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Journal of the Korean Academy of Rehabilitation Medicine 2001;25(5):842-848.
Bone Metabolism in the Hemiplegic Patients after Stroke.
Kim, Young Eun , Jung, Tae Du , Lee, Ki Hoon , Park, Hyun , Lee, Yang Soo
1Department of Rehabilitation Medicine, College of Medicine, Kyungpook National University.
2Department of Rehabilitation Medicine, Daegu Veteran's Hospital.
뇌졸중으로 인한 편마비 환자의 골대사
김영은, 정태두, 이기훈, 박 현1, 이양수
경북대학교 의과대학 재활의학교실, 1대구보훈병원 재활의학과

To assess change of bone metabolism in hemiplegic patients after stroke.

Sera were collected from 19 hemiplegic patients after stroke. Sera were assayed for 25-hydroxyvitamin D (25-OHD), 1,25-dihydroxyvitamin D (1,25-(OH)2D), parathyroid hormone (PTH), calcium and osteocalcin.

Serum 25-OHD and 1,25-(OH)2D concentration were 15.13 mg/mL and 20.88 pg/mL, respectively. Serum PTH was 47.23 pg/mL. In 5 (26%) of the patients, the serum 25-OHD concentration were <10 ng/mL (deficient level). Ten (52%) of the patients had vitamin D concentrations between 10 and 20 ng/mL (insufficient level). The mean PTH concentration was not significantly higher in patients with deficient levels of 25-OHD (61.80 pg/mL) than those with insufficient (43.63 pg/mL) or sufficient (38.05 pg/mL) levels of 25-OHD. Serum 25-OHD concentration were lower in the late group (11.11 mg/mL) than in the early group (18.05 mg/mL), whereas serum PTH concentration were higher in the late group (58.96 pg/mL) than in the early group (38.70 pg/mL).

Compensatory hyperparathyroidism with hypovitaminosis D occurred in the hemiplgic patients after stroke, especially more than one year from onset.

Key Words: 25-hydroxyvitamin D (25-OHD), Parathyroid hormone (PTH), Hemiplegia, Stroke, Bone metabolism


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