Visual Evoked Potential Study in Amblyopia and Normal Groups.

, Kim, Kweon Young; , Shin, Su Beom; , Song, Ji Won

Original Article

Journal of the Korean Academy of Rehabilitation Medicine 2005;29(1):58-62.

Kim, Kweon Young , Shin, Su Beom , Song, Ji Won

Department of Rehabilitation Medicine, College of Medicine, Chosun University, Korea. shiri120@hanmail.net

약시 환자와 정상 대조군에서 시각유발전위검사의 소견

김권영, 신수범, 송지원

조선대학교 의과대학 재활의학교실

Abstract

Objective
The purpose of this study was to evaluate the relationship between the visual acuity and visual evoked potentials of the amblyopia patients and normal persons for the demonstration of the visual disability.
Method
We performed visual evoked potential study, in 49 eyes of the 43 amblyopia patients and in 76 eyes of 38 normal young adults. Our study was carried out to evaluate the relationship of the visual acuity with N₁, P₁, N₂, P₂ latency, P₁-N₂ amplitude and to compare the latency of N₁, P₁, N₂, P₂, and P₁-N₂ amplitude in amblyopia patients and normal young adults.
Results
The mean values of N₁, P₁, N₂, P₂ latency wereprolonged in amblyopia patients compared to normal young adults (p＜0.05). There was no correlation between the visual acuity and P₁ latency (p＞0.05), but significant correlation was noted between the visual acuity and P₁-N₂ amplitude (p＜0.05).
Conclusion
These results showed prolonged latency of N₁, P₁, N₂, P₂in amblyopia group as well as significant correlation between visual acuity and P₁-N₂ amplitude in both groups. So, P₁ latency and P₁-N₂ amplitude are good parameters in evaluating the visual disability. (J Korean Acad Rehab Med 2005; 29: 58-62)

Key Words: Amblyopia, Visual evoked potential, P₁ latency, Amplitude