J Korean Acad Rehabil Med Search


Journal of the Korean Academy of Rehabilitation Medicine 2001;25(3):466-473.
Effect of Therapeutic Exercise according to Degree of Injury in Sciatic Nerve Damaged Rat.
Kim, Myeong Ok , Yoon, Joon Shik , Kwak, Jai Ryeung , Choi, Hyun Chul , Roh, Gill Ho , Kim, Sei Joo
1Department of Rehabilitation Medicine, Inha University College of Medicine.
2Department of Rehabilitation Medicine, Korea University College of Medicine.
좌골신경손상 유발 백서에서 손상정도에 따른 운동치료 효과
김명옥, 윤준식, 곽재륭, 최현철, 노길호, 김세주1
인하대학교 의과대학 재활의학교실, 1고려대학교 의과대학 재활의학교실

To investigate the effects of treadmill running and swimming exercise for the functional and electrophysiological recovery in rats with sciatic nerve damage, and to evaluate the patterns of recovery according to various degree of intensity and duration of injury.

Sixty male Sprague-Dawley rats (200∼250 g) were used, and divided into the control and the experimental groups. Crushing injuries to the sciatic nerve at the sciatic notch was manipulated using a hemostatic forcep, treadmill and swimming exercise programs were performed for 30 minutes on a daily basis, 5 days a week during the 4 week period. The experimental group was divided into 2 sub-groups in correlation with the intensity of injury, and into 5 and 30 seconds group in correlation with the duration of injury. The test results were analysed by sciatic nerve functional index (SFI) that was obtained through walking tract analysis, and by the amplitude of compound muscle action potentials in calf muscles through the sciatic motor nerve conduction study.

1) After 4 weeks following sciatic nerve injuries, the SFI were ⁣21.8⁑10.8, ⁣23.1⁑7.0, ⁣32.5⁑9.1 in treadmill, swimming, and control groups, respectively. Treadmill and swimming groups showed markedly improved function compared to the control group. Amplitudes of sciatic nerve compound muscle action potentials in calf muscle were 21.2⁑6.5, 15.9⁑5.8, 12.5⁑2.0 mV in treadmill, swimming, and control groups respectively, and revealed marked electrophysiological improvement in treadmill group. 2) The results concerning the intensity and the duration of injury, nerve recovery patterns showed the most significant improvement in the first degree-5 seconds group in both treadmill and swimming exercise programs.

These findings suggest that the treadmill and swimming exercises have significantly better effect in the regeneration of damaged sciatic nerve than that of control, and the intensity of injury was a more important factor in the recovery of nerves compared to the duration of injury.

Key Words: Sciatic nerve damage, Rat, Therapeutic exercise, Degree of injury


Browse all articles >

Terms of Use   |   Privacy Polity
Editorial Office
Department of Rehabilitation Medicine, Seoul National University Hospital
101 Daehak-ro, Jongno-gu, Seoul, Korea
Tel: +82-10-8678-2671    Fax: +82-2-6072-5244    E-mail: edit@e-arm.org; edit.karm@gmail.com
Business Registration: 110-82-07460                

Copyright © 2024 by Korean Academy of Rehabilitation Medicine.

Developed in M2PI

Close layer