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Journal of the Korean Academy of Rehabilitation Medicine 1992;16(4):378-384.
Immobilization hypokinesia and effect of electrical muscle stimulation on rat gastrocnemius muscle.
Kang, Yoon Kyoo , Kim, Chang Hwan , Suh, Dong Won
Department of Rehabilitation Medicine, Korea University, College of Medicine
체간 현수에 의한 백서 비복근의 근위축과 전기근육자극이 근위축에 미치는 영향
강윤규, 김창환, 서동원
고려대학교 의과대학 재활의학교실
Abstract

The suspension harness hindlimb hypokinesia are induced in rats by the modified Musacchia method. The animal was able to use its forelimbs to maneuver to obtain food and water. The hindlimbs were nonloaded bearing for 7 days. Electrical muscle stimulation(EMS) was performed to determine the efficacy of EMS as a means of preventing the muscle atrophy. The total body weight and wet gastrocnemius muscle weight are measured.

During the period of hypokinesia gastrocnemius wet muscle weight decreased but statistically not significant and there was evidence of muscle atrophy in tissue preparation. There was no difference between EMS group and non-EMS group.

It was concluded that no significant weight loss but muscle atrophy occured in suspended rat gastrocnemius muscle, and EMS method used in this study did not prevent the muscle atropy.

Key Words: Immobilization, Muscle atrophy, Electrical muscle stimulation


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