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Journal of the Korean Academy of Rehabilitation Medicine 2008;32(1):116-118.
A Case of Fluoxetine Induced Mania in Poststroke Depression Patient: A case report.
Cho, Ye Rim , Kim, Hye Won , Lee, Jong In , Yun, Jong Soo , Lee, Jung Soo , Woo, Young Seop
1Department of Rehabilitation Medicine, The Catholic University of Korea College of Medicine, Korea. drlee71@catholic.ac.kr
2Department of Pychiatry, The Catholic University of Korea College of Medicine, Korea.
뇌졸중 후 우울증 환자에서 플루옥세틴에 의해 유발된 조증 1례 - 증례 보고 -
조예림, 김혜원, 이종인, 윤종수, 이정수, 우영섭1
가톨릭대학교 의과대학 재활의학교실, 1정신과학교실
Poststroke depression is very common and has been reported in as many as 40∼50% of poststroke patients. The fluoxetine is one of the most frequently prescribed drugs for the treatment of poststroke depression. This serotonin selective reuptake inhibitor, known as generally safe and well tolerated drug, has been recently reported to induce mania. We report a case of fluoxetine-induced mania. A 64 year-old male, who has taken 10 mg of fluoxetine daily due to poststroke depression, presented elevated mood, hyperactivity, regressed behavior, excessive planning, sleep deterioration, and talkativeness abruptly. We were suspicious of fluoxetine- induced manic state and discontinued immediately fluoxetine without prescription of mood stabilizer. His symptoms had been ceased over two weeks. (J Korean Acad Rehab Med 2008; 32: 116-118)
Key Words: Fluoxetine, Mania, Poststroke depression


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