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Case Report

Serotonin Syndrome in Traumatic Brain Injury Patient: A case report.

Song, Yangjoo , Park, Insun
Journal of the Korean Academy of Rehabilitation Medicine 1998;22(5):1141-1144.
Departmetn of Rehabilitation Medicine, Inje University College of Medicine.
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We report a 47-year old traumatic brain injury male patient who was treated for the rigidity and tremor with sinemet (carbidopa⁢levodopa) and artane (trihexyphenidyl). He came to the emergency room ten days after the stopping of sinemet. Acute onset of increased obtunded, immobile, rigid, deep coma, and minimal response to a deep pain was presented. There was no evidence of the focal neurological signs. Over the next two days, he awoke with a normal mental status. His muscle tone become normal and he returned to home without residual medical problems or complications.

We report a serotonin syndrome in a traumatic brain injury patient who was treated with sinemet and artane, which resulted in a dysregulation of serotonin activity.

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