J Korean Acad Rehabil Med Search


Journal of the Korean Academy of Rehabilitation Medicine 2000;24(2):179-184.
The Optimal Condition for Activation of Motor Cortex by Peripheral Electrical Stimulation in Rat.
Jang, Sung Ho , Ahn, Sang Ho
Department of Rehabilitation Medicine, Yeungnam University College of Medicine.
흰쥐의 대뇌피질 운동영역 활성화를 위한말초 전기자극의 적정 조건
장성호, 안상호
영남대학교 의과대학 재활의학과

To investigate the optimal condition for activation of motor cortex by electrical stimulation of forelimb in rat.

Eleven adult rats (Sprague-Dawley rat) were studied, each of which was anesthetized and craniotomized. While the electrical stinulation was given on the contralateral forelimb of the fixed rat at stereotaxic frame, the evoked potential (EP) was obtained at the motor cortex of rat brain. The conditions of electrical stimulation were changed with 5 kinds of frequencies (1, 3, 5, 10, 15 Hz), 4 kinds of stimulus intensities (1, 3, 5, 7 mA) and 3 kinds of pulse widths (100, 200, 300μsec).

The peak latencies of EPs in the motor cortex were significantly decreased and the amplitudes were significantly increased along with the decrement of stimulus frequency and the increment of stimulus intensity. The peak latencies and amplitudes of EPs were not significantly changed by stimulus pulse widths.

The motor cortex of rat was more activated with lower frequency and higher intensity regardless of pulse width in the given condition of electrical stimulation in this study. Key_words: 전기적 자극, 운동 피질, 유발전위, Electrical stimulation, Motor cortex, Evoked potential

Key Words: Electrical stimulation, Motor cortex, Evoked potential


Browse all articles >

Terms of Use   |   Privacy Polity
Editorial Office
Department of Rehabilitation Medicine, Seoul National University Hospital
101 Daehak-ro, Jongno-gu, Seoul, Korea
Tel: +82-10-8678-2671    Fax: +82-2-6072-5244    E-mail: edit@e-arm.org; edit.karm@gmail.com
Business Registration: 110-82-07460                

Copyright © 2024 by Korean Academy of Rehabilitation Medicine.

Developed in M2PI

Close layer