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Journal of the Korean Academy of Rehabilitation Medicine 2004;28(3):281-287.
Influence of Beta Blocker on Cardiac Rehabilitation Program.
Shin, Ji Cheol , Kim, Chul , Bang, In Keol , Park, Eun Suk , Paik, Kwang Se , Ahn, Jae Ki , Kim, Yong Jin , Kim, Young Joo
1Department of Rehabilitation Medicine and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Korea.
2Department of Physiology, Yonsei University College of Medicine, Korea.
3Department of Rehabilitation Medicine, Inje University College of Medicine, Korea. bangik@sanggyepaik.ac.kr
베타 차단제가 심장재활 프로그램에 미치는 영향
신지철, 김철2, 방인걸2, 박은숙, 백광세1, 안재기2, 김용진2, 김영주2
연세대학교 의과대학 재활의학교실, 재활의학연구소 및 1생리학교실, 2인제대학교 의과대학 상계백병원 재활의학교실
The purpose of this study was to evaluate the beta blocker effect on excercise ability and hemodynamics after cardiac rehabilitation program (CRP).
Thirty-two patients with coronary artery disease were divided into two groups: 16 patients in the beta blocker group and 16 patients in the control group. CRP with aerobic exercise was done for 6 weeks. Before and after CRP, a symptom limited graded exercise test was done.
The maximal exercise time and the maximal oxygen uptake were significantly higher, and the percentage of maximal oxygen uptake and the rating of perceived exertion were significantly lower after CRP as compared to those parameters before CRP in both groups (p<0.05). There were no significant differences in above parameters between the beta blocker and control groups (p>0.05). The submaximal heart rate and submaximal rate pressure product (RPP) were significantly lower after CRP as compared to those before CRP in both groups (p<0.05). After CRP, the maximal heart rate and the submaximal RPP were significantly lower in the beta blocker group than in control (p<0.05).
A beta blocker can be widely used in CRP without having a negative effect on exercise capacity in the patients with coronary artery disease. (J Korean Acad Rehab Med 2004; 28: 281-287)
Key Words: Beta blocker, Cardiac rehabilitation program, Exercise response


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