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Journal of the Korean Academy of Rehabilitation Medicine 1996;20(1):25.
Effects of Serum Bilirubin on Brainstem Evoked Potentials in Full-term Neonates
Seong Eun Koh M.D., Jong Moon Kim M.D., Soo Young Lee M.D. , Soon Yeol Chong M.D.
Department of Rehabilitation Medicine, College of Medicine, Kon-Kuk University
빌리루빈 농도에 따른 신생아의 뇌간청각유발전위의 변화
고성은, 김종문, 이수영, 정순열
건국대학교 의과대학 재활의학교실

Brainstem evoked potentials(BSEP) in newborn infants are altered by elevated serum bilirubin levels and may be used as an indicator of bilirubin toxicity. The purpose of this study is to evaluate the effects of serum bilirubin on brainstem evoked potentials in full-term neonates. We examined altered responses of brainstem evoked potentials by studying 81 full erm neonates divided into three gruops: group 1(n=33), peak serum bilirubin(PB) level<5mg/dl; group2(n=22), 5mg/dl10mg/dl. The rate of appearance of peak waves reduced significantly in peak I, II, III, & V of group 2 and all peak waves of group 3 as compared with group 1, respectively. The increased serum bilirubin levels were associated with significant amplitude reduction of peak waves, but had no effect on absolute latencies and interpeak latencies. According to those results, we conclude that the increased serum bilirubin levels affect the amplitudes of the peak waves rather than the latencies or interpeak latencies of brainstem evoked potentials in full-term neonates.

Key Words: Brainstem evoked potentials(BSEP), Hyperbilirubinemia, Full-term neonate


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