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Journal of the Korean Academy of Rehabilitation Medicine 1998;22(5):1141-1144.
Serotonin Syndrome in Traumatic Brain Injury Patient: A case report.
Song, Yangjoo , Park, Insun
Departmetn of Rehabilitation Medicine, Inje University College of Medicine.
외상성 뇌손상환자에서 발생된 세로토닌 증후군 ⁣증례 보고⁣
송양주, 박인선
인제대학교 의과대학 재활의학교실

We report a 47-year old traumatic brain injury male patient who was treated for the rigidity and tremor with sinemet (carbidopa⁢levodopa) and artane (trihexyphenidyl). He came to the emergency room ten days after the stopping of sinemet. Acute onset of increased obtunded, immobile, rigid, deep coma, and minimal response to a deep pain was presented. There was no evidence of the focal neurological signs. Over the next two days, he awoke with a normal mental status. His muscle tone become normal and he returned to home without residual medical problems or complications.

We report a serotonin syndrome in a traumatic brain injury patient who was treated with sinemet and artane, which resulted in a dysregulation of serotonin activity.

Key Words: Sinemet, Serotonin syndrome, Traumatic brain injury, Sinemet


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