of Neurorehabilitation (KSNR). The KBRD was an online system for the collection of nationwide demographic and clinical data from subjects with brain disorders including stroke, traumatic brain injury, and brain tumors [11].
The Korean Stroke Cohort for functioning and rehabilitation (KOSCO) is a large multicenter prospective cohort of people with acute first-ever stroke [2]. This cohort was constructed to prospectively investigate the long-term functional outcomes and quality of life issues arising in patients with first-ever stroke and to identify factors influencing residual disability and long-term quality of life [2].
The first KOSCO cohort enrolled 10,636 participants between August 2012 and December 2017 [2]. Among them, 7,858 subjects were longitudinally followed up for more than 60 months. The second cohort included 3,686 suBjects enrolled between January 2020 and December 2020. Among them, 2,431 participants have been followed up [12]. The inclusion criteria were as follows: (1) first-ever stroke (ischemic or hemorrhagic) with corresponding lesions on magnetic resonance imaging/angiography scan, (2) age ≥19 years, and (3) an understanding of the purpose of the study and consent to participate in the study. The exclusion criteria were as follows: transient ischemic attack and recurrent stroke [2].
In this review, most data on stroke rehabilitation were derived from the two aforementioned databases.

Stroke incidence, mortality, and recurrence in Korea

The number of people who visited the emergency room due to stroke in 2019, 120,584, was a 31.1% increase compared to that in 2012 [3]. The number of deaths from stroke decreased from 26,514 in 2010 to 21,586 in 2019 [3] (Fig. 1).
Based on the analysis of the first KOSCO cohort, the cumulative death rates of the first-ever stroke were 11.8% at 1 year, 15.4% at 2 years, 18.9% at 3 years, 22.2% at 4 years, and 25.2% at 5 years post-stroke [12]. The significant factors related to mortality in first-ever stroke were the type of stroke, sex, age, comorbidities, hypertension, pneumonia, transfer to the Department of Rehabilitation Medicine (RM transfer), initial stroke severity, initial motor function, and initial ambulatory capacity [12] (Table 1). Stroke patients with RM transfer were more likely to survive (p<0.05) (Fig. 3), while RM transfer and pneumonia were the only controllable factors related to post-stroke mortality [12].
The analysis of the first KOSCO cohort showed recurrence rates of first-ever stroke of 8.9% at 1 year, 10.9% at 2 years, 12.7% at 3 years, 14.3% at 4 years, and 15.5% at 5 years post-stroke. Moreover, ischemic and severe strokes were more likely to recur than hemorrhagic and mild stroke [12]. Within 1 year after first-ever non-cardioembolic ischemic stroke, 6.0% of patients experienced a recurrence [13]. The predictors of recurrence were age, functional impairment at discharge, and comorbidities [13].

Functional change during 5 years after first-ever stroke

The first KOSCO cohort was followed up for more than 60 months [12] (Fig. 4). At 6 months post-stroke, 48.3% of patients showed motor impairment, 31.1% showed cognitive impairment, 46.5% had speech impairment, 18.1% had swallowing impairment, and 34.6% showed ambulation impairment. The prevalence of post-stroke depression was 49.3% at 6 months. A total of 35.9% of stroke survivors remained dependent to some level in activities of daily living (ADLs) 6 months after stroke.
In each functional domain, significant improvement was observed up to 18 months after the first-ever stroke; however, functional deteriorations were observed in most domains starting in the third year. The functional decline at 3 years post-stroke was more evident in subjects who were ≥65 years, subjects with more severe motor impairment within the first year, subjects with diabetes, or subjects with atrial fibrillation.
At 5 years post-stroke, 38.6% of patients showed motor impairment, 24.8% showed cognitive impairment, 36.6% had speech impairment, 16.0% had swallowing impairment, and 25.8% showed impairment in ambulation. The prevalence of post-stroke depression was 34.2% at 6 months post-stroke. A total of 24.4% of patients remained dependent to some level in ADLs 5 years after stroke.
As independence in ADLs at 3 months post-stroke continues to affect independence in ADLs until 5 years after stroke (Table 2), improvement in functional independence through comprehensive rehabilitation should be facilitated from the early phase after stroke.

Recent changes in stroke characteristics and stroke rehabilitation

In the KOSCO study, the second cohort was developed in 2020, 5–8 years after the first cohort. Therefore, comparisons of the two cohorts provide information regarding recent changes in stroke and stroke rehabilitation in Korea [12].
We observed no significant difference in the stroke type between the two cohorts. However, the mean age at the first-ever stroke increased by 1.9 years from the first to second cohort (Fig. 5). The number of persons who experienced a first-ever stroke in their 80s increased from 12.3% to 18.1% (p<0.05).
The rates of admission to stroke units increased from 48.9% to 62.7% (p<0.05); similarly, the referral to inpatient rehabilitation increased from 75.1% to 85.7% (p<0.05). The mean interval between admission and referral of inpatient rehabilitation decreased from 2.7 to 2.1 days.
Among rehabilitation therapies, bedside physiotherapy was most often provided to patients in the first KOSCO cohort before RM transfer (Table 3). In contrast, gait training in the physical therapy room was the most frequent rehabilitation therapy provided to the second KOSCO cohort (Table 3). This change suggests the increasing prevalence of the early administration of comprehensive rehabilitation.
The rate of RM transfer increased from 16.5% to 19.7% (p<0.05). The number of days from stroke onset to RM transfer decreased from 16.8 days to 13.4 days (p<0.05). Considering a previous study of 5,212 patients from the KBRD, which reported a decrease in mean interval between stroke onset and RM transfer from 44 to 33 days between 2007 and 2011 [11], the delay incomprehensive inpatient rehabilitation has continuously shortened.
The mean length of stay (LOS) in the department of RM was 45 days in 2007 and decreased to 28 days in 2011 [11]. The mean LOS decreased from 32.8 days in the first KOSCO cohort to 25.7 days in the second KOSCO cohort (p<0.05).
The proportion of patients discharged from the department of RM increased from 16.4% to 18.7% (p<0.05). Among discharge destinations, a higher proportion of stroke survivors was discharged to rehabilitation-specialized hospitals in the second KOSCO cohort (19.4%) compared to the first KOSCO cohort (12.4%, p<0.05). However, this proportion was much lower than the 47.7% of patients who were discharged to another rehabilitation-specialized hospital between 2008 and 2009 [14]. Thus, more patients with stroke went home after comprehensive inpatient rehabilitation. The proportion of people discharged home also increased from 41.9% to 45.5% between the first and second KOSCO cohorts (p<0.05).
Functional status and quality of life at 3 months post-stroke improved significantly in the second cohort (p<0.05) and post-stroke depression was less prevalent in the second cohort compared to the first cohort (p<0.05).


This review focused on contemporary and comprehensive statistics and current changes in stroke rehabilitation in Korea. Despite its decreasing mortality, the socioeconomic burden of stroke has increased and will likely continue to do so without effective and efficient stroke rehabilitation strategies. Stroke rehabilitation is a comprehensive, multidisciplinary process with variable components, delivered by many professions as a continuum. Considering its regional and national specificity, knowledge of the current status of stroke rehabilitation is a prerequisite to maximizing its effectiveness and efficiency for better functional outcomes and reduced mortality. However, more nationwide database and research are necessary. This review and subsequent works will contribute to the inclusion in our society of future stroke survivors and their families, who will benefit from well-established stroke rehabilitation.


No potential conflict of interest relevant to this article was reported.


I thank the researchers of the Korean Brain Rehabilitation Database (KBRD) and the Korean Stroke Cohort for functioning and rehabilitation (KOSCO).

Fig. 1.
Stroke mortality in Korea (2010–2019).
Fig. 2.
Annual medical cost per person in 15 categories of disability in Korea (2018). Adapted from the National Rehabilitation Center [5]. KRW, Korean won.
Fig. 3.
Survival curve after first-ever stroke according to transfer to the Department of Rehabilitation Medicine. Adapted from the National Institute of Health [12].
Fig. 4.
Five-year post-stroke functional changes in the first cohort of the Korean Stroke Cohort for functioning and rehabilitation (KOSCO): (A) K-MBI (ADL), (B) FMA (motor recovery), (C) K-MMSE (cognition), (D) FAC (ambulation), (E) ASHA-NOMS (swallowing), (F) Short K-FAST (speech). Adapted from the National Institute of Health [12]. K-MBI, Korean version of Modified Barthel Index; ADL, activities of daily living; FMA, Fugl-Meyer Assessment; K-MMSE, Korean version of Mini-Mental State Examination; FAC, Functional Ambulation Category; ASHA-NOMS, Association National Outcome Measurement System Swallowing Scale; K-FAST, Korean version of Frenchay Aphasia Screening Test.
Fig. 5.
Comparison of age distributions for first-ever stroke between the first and second cohorts of the Korean Stroke Cohort for functioning and rehabilitation (KOSCO). Adapted from the National Institute of Health [12].
Table 1.
Multivariate analysis using Cox model for significant independent factors affecting mortality after firstever stroke
Factors Hazard ratio p-value
Stroke type (infarction) 0.637 <0.001*
Sex (female) 0.794 0.001*
Age (>65 yr) 4.045 <0.001*
Comorbidity (CCAS ≥8) 0.480 <0.001*
Hypertension 1.160 0.028*
Complication 1.066 0.414
Pneumonia 1.213 0.125
Transfer or not to rehabilitation medicine 0.498 <0.001*
NIHSS at 7 days
 Moderate 2.165 <0.001*
 Severe 4.595 <0.001*
FMA at 7 days (severe) 0.879 0.207
FAC at 7 days (severe) 2.067 <0.001*

Adapted from Kang SH, Choi YJ, Lee KH, Kim YH, Jang WH, Shin MA, et al. The Korean Stroke Cohort for Functioning and Rehabilitation (KOSCO). Public Health Wkly Rep 2018;11:1152-62.

NIHSS, National Institutes of Health Stroke Scale; CCAS, Combined Condition- and Age-related Score; FMA, Fugl-Meyer Assessment; FAC, Functional Ambulatory Categories.

* p<0.05.

Table 2.
Significant predictors for independence in activities in daily living up to 5 years post-stroke
Factors 6 mo after onset 1 yr after onset 2 yr after onset 3 yr after onset 5 yr after onset
Diabetes mellitus
Atrial fibrillation
Coronary artery disease
Comorbidities before onset
Degree of disability before onset
Cognitive function 3 mo before onset
Motor function 3 mo before onset
Ambulation 3 mo before onset
Swallowing 3 mo before onset
Speech 3 mo before onset
Activities of daily living

Adapted from the National Institute of Health [12].

Table 3.
Rehabilitation therapies provided to the subjects in the first and second cohorts of the KOSCO before transfer to rehabilitation medicine
KOSCO cohort (%)
First Second
Physical therapy
 Bed side PT 61.0 86.9
 NDT 37.8 76.7
 Mat/Gait 40.9 91.3
 Complex 6.2 4.9
 FES 20.8 52.7
 Tilt table 2.8 0
Occupational therapy
 Special 27.4 46.8
 Complex 11.2 25.7
 ADL 10.5 32.5
Speech therapy 3.2 10.1
Swallowing therapy
 Vital stimulation 1.2 1.4
 Oromotor 3.2 4.7
Cognitive therapy 0.5 1.3
Respiratory therapy 1.8 0.5

KOSCO, Korean Stroke Cohort for functioning and rehabilitation; NDT, neurodevelopmental treatment; ADL, activities of daily living.


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