Comparison of Effects of Repetitive Transcranial Magnetic Stimulation with High- or Low-frequency on Visuospatial Neglect in Stroke Patients.

, Kim, Ji Sung; , Kim, Jong Chan; , Shin, Sung Hun; , Kim, Yong Kyun

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Original Article

Journal of the Korean Academy of Rehabilitation Medicine 2010;34(4):397-402.

Comparison of Effects of Repetitive Transcranial Magnetic Stimulation with High- or Low-frequency on Visuospatial Neglect in Stroke Patients.

Kim, Ji Sung , Kim, Jong Chan , Shin, Sung Hun , Kim, Yong Kyun

Department of Physical Medicine and Rehabilitation, Kwandong University College of Medicine, Korea. ykkim@kwandong.ac.kr

뇌졸중 환자에서 반복 경두개 자기자극이 편측 공간무시에 미치는 효과

김지성, 김종찬, 신성헌, 김용균

관동대학교 의과대학 재활의학교실

Abstract

Objective
To compare the effect of repetitive transcranial magnetic stimulation (rTMS) applied over the right or left parietal cortex with high- or low-frequency on visuospatial neglect in stroke patients.
Method
Nineteen stroke subjects (10 males, 9 females) were enrolled. All subjects received 1,200 real rTMS over left parietal cortex at an intensity of 90% of motor thresholds with 1 Hz, sham rTMS over right parietal cortex with 20 Hz and real rTMS over right parietal cortex at same intensity with 20 Hz under randomized cross over design. To compare the effects of different rTMS protocols, letter cancellation test, line bisection test (near, far) and Ota's task were administered before and after rTMS.
Results
Low frequency rTMS over left parietal cortex, compared with sham stimulation, significantly improve visuospatial neglect in Ota's task (p＜0.05).
Conclusion
As low frequency rTMS over left parietal cortex showed beneficial effects on visuospatial neglect, low frequency rTMS can be used as a treatment modality for patients suffering from visuospatial neglect after stroke. (J Korean Acad Rehab Med 2010; 34: 397-402)

Key Words: Repetitive transcranial magnetic stimulation, Visuospatial neglect, Stroke

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