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Journal of the Korean Academy of Rehabilitation Medicine 2000;24(6):1079-1085.
Visual Evoked Potential in Preterm Infants.
Lim, Seong Il , Lim, Jin Young , Kil, Eun Young , Seo, Hyae Jung , Oh, Yeon Kyun
1Department of Rehabilitation Medicine, Wonkwang University School of Medicine.
2Department of Pediatrics, Wonkwang University School of Medicine.
미숙아의 시각유발전위 검사
임성일, 임진영, 길은영, 서혜정, 오연균1
원광대학교 의과대학 재활의학교실 및 1소아과학교실
Abstract

Objective
The maturation in the central nervous system and the myelination of visual pathway were shown to be reflected by the visual evoked potential (VEP) response recordings. The purpose of this study was to establish normal value of flash visual evoked potentials in preterm infants, especially left to right difference.


Method
Forty-one preterm infants from 31 to 40 weeks of corrected age had been made VEP records using Cadwell Excel EMG/EP system. Some in whom weekly VEP records had been made at least 3 times were included in longitudinal study and others in occasionally VEP records were included in cross-sectional study. Infants with neurological problems or anomalies, perinatal infectious and other severe systemic disease were excluded.


Results
1) In the VEP study, we were able to establish the reference ranges for N300 peak latency at various corrected ages. 2) The latency of N300 peak latency was not significantly correlated with birth weight, sex, head circumference. 3) The latency of N300 peak decrease linearly, the age increased and also the decrement of N300 peak latency was accelerated at 37 weeks of gestational ages.


Conclusion
Although VEPs from preterm infants have several peaks, N300 latency is the most prominent and the most reproducible. It has been considered the most important component of the preterm VEPs.

Key Words: Visual evoked potential, Preterm infants


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