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Journal of the Korean Academy of Rehabilitation Medicine 2000;24(3):432-438.
Prevalence of Cerebral Palsy in Very Low Birth Weight Infants.
Choi, Kyoung Hyo , Chun, Chang Sik , Kim, Hyung Joon , Sung, In Young , Ha, Sang Bae , Kim, Ki Soo , Pi, Soo Young
1Department of Rehabilitation Medicine, Asan Medical Center, University of Ulsan College of Medicine.
2Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine.
초저체중 출생아에서의 뇌성마비 유병률
최경효, 전창식, 김형준, 성인영, 하상배, 김기수1, 피수영1
울산대학교 의과대학 서울중앙병원 재활의학과, 1소아과
Abstract

Objective
To investigate the survival rate and the prevalence of cerebral palsy in very low birth weight (VLBW) and extremely low birth weight (ELBW) infants as well as the risk factors for the development of cerebral palsy.


Method
We reviewed medical records of 471 VLBW infants admitted to Asan medical center from 1989 to 1997 retrospectively.


Results
Ninety seven infants died before discharge from hospital, 7 died during follow-up, 55 status unknown due to discharge against medical advice, 26 discontinued follow-up. At corrected chronologic age of 2 years old, the prevalence of cerebral palsy was 10.5%, delayed development 4.5% and normal development 85.0%. Survival rate and prevalence of cerebral palsy among survivors remained statistically insignificant with time. Cerebral palsy was found in 8.5% of VLBW and 19.2% of ELBW. Decreasing gestation, abnormal neurosonographic findings, assisted ventilation, bronchopulmonary dysplasia, sepsis were risk factors associated with increased odds for cerebral palsy.


Conclusion
The prevalence of cerebral palsy in VLBW infants admitted to this hospital were comparable with recent studies from developed countries, and some of the predictors of cerebral palsy, ie, gestation period, neurosonographic findings, history of respirator use and sepsis, were also similar to those of western countries.

Key Words: Low birth weight infant, Cerebral palsy, Prevalence, Risk factor


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