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Journal of the Korean Academy of Rehabilitation Medicine 2008;32(3):285-288.
The Correlation between Post-stroke Depression and Lesion Location.
Kim, Jun Yeon , Kim, Tae Gun , Noh, Jae Hyun , Kim, Dong Hyup , Kim, Chul Hyun , Lee, Yang Soo , Jung, Tae Du
1Department of Rehabilitation Medicine, Kyungpook National University College of Medicine, Korea. teeed0522@naver.com
2Department of Rehabilitation Medicine, Daegu Fatima Hospital, Korea.
뇌졸중 후 발생한 우울증과 뇌 병변 위치와의 연관성
김준연, 김태건1, 노재현, 김동협, 김철현, 이양수, 정태두
경북대학교 의과대학 재활의학교실, 1대구파티마병원 재활의학과
To localize lesions which correlate with depression after stroke.
This study was performed in 98 stroke patients who admitted at two hospitals in Daegu in 2006. Lesions on magnetic resonance imaging were reviewed by same neuroradiologist and depression was diagnosed by same phychiatrist using DSM-III-R and ICD-10 criteria. We tried to find the correlation between the lesion location and depression.
Depression was not related to age, sex, dominant hemisphere, underlying disease (HTN, DM, heart disease), and many lesions of interest of brain. Lesions in prefrontal area, limbic lobe, cingulate gyrus, post white matter and frontal lobe correlated significantly with depression.
We found that there was a strong correlation between post stroke depression and the pathologic lesion which is frontal-subcortical circuit except basal ganglion and thalamus. (J Korean Acad Rehab Med 2008; 32: 285-288)
Key Words: Stroke, Depression, Lesion location


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