| The Correlation of Motor Impairment and Fractional Anisotropy in Diffusion Tensor Imaging in Post-stroke Hemiplegic Patients. |
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Park, Gi young , Ro, Hye jung , Lee, So young , Lim, Jung Geun , Paik, Seung kook , Chang, Yong min , Lee, Jun |
1Department of Rehabilitation Medicine, Dongsan Medical Center, Keimyung University College of Medicine, Korea. rohj93@hanmail.net
2Department of Neurology, Dongsan Medical Center, Keimyung University College of Medicine, Korea.
3Department of Diagnostic Radiology, Dongsan Medical Center, Keimyung University College of Medicine, Korea.
4Department of Diagnostic Radiology, Kungpook National University College of Medicine, Korea. |
| 뇌졸중 후 편마비 환자에서 확산 텐서 영상과 운동기능 손상과의 연관성 |
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박기영, 노혜정, 이소영, 임정근1, 백승국2, 장용민3, 이준1 |
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계명대학교 의과대학 재활의학교실, 1신경과학교실, 2진단방사선과학교실, 3경북대학교 의과대학 진단방사선과학교실 |
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| Abstract |
Objective
Diffusion tensor imaging (DTI) fully characterizes water molecule mobility, allowing an exploration of fiber tract integrity and orientation in the human brain. The purpose of this study was to investigate the correlation between motor impairment and the changes of fractional anisotropy (FA) in the internal capsule in post-stroke hemiplegic patients.
Method
Six normal subjects and 19 post-stroke hemiplegic patients who had a lesion in the internal capsule were included in this study. DTI was performed with a 3.0 Tesla MR at the mean interval of 28.2 days after stroke. Motor impairment was assessed with the Motricity Index and TrunkControl Test at the time of the imaging study. FA was measured in anterior limb and posterior limb of internal capsule.
Results
FA reduced significantly in the affected region compared with the other unaffected region in patients and normal region in controls. FA in the affected posterior limb of the internal capsule was correlated with the Motricity Index score of the affected upper limb (r=0.642, p＜0.05).
Conclusion
DTI can be helpful to evaluate motor impairment of the upper limb in post-stroke hemiplegic patients. (J Korean Acad Rehab Med 2004; 28: 122-125) |
| Key Words:
Diffusion tensor imaging, Stroke, Motor impairment |
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