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Journal of the Korean Academy of Rehabilitation Medicine 1999;23(5):961-967.
Relationship between Nocturnal Polyuria and Antidiuretic Hormone in Chronic Spinal Cord Injury.
Yu, Ji Yeon , Shin, Kyeong Ho , Kim, Jeong Tae , Bae, Ji Hyae , Park, Yeong Ok , Cho, Young Jin
1Department of Rehabilitation Medicine, Korea Veterans Hospital.
2Department of Rehabilitation Medicine, Samyook Rehabilitation Hospital.
만성 척수손상인에서 야간다뇨증과 항이뇨호르몬과의 상관관계
유지연, 신경호, 김정태, 배지혜, 박영옥, 조영진1
한국보훈병원 재활의학과, 1삼육재활병원 재활의학과
Abstract

Objective
To delineate the role of antidiuretic hormone (ADH) in relation to nocturnal polyuria, and to identify the factors influencing on the diurnal antidiuretic hormone level.


Method
The ADH was measured by radioimmuoassay at daytime (2:00 PM) and at nighttime (2:00 AM) with nocturnal polyuria group (11) and without nocturnal polyuria group (8). Urine volume, serum osmolarity, urine osmolarity, and blood pressure were also measured at the same time.


Results
1) The ADH at 2:00 AM did not increase in nocturnal polyuria group, although it increased in no-symptom group. 2) There was a statistically significant correlation between wheelchair ambulation time and daytime ADH level. 3) The difference of ADH level between daytime and nighttime showed decrease in orthostatic hypotension group.


Conclusion
There was relationship between nocturnal polyuria and diurnal variation of ADH level. The ADH concentration seems to be influenced by the postural factors and sympathetic factors.

Key Words: Antidiuretic hormone, Nocturnal polyuria, Serum osmolarity, Urine osmolarity, Orthostatic hypotension


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