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Journal of the Korean Academy of Rehabilitation Medicine 2005;29(4):371-376.
Serum Cystatin C for the Evaluation of Renal Function in the Spinal Cord Injured Patients.
Shin, Ji Cheol , Park, Chang Il , Song, Wonwoo , Kim, Eun Joo , Kim, Sang Hyun , Lee, Jin Woo
Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine. wonusong@yahoo.co.kr
척수손상 환자에서 혈청 Cystatin C를 이용한 신기능 평가
신지철, 박창일, 송원우, 김은주, 김상현, 이진우
연세대학교 의과대학 재활의학교실 및 재활의학연구소
To evaluate the renal function by investigating the relationship among serum cystatin C, serum creatinine, creatinine clearance and the average of bilateral ERPF (effective renal plasma flow) ratio of the MAG3 renal scan for the spinal cord injured patients.
Seventy-one spinal cord injured patients who admitted to our department were evaluated from January 2004 to October 2004. Blood samples and 24-hour urine of all the subjects were collected for measuring serum cystatin C, serum creatinine and creatinine clearance. MAG3 renal scan was done for 47 subjects. Regression analysis and Pearson's correlation methods were utilized for statistical analysis.
There was significant correlation between 1/cystatin C and creatinine clearance (p<0.001) and the correlation coefficient between 1/cystatin C vs. creatinine clearance (R= 0.552) was bigger than that between 1/creatinine and creatinine clearance (R=0.329). The reciprocal of cystatin C was positively correlated with the average of bilateral ERPF ratio of MAG3 renal scan (p=0.01), while there was no significant correlation between 1/creatinine and the average of bilateral ERPF ratio.
Measurement of serum cystatin C is a useful and convenient method for the evaluation of renal function in spinal cord injured patients. (J Korean Acad Rehab Med 2005; 29: 371-376)
Key Words: Cystatin C, Creatinine clearance, Renal function, Spinal cord injury


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