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Journal of the Korean Academy of Rehabilitation Medicine 1991;15(4):405-411.
Electrodiagnostic study in cisplatin-induced peripheral neuropathy.
Kim, Jin Ho , Shin, Hee Suk , Chung, Sun Gun , Kim, Noe Kyeong , Heo, Dae Seog , Kang, Won Ki , Im, Young Hyuk
Department of Rehabilitation Medicine, Seoul National University college of Medicine * Department of Internal Medicine, Seoul National University College of Medicine
Cisplatin 독성에 의한 말초신경증의 전기진단학적 검사소견에 대한연구
김진호, 신희석, 정선근 * 김노경, 허대석, 강원기, 임영혁
서울대학교 의과대학 재활의학교실 * 서울대학교 의과대학 내과학교실

Cisplatin induced peripheral neuropathy is recently recognized as dose-limiting side effect of cisplatin anticancer therapy.

We did physical examination and electrodiagnostic studies of 21 patients with cisplatin chemotherapy to find out the factors related with cisplatin neuropathy and to make a criterias of patients who need electrodiagnostic studies to detect cisplatin neuropathy.

We concluded as follow:

1) Cisplatin neuropathy is mainly sensory axonopathy.

2) Cumulative dosage of cisplatin is the most important factor related with cisplatin neuropathy

3) The patients recieving more than 300㎎/㎡ of cisplatin in cumulative dosage should be done electrodiagnostic studies.

Key Words: Cisplatin, Neurotoxicity, Electrodiagnosis


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