J Korean Acad Rehabil Med Search


Journal of the Korean Academy of Rehabilitation Medicine 2007;31(3):356-360.
Nocturnal Polyuria Developed in Patients with Central Pontine Myelinolysis: A case report.
Lee, Kwang Lae , Yim, Yoon Myung , Lim, Oh Kyung , Lee, Ju Kang , Bae, Keun Hwan , Kim, Sung Hwan , Choi, Chung Hwan , Jeong, Jeom Sun
Department of Rehabilitation, Gachon University of Medicine and Science, Korea. pm@gilhospital.com
뇌교 중심부 수초용해증 환자에서 발생한 야간 다뇨증 -증례 보고-
이광래, 임윤명, 임오경, 이주강, 배근환, 김성환, 최충환, 정점순
가천의과학대학교 재활의학교실
Central pontine myelinolysis is a demyelinating disease of central pons. Nocturnal polyuria is defined as increased urination during nighttime with a nocturnal fraction exceeding from 20% to 33%. We have experienced nocturnal polyuria developed in two patients with central pontine myelinolysis. In these cases, serum antidiuretic hormone and urine osmolality were lower at nighttime than daytime. It suggests that nocturnal polyuria is caused by abnormal diurnal variation of antidiuretic hormone. In the first case, nocturnal polyuria was recovered spontaneously and also follow up brain MRI showed decreased signal intensity in pons. In the second case, nocturnal polyuria was improved after the treatment of intranasal desmopressin. It appeares that central pontine myelinolysis can cause nocturnal polyuria due to the interruption of antidiuretic hormone pathway. The symptom of nocturnal polyuria can be treated by desmopressin. (J Korean Acad Rehab Med 2007; 31: 356-360)
Key Words: Central pontine myelinolysis, Nocturnal polyuria, Antidiuretic hormone


Browse all articles >

Terms of Use   |   Privacy Polity
Editorial Office
Department of Rehabilitation Medicine, Seoul National University Hospital
101 Daehak-ro, Jongno-gu, Seoul, Korea
Tel: +82-10-8678-2671    Fax: +82-2-6072-5244    E-mail: edit@e-arm.org; edit.karm@gmail.com
Business Registration: 110-82-07460                

Copyright © 2024 by Korean Academy of Rehabilitation Medicine.

Developed in M2PI

Close layer