Change to Current Perception and Pain Tolerance Thresholdsfollowing Repetitive Transcranial Magnetic Stimulation.

, Sohn, Min Kyun; , Cho, Kang Hee; , Jee, Sung Ju; , Lee, Tae Sung

Original Article

Journal of the Korean Academy of Rehabilitation Medicine 2008;32(5):506-511.

Sohn, Min Kyun , Cho, Kang Hee , Jee, Sung Ju , Lee, Tae Sung

Department of Rehabilitation Medicine, College of Medicine, Chungnam National University, Korea. ltsssss@cnuh.co.kr

반복경두부자기자극에 의한 전류인지역치 및 통증내성역치의 변화

손민균, 조강희, 지성주, 이태성

충남대학교 의과대학 재활의학교실

Abstract

Objective
To investigate the effect of high-frequency repetitive transcranial magnetic stimulation (rTMS) over the primary motor cortex on sensory and pain perception.
Method
We measured the current perception threshold and the pain tolerance threshold with Neurometer^Ⱂ CPT/C in 14 healthy subjects (eleven males and three females, mean age: 25.0 years). Threshold testing was evaluated prior to, immediately after, 30 min after and 60 min after rTMS. The stimulation parameters were a frequency of 10 Hz and a field intensity of 100% of the active motor thresholds. Stimuli were provided in trains of 100 pulses, followed by a 50s rest period, 10 trains were applied in the session, resulting in 1,000 pulses in total.
Results
The current perception thresholds of 5, 250, 2,000 Hz were significantly increased immediately, 30 min after rTMS (p＜0.05) and no effects at all were noticed after sham rTMS. The pain tolerance thresholds of 5, 250 Hz were significantly increased immediately, 30 min after rTMS and the pain tolerance threshold of 2,000 Hz were significantly increased immediately, 30 min, 60 min after rTMS (p＜ 0.05). No effects at all were noticed after sham rTMS.
Conclusion
After high frequency rTMS over the primary motor cortex, we found that the current perception thresholds and the pain tolerance thresholds of 5, 250, 2,000 Hz were significantly increased. (J Korean Acad Rehab Med 2008; 32: 506-511)

Key Words: rTMS, Current perception thresholds, Pain tolerance thresholds