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Journal of the Korean Academy of Rehabilitation Medicine 2005;29(6):640-646.
Immediate and Long-term Effect of Exercise on Heart Rate Variability in Coronary Artery Disease.
Kim, Chul , Bang, In Keol , Kim, Young Joo , Lee, Byoung Kwon , Byun, Young Sup , Ahn, Jae Ki , So, Mu Cheol , Jung, In Tak
1Department of Rehabilitation Medicine, Inje University College of Medicine, Korea. bangik@sanggyepaik.ac.kr
2Department of Internal Medicine, Inje University College of Medicine, Korea.
관상동맥질환에서 심박변동에 대한 운동의 장단기간 영향
김철, 방인걸, 김영주, 이병권1, 변영섭1, 안재기, 소무철, 정인탁
인제대학교 의과대학 재활의학교실, 1내과학교실
Abstract
Objective
To evaluate the dynamics of autonomic nervous activity at rest and immediately after maximum exercise using heart rate variability (HRV) in coronary artery disease (CAD) and to assess the long-term effect of exercise.
Method
Time and frequency domain of HRV was measured in 18 normal subjects, 37 CAD patients with percutaneous transluminal angioplasty and 10 CAD patients with coronary artery bypass graft at rest and 1 hour after peak graded treadmill exercise. Nineteen CAD patients were exercised with moderate intensity during 4 month and HRV was measured.
Results
At rest, the standard deviation of the NN interval (SDNN) and low frequency was significantly lower in bothCAD groups than in normal subjects. At recovery stage after maximum exercise, low frequency and low frequency/high frequency ratio was significantly lower in both CAD groups than in normal subjects. SDNN at recovery stage in normal subjects remained significantly below the baseline. There was no significant change in HRV after long-term exercise even though maximum oxygen uptake had improved.
Conclusion
This study demonstrated the reduced control of autonomic nervous activity in CAD patients at rest and immediately after peak exercise. There was no change in HRV after long-term exercise. (J Korean Acad Rehab Med 2005; 29: 640-646)
Key Words: Heart rate variability, Exercise, Coronary artery disease


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