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Journal of the Korean Academy of Rehabilitation Medicine 1998;22(5):1056-1059.
How to Deal with the Latency of Unobtainable Responses in the Statistical Analysis.
Pyun, Seong Bom , Kwon, Hee Kyu , Lee, Hang Jae
Department of Rehabilitation Medicine, Korea University College of Medicine.
신경전도검사의 자료분석에서 유발되지 않은 전위의 잠시의 처리
편성범, 권희규, 이항재
고려대학교 의과대학 재활의학교실
Abstract

Objective
To evaluate the usability of near-nerve needle recording techniques in cases of unrecordable sensory nerve action potentials (SNAPs) with a surface electrode and to determine a proper alternative value of the missing latencies.


Method
Twenty six hands of 23 patients with a carpal tunnel syndrome (CTS) and an unobtainable median SNAP by surface electrode were evaluated by the near-nerve needle recording of median SNAPs. Using the nerve conduction data of 113 patients with CTS, we have established 3 alternative values: maximal, 95 percentile and predictive latencies. The alternative values were compared with the mean onset latencies by the near-nerve needle recordings of median SNAPs.


Results
Median SNAPs were obtainable in the 22 out of 26 hands by the near-nerve recording technique. The mean onset latency was 5.51⁑0.36 ms. The alternative values from 113 patients with CTS were as follows: maximum latency, 6.9 ms; 95 percentile latency, 5.6 ms; and predictive latency, 5.52 ms (Y = ⁣0.123* X ⁢ 5.52491; Y, onset latency; X, amplitude; r2=0.564; p=0.00). The Predictive latency was nearest to the mean onset latency.


Conclusion
To minimize the selection bias and statistical errors, the near nerve recording techniques proved to be a valuable method in cases of unrecordable SNAPs with surface electrode. For compensation of missing data, a proper alternative value can be obtained by the predictive latency calculated from a linear regression.

Key Words: Carpal tunnel syndrome, Sensory nerve action potential, Near-nerve needle recording techniques
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