The Correlation of Lean Body Mass with Muscle Function in Duchenne Muscular Dystrophy. |
Lee, Eui Jin , Kim, Yoon Jin , Song, Nam Kyu , Kim, Eun Hye , Lee, Sang Chul , Moon, Jae Ho , Min, Kyung Sook |
1Department of Rehabilitation Medicine, Yonsei University College of Medicine, Korea. chriseyes@hanmail.net 2Rehabilitation Institute of Muscular Disease, Yonsei University College of Medicine, Korea. 3Department of Physical Exercise, Kyonggi University, Korea. |
뒤시엔느형 근디스트로피에서 제지방 체중과 근력의 관계 |
이의진, 김윤진, 송남규, 김은혜, 이상철, 문재호, 민경숙1 |
연세대학교 의과대학 재활의학교실 및 근육병 재활연구소, 1경기대학교 체육학과 |
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Abstract |
Objective To evaluate the relationship between the lean body mass and muscle function in patients with Duchenne muscular dystrophy (DMD). Method The subjects were thirty two DMD patients and an age-matched twelve healthy control volunteers. The DMD patients were divided into two groups; ambulatory and non- ambulatory groups. The body composition with dual energy X-ray absorptiometry (DEXA), body mass index (BMI) and functional state of all subjects were measured.
Results There was no significant difference in BMI among all groups. The non-ambulatory DMD group was siginificantly higher in total body fat (%) compared with other two groups (p<0.05). The mean lean body mass (%) for upper extrem ities did not show the significant difference; however, for lower extremities, there was a significantly lower in DMD groups (p<0.05). These findings were corresponded with low muscle functional state for lower extremities in DMD groups.
Conclusion There was a significant correlation between muscle function and the percentage of mean lean body mass. The assessment of lean body mass by DEXA provides more accurate and reliable information about the muscle function in DMD.
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Key Words:
Lean body mass, Muscle, Function, Duchenne muscular dystrophy, Dual |
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