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Journal of the Korean Academy of Rehabilitation Medicine 2001;25(5):803-811.
Functional Evaluation of Autonomic Nervous System in Patients with Chronic Renal Failure.
Kim, Sang Kyu , Choi, Yang Muk , Hwang, Eo Seong , Kang, Jeon Wan
Department of Rehabilitation Medicine, College of Medicine, Chungbuk National University.
만성 신부전 환자의 자율신경계 기능평가
김상규, 최양묵, 황어성, 강전완
충북대학교 의과대학 재활의학교실

To evaluate the autonomic nervous system function in chronic renal failure patients compared to normal control and to assess the effect of dialysis method and underlying diseases such as diabetes mellitus and hypertension, on autonomic nervous system function in chronic renal failure patients.

We checked palm and sole skin temperature with digital thermometer, sympathetic skin responses and heart rate variability in chronic renal failure patients (77 persons) and normal control group (77 persons).

The amplitude of sympathetic skin response (SSR) and heart rate variability (RRIV) of patients group showed statistically significant difference compared to control group (p<0.05). The diabetic patient group with chronic renal failure showed prolonged latency of SSR in sole but significant differences were shown in amplitude and RRIV (p<0.05). The hypertensive group with chronic renal failure showed prolonged latency of SSR in both palm and sole (p<0.05) but the amplitude and RRIV of those didn,t show statistical difference (p>0.05). CRF without diabetes mellitus and hypertension showed significant difference on amplitude of SSR and RRIV (p<0.05) but autonomic nervous system function tests showed no difference (p>0.05) between hemodialysis and peritoneal dialysis groups.

SSR test and RRIV could be valuable measure to evaluate autonomic nervous system functions in the patients with chronic renal failure.

Key Words: Autonomic nervous system, Heart rate variability, Sympathetic skin response, Chronic renal failure


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