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Journal of the Korean Academy of Rehabilitation Medicine 2001;25(3):514-518.
H MR Spectroscopy on Parkinson's-like Syndrome Induced by Manganese Intoxication: A Case Report.
Kim, Chang Hwan , Kim, Myeong Ok , Jung, Han Young , Roh, Gill Ho , Lim, Myung Kwan
1Department of Rehabilitation Medicine, Inha University College of Medicine.
2Department of Radiology, Inha University College of Medicine.
망간 중독에 의한 파킨슨양 증후군에서의 1H MR Spectroscopy 소견 1례 ⁣증례 보고⁣
김창환, 김명옥, 정한영, 노길호, 임명관1
인하대학교 의과대학 재활의학교실, 1방사선과학교실

Manganese intoxificaton is a well-known cause of Parkinson's like syndrome.

We describe a 46-year-old man who had been occupationally exposed to manganese and report the case with hydrogen magnetic resonance spectroscopy (1H MRS). Ratios of N-acetyl-aspartate (NAA) to creatine were significantly reduced in basal ganglia regions compared to normal subjects. The level of NAA was decreased in basal ganglia regions may indicate neuronal dysfunction. 1H MRS can provide detailed information of brain damage, therefore the 1H MRS is very useful in diagnosis of manganese intoxification.

Key Words: Manganese, Parkinson's-like syndrome, Magnetic resonance imaging, Magnetic resonance spectroscopy


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