J Korean Acad Rehabil Med Search


Journal of the Korean Academy of Rehabilitation Medicine 2007;31(6):677-682.
Clinical Implication of Sniff Nasal Inspiratory Pressure in Patients with Amyotrophic Lateral Sclerosis.
Kim, Wan , Kang, Seong Woong , Lee, Sang Chul , Lee, Soo Hyun , Kim, Dong Soo
1Department of Rehabilitation Medicine and Rehabilitation Institute of Muscular Disease, Yonsei University College of Medicine, Korea.
2Department of Physical Medicine and Rehabilitation, Myongji Hospital, Kwandong University College of Medicine, Korea.
3Department of Rehabilitation Medicine, Yongdong Severance Hospital, Korea. kswoong@yumc.yonsei.ac.kr
근위축성 측삭 경화증 환자에서 Sniff Nasal Inspiratory Pressure의 임상적 의의
김완, 강성웅, 이상철1, 이수현2, 김동수
연세대학교 의과대학 재활의학교실 및 근육병 재활연구소, 1관동대학교 의과대학 명지병원 재활의학교실, 2영동세브란스병원 재활의학과
To evaluate sniff nasal inspiratory pressure (SNIP) in patients with amyotrophic lateral sclerosis (ALS), to analyse the relationship between SNIP and other pulmonary function test and to verify the usefulness of SNIP in patients with ALS.
Twenty-eight patients with ALS able to follow command were studied. SNIP and maximal inspiratory pressure (MIP) were measured using respiratory pressure meter in sitting position. Forced vital capacity (FVC) and peak cough flow (PCF) were evaluated using spirometer and peak flow meter respectively. The relationship between SNIP and other pulmonary function parameters were analysed.
The mean value of SNIP was -20.7 cmH2O (21.7% predicted) and the mean value of MIP was -16.3 cmH2O (8.0% predicted). SNIP correlated with MIP (r=0.776, p= 0.000). When expressed absolute value, SNIP was higher than MIP in twenty-one of the twenty-eight patients with ALS. Difference of SNIP and MIP was 4.4 cmH2O and it was statistically significant (p=0.001). SNIP and MIP correlated with FVC. SNIP and MIP correlated with PCF as well.
SNIP in patients with ALS is useful method to assess inspiratory muscle strength in addition to MIP. (J Korean Acad Rehab Med 2007; 31: 677-682)
Key Words: Amyotrophic lateral sclerosis, Sniff nasal inspiratory pressure, Pulmonary function test, Respiratory muscle strength


Browse all articles >

Terms of Use   |   Privacy Polity
Editorial Office
Department of Rehabilitation Medicine, Seoul National University Hospital
101 Daehak-ro, Jongno-gu, Seoul, Korea
Tel: +82-10-8678-2671    Fax: +82-2-6072-5244    E-mail: edit@e-arm.org; edit.karm@gmail.com
Business Registration: 110-82-07460                

Copyright © 2024 by Korean Academy of Rehabilitation Medicine.

Developed in M2PI

Close layer