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Journal of the Korean Academy of Rehabilitation Medicine 2003;27(3):335-339.
Effects of Hyperbaric Air Therapy on Cerebral Perfusion in Children with Cerebral Palsy.
Jung, Han Young , Han, Yoon Kyo , Hyun, In Young
1Department of Rehabilitation Medicine, Inha University Medical School, Korea. rmjung@inha.ac.kr
2Department of Nuclear Medicine, Inha University Medical School, Korea.
뇌성마비 아동에서 고압 공기가 뇌혈류 변화에 미치는 영향
정한영, 한윤교, 현인영1
인하대학교 의과대학 재활의학과, 1핵의학과
To evaluate the effects of hyperbaric air therapy (HAT) on cerebral perfusion for children with cerebral palsy.

The protocol for HAT consisted of consecutive 10 days in which a child and his/her caregiver were held in 1.3 atm hyperbaric air chamber for 60 minutes per one day. Nine children with cerebral palsy underwent 99mTc-HMPAO single-photon emission computed tomography (SPECT) before and after HAT. The change of regional cerebral blood flow (rCBF) was evaluated by subtraction analysis using statistical parametric mapping.

Average gestational age and birth weights were 34.0⁑5.1 months, and 2.3⁑1.2 kg, respectively. Two spastic quadriplegics, four spastic diplegics, two spastic hemiplegics, and one ataxic child were enrolled. In 3 out of 9 children, rCBF change was demonstrated; increased perfusion in right cerebellar hemisphere in child with diffuse brain atrophy and increased perfusion in diffuse cerebral cortex in child with left frontal leukoencephalopathy and decreased perfusion of right frontal cortex in child with right frontal leukoencephalopathy.

These findings suggest that HAT may recruit less excitable neurons that was of functionally silent in motor cortex, previously. However, increased rCBF following HAT protocol could not be ruled out whether the result of learning effects or HAT. (J Korean Acad Rehab Med 2003; 27: 335-339)

Key Words: Hyperbaric air therapy (HAT), Cerebral palsy, 99mTc-HMPAO SPECT, Brain plasticity


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