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Journal of the Korean Academy of Rehabilitation Medicine 2010;34(2):174-178.
The Influence of Depressive Symptoms on Cognitive and Functional Recovery in Chronic Stroke Patients.
Yoon, Tae Sang , Kwon, Bum Sun , Park, Jin Woo , Ryu, Ki Hyung , Lee, Ho Jun , Park, Sung Jun , Kim, Dae Hwan , Park, Nyo Kyung
Department of Physical Medicine & Rehabilitation, College of Medicine, Dongguk University, Korea. bskwon@duih.org
만성 뇌졸중 환자의 우울증상이 인지기능 및 기능적 회복에 미치는 영향
윤태상, 권범선, 박진우, 류기형, 이호준, 박성준, 김대환, 박여경
동국대학교 의과대학 재활의학교실
Abstract
Objective
To investigate the influence of depressive symptoms on cognitive and functional recovery in chronic stroke patients.
Method
Seventy-four chronic stroke patients were included. They had inpatient rehabilitation program for 2 months. Depressive symptoms were evaluated with the Beck depression inventory (BDI), cognitive functions by the Korean mini-mental status examination (MMSE-K) and functional status by the modified Barthel index (MBI) before and after the rehabilitation. We investigated whether the improvement of depressive symptoms after rehabilitation had influenced the cognitive and functional recovery, by comparing the changes of MMSE-K and MBI in patients with depressive symptoms.
Results
Before inpatient rehabilitation program, patients with depressive symptoms had low scores of MMSE-K and MBI compared to those without. While patients with depressive symptoms had significant improvement of MMSE- K after rehabilitation (p<0.05), those without did not. Both groups with and without depressive symptoms had significant improvement of MBI after rehabilitation, but the changes of MBI were not different significantly. Among patients with depressive symptoms at admission, those who showed improved depression after rehabilitation had the significant improvement of MMSE-K after rehabilitation (p<0.05), but those with sustained depressive symptoms did not.
Conclusion
Post-stroke depressive symptoms may influence on cognitive function. However, post-stroke depressive symptoms did not have any effect on functional recovery. (J Korean Acad Rehab Med 2010; 34: 174-178)
Key Words: Post-stroke depression, Cognition, ADL, Recovery


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