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Journal of the Korean Academy of Rehabilitation Medicine 1977;1(2):3.
The Metabolism of Calcium in Patients with Spinal Cord Injuries
Kyoung Hee Kim, M.D., Chung Hie Oh, M.D., Hong Keun Lee, M.D.
Department of Rehabilitation Medicine, College of Medicine, Korea University, Seoul, Korea
척수손상환자의 칼슘대사
김경희, 오정희, 이홍건
고려대학교 의과대학 재활의학과교실

Spinal cord injuries produce a negative calcium balance that after results in osteoporosis, renal calculi, ectopic ossification, hypercalcemia and hypercalciuria. Urinary stone formation is the most frequent complication in the cord injured patient and it is particulary troublesome in the first 2 years of illness.

Increased urinary excretion of calcium increases the tendency for these minerals to precipitate out in the urinary tract and intercurrent infection provides a further stimulus to calculus formation.

The purpose of this study was to examine the variation of calcium metabolism with urinary calcium excretion and the serum calcium level and the relationship between the length of time after injury, cord levels and weight bearing on long bones.

The total number of patients in this study was 21.8 quadriplegia and 13 paraplegia, and age ranged from 16 to 60 years.

The following results were obtained:

1. Within days after onset, calcium level of 24 hours urine began to increase and remained until 1 year after injury, then reduced slowly to normal value by one and half year.

2. No significant variation was noted in serum calcium level throughout the observed duration of 2 years.

3. The mean of 24 hours urine calcium was 243.14 mg/24 hr in cervical, 218.72 mg/hr in thoracic and 196.10 mg/24 hr in lumbar cord lesion, respectively. But no significant correlation was found between the injured levels.

4. No significant correlation was found between urinary calcium level and weight bearing on long bone.

Key Words: Spinal cord injury, Calcium metabolism, Urinary calcium excretion, Serum calcium level, Weight bearing


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