Both hypothyroidism and hyperthyroidism can display signs and symptoms of neuromuscular dysfunction overshadowed by primary disease. Whatever the mechanism by which the thyroid affects muscles and nerves, prompt diagnosis and restoration of normal thyroid function leads to resolution of most neuromuscular symptoms. Therefore patients with thyroid dysfunction should be questioned for musculoske-letal complaints and referred to a specialist if necessary. Thyroid disorders should be considered as one of the causes in patients presenting musculoskeletal manifestation. We described four patients with thyroid disorders who presented with musculoskeletal manifestations. (J Korean Acad Rehab Med 2005; 29: 681-685)
