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Journal of the Korean Academy of Rehabilitation Medicine 1996;20(1):35.
Clinical Significance of Blink Reflex in Neonates
Jong Moon Kim, M.D., Sang Hyun Kim, M.D. , Soon Yeol Chong, M.D.
Department of Rehabilitation Medicine, College of Medicine, Kon-Kuk University
신생아에서 순목반사의 임상적 의의에 관한 연구
김종문, 김상현, 정순열
건국대학교 의과대학 재활의학교실

The blink reflex is used for evaluation of trigeminal and facial nerves, and brainstem reflex through its pathway. The purpose of this study is to establish the normal values in healthy Korean neonates and to evaluate changes of blink reflex by hyperbilirubinemia and/or brain lesions in sick neonate. The study included 50 full-term neonates divided control(n=21) and patient group(n=29). The patient group is divided as follows: Group I(n=15): normal serum bilirubin(<10mg/dl) with brain lesion, Group II(n=7): high serum bilirubin(≥10mg/dl) without brain lesion and Group III(n=7): high serum bilirubin(≥10mg/dl) with brain lesion.

R1 was always obtained, its latency is 12.24±0.76msec, and ipsilateral R2 was more difficult to elicit, its latency is 40.28±3.32msec, but contralateral R2 was not evoked at all. The R1 and ipsilateral R2 latencies of Group III were significantly greater than those of control. We conclude that brain lesion combined with hyperbilirubinemia affect significantly blink reflex, especially R1(p<0.05) and ipsilateral R2(p<0.01) latencies. Thus we carefully suggest that blink reflex can be used as one of the screening tools for neonates with suspected brain lesion or hyperbilirubinemia.

Key Words: Blink reflex, Hyperbilirubinemia, Neurosonography, Neonate


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