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Journal of the Korean Academy of Rehabilitation Medicine 2000;24(6):1207-1212.
Acute Motor Axonal Neuropathy Associated with Anti-GM1 Antibody: A case report.
Kim, Hye Won , Ko, Young Jin , Kim, Kyong Hwa , Kim, Il Su , Ryu, Keun Hyeung
Department of Rehabilitation Medicine, College of Medicine, The Catholic University of Korea.
Anti-GM1 Antibody와 연관된 급성 운동신경 축삭 신경병증 ⁣증례 보고⁣
김혜원, 고영진, 김경화, 김일수, 류근형
가톨릭대학교 의과대학 재활의학교실

Guillain-Barre syndrme (GBS) has several subtypes that are divided by clinical, electro- physiological, and pathological findings. A novel form of GBS, that is termed acute motor axonal neuropathy (AMAN), is characterized by the selective involvement of motor fibers, and is associated with anti-GM1 antibodies.

A 8-year-old male patient were developed ascending, symmetrical paralysis, and areflexia, but no sensory disturbance. Elevated titers of serum IgG anti-GM1 antibodies were detected. His thoracolumbar spine magnetic resonance imaging (MRI) revealed thickening of cauda equina and enhancement of anterior nerve roots of T12-L1 spinal level after Gd-DTPA infusion. Electrophysiological diagnosis was acute motor axonal neuropathy (AMAN). We report this case with review of the literature.

Key Words: Acute motor axonal neuropathy (AMAN), Anti-GM1 antibodies


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