Persistent Autonomic Dysfunction in Guillain-Barre Syndrome: A case report.

, Lee, Sang Jee; , Choi, Eun Suk; , Jung, Sung Hee; , Cho, Ye Rim; , Han, Zee A; , Yu, In Hee

Case Report

Journal of the Korean Academy of Rehabilitation Medicine 2008;32(5):586-590.

Lee, Sang Jee , Choi, Eun Suk , Jung, Sung Hee , Cho, Ye Rim , Han, Zee A , Yu, In Hee

Department of Rehabilitation Medicine, College of Medicine, The Catholic University of Korea, Korea. hi271@naver.com

길랑-바레 증후군 환자에서 지속된 자율신경계 기능 이상 -증례 보고-

이상지, 최은석, 정성희, 조예림, 한지아, 유인희

가톨릭대학교 의과대학 재활의학교실

Abstract

Autonomic dysfunction is a common manifestation in Guillain-Barre syndrome (GBS), but it rarely persists. We report a case involving a 22-year-old man who presented with glove-and-stocking type sensory loss, symmetric weakness, urinary distension, orthostatic hypotension, decreased perspiration, and the syndrome of inappropriate secretion of antidiuretic hormone. He was subsequently diagnosed as having GBS with autonomic failure that persisted for more than six months, despite regaining muscle strength. Orthostatic hypotension progressively improved after rehabilitation and administration of midodrine and fludrocortisone. Extensive evaluation and management should be performed in patients with GBS because severe autonomic dysfunction is a major source of disability. (J Korean Acad Rehab Med 2008; 32: 586-590)

Key Words: Autonomic dysfunction, Orthostatic hypotension, Guillain-Barre syndrome