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Journal of the Korean Academy of Rehabilitation Medicine 2000;24(2):230-236.
Electrodiagnostic Alteration to Temperature Effect in Demyelinating Peripheral Neuropathy.
Kim, Myeong Ok , Hwang, Sung Il , Jung, Han Young
Department of Rehabilitation Medicine, Inha University College of Medicine.
탈수초성 말초신경병증에서 체온 변화에 따른 전기진단학적 변화
김명옥, 황성일, 정한영
인하대학교 의과대학 재활의학교실

The purpose of this study was to determine the difference of temperature effects on the nerve conduction variables and to obtain correction factors for temperature in demyelinated and normal peripheral nerves.

The compound muscle action potentials (CMAPs) were recorded with wrist stimulation during cooling and warming in 10 control subjects and 13 subjects with demyelinating neuropathies. The temperature of cooling and warming were 18oC and 40oC, respectively. The time of cooling and warming were 60 minutes and composed of successive 4 sessions of 15 minutes. The skin temperature of thenar area, latency, amplitude, duration, and area of CMAPs were measured before and after each session of 15 minutes of cooling or warming.

The time constants of parameters of CMAPs were of higher tendency in cooling than in warming. The time constants of latency of CMAP were higher in subjects with demyelinating neuropathy than in controls (p<0.05): 33.3⁑4.0 minutes versus 27.2⁑2.2 minutes in cooling; 30.0⁑7.8 minutes versus 19.6⁑3.3 minutes in warming. The temperature correction factor of latency of CMAPs was ⁣0.23⁑0.03 msec/oC in control and ⁣0.33⁑0.06 msec/oC in subjects with demyelinating neuropathies (p<0.05).

When studying a subject with demyelinating neuropathies, we should warm the extremity for more sufficient time than in normal subject, or may applicate a differenct temperature correction factors.

Key Words: Time constant, Demyelinating peripheral neuropathy, Skin temperature, Time constant, Correction factor


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