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Journal of the Korean Academy of Rehabilitation Medicine 2006;30(5):462-467.
The Effects of Single Event Multi-level Chemoneurolysis on Upper Extremity Function in Children with Cerebral Palsy.
Kim, Seong Woo , Park, Eun Sook , Shin, Ji Cheol , Shin, Jung Bin , You, Sung , Lee, Jee Sun
1Department of Rehabilitation Medicine, National Health Insurance Corporation Ilsan Hostpital, Korea. ksw228@nhimc.or.kr
2Yonsei University College of Medicine, Korea.
3Seoul Rehabilitation Hospital, Korea.
뇌성마비 아동에서 일회성 다부위 신경융해술이 상지 기능에 미치는 효과
김성우, 박은숙1, 신지철1, 신정빈, 유성, 이지선2
국민건강보험공단 일산병원 재활의학과, 1연세대학교 의과대학 재활의학교실, 2서울재활병원 재활의학과
To investigate the effects of single event multi- level chemoneurolysis (SEMLC) on the upper extremity function along with the improvement of spasticity in children with cerebral palsy.
SEMLC using botulinum toxin and 5% phenol solution was done for the upper extremities of 22 children with spastic cerebral palsy. In control group, 17 children with spastic cerebral palsy were enrolled. The assessment of spasticity (modified Ashworth scale) and upper extremity function (quality of upper extremity skills test, QUEST) before and 4 weeks after treatment were examined.
The spasticity of upper extremity was significantly reduced in SEMLC group compared with control group (p<0.05). The improvement of upper extremity function was significantly greater in SEMLC group than in control group (p<0.05). Children with spastic triplegia showed the largest change of QUEST compared with other types, but it wasn't statistically significant. In SEMLC group, initial QUEST score and the degree of improvement of QUEST after treatment showed significant negative correlation (p<0.05).
This study revealed SEMLC of the upper extremity in cerebral palsy was the effective treatment which could improve the upper extremity function as well as reduce the spasticity itself. (J Korean Acad Rehab Med 2006; 30: 462-467)
Key Words: Cerebral palsy, Spasticity treatment, Botulinum toxin, Phenol, Function of upper extremity


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