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Journal of the Korean Academy of Rehabilitation Medicine 2001;25(2):241-248.
Clinical Profile of Duchenne Muscular Dystrophy.
Moon, Jae Ho , Park, Yoon Ghil , Park, Jun Soo , Na, Young Moo , Kim, Yoon Jin , Kang, Seong Woong
1Department of Rehabilitation Medicine and Rehabilitation Institute of Muscular disease.
2Yonsei University College of Medicine.
3Department of Rehabilitation Medicine, Soonchunhyang University College of Medicine.
4Department of Rehabilitation Medicine, Inje University College of Medicine.
뒤시엔느형 근디스트로피 환자의 포괄적 임상 고찰
문재호, 박윤길, 박준수1, 나영무2, 김윤진, 강성웅
연세대학교 의과대학 재활의학교실 및 근육병재활연구소, 1순천향대학교 의과대학 재활의학교실 및 2인제대학교 의과대학 재활의학교실

To evaluate clinical features in general and possible complications in Duchenne muscular dystrophy (DMD) which could be used for comprehensive rehabilitation management.

One hundred and seventy-two patients with DMD were followed over 3 year period to provide clinical profile causing impairment and disability. We measured height, weight and manual muscle testing (MMT) when the patients visited the hospital. And we could measure pulmonary function, electrocardiogram (EKG), and intelligence quotient (IQ) test in cooporative patients.

The median height and weight of DMD boys were normally distributed before age 12, but during the second decade height was markedly reduced, and weight was no longer normally distributed. The MMT measurement showed loss of strength in a fairly linear fashion according to increasing age, and extensor of lower extremities were weaker than flexors showing typical contractures of legs. There was a direct relationship between pulmonary function and MMT scores of upper extremities. There was a high occurrence (40%) of abnormal EKG, but none of the patients had a history of cardiovascular complication. DMD children suffered wide spectrum of psychological disturbance such as somatic complaints, attention and emotional problems in addition to expected psychological problems due to chronic disease and its progression, and 50.9% of them were below average on the IQ test.

These data on DMD subjects provide clinicians with useful information regarding the prevalence and severity of measurable impairment at different stages of the disease.

Key Words: Duchenne muscular dystrophy, Complication, Contracture, Cardiovascular complication, Psychological disturbance


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