| The Effect of the Suspension, Electrical Stimulation and Treadmill Training in the Hindlimb Muscle of the Rats. |
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Park, Jeong Mee , Kim, Sung Hoon , Jung, Soon Hee , Lee, Yang Tark , Kim, Ic Soo , Jang, Sang Min |
1Department of Rehabilitation Medicine, Yonsei University Wonju College of Medicine, Korea. kimrehab@hanmail.net
2Department of Pathology, Yonsei University Wonju College of Medicine, Korea. |
| 흰쥐에 대한 현수, 트레드밀 훈련과 전기자극이 종아리근에 미치는 효과 |
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박정미, 김성훈, 정순희1, 이양탁, 김익수, 장상민 |
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연세대학교 원주의과대학 재활의학교실, 1병리학교실 |
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| Abstract |
Objective
The purposes of this study were to investigate the effect of suspension, the electrical stimulation and full weight bearing treadmill training on the muscle atrophy and transformation of muscle fibers.
Method
Forty Spraque-Dawley rats were divided into control and 3 intervention groups: suspension control (n= 10), suspension with weight bearing treadmill (n=10), and suspension with electrical stimulation (n=10). After 4 weeks intervention, both gastrocnemius and soleus were dissected and the muscle weight and transformation of muscle fibers were analyzed.
Results
In suspension control and suspension electrical stimulation groups, muscle to body weight ratio of gastro-cnemius was decreased compared to control group (p＜0.05). In all intervention groups, muscle to body weight ratio of soleus was decreased compared to control group (p＜0.05). In suspension electrical stimulation group, type I muscle fiber ratio of gastrocnemius was increased compared to control and suspension control groups (p＜0.05). In suspension electrical stimulation group, type IIa muscle fiber ratio of gastrocnemius was increased compared to suspension control group (p＜0.05).
Conclusion
It is suggested that muscle atrophy induced by disuse and transformation of muscle fiber can be prevented by electrical stimulation intervention. (J Korean Acad Rehab Med 2004; 28: 358-365) |
| Key Words:
Muscle atrophy, Suspension, Electrical stimulation, Treadmill training |
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