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Journal of the Korean Academy of Rehabilitation Medicine 2009;33(6):742-745.
Wernicke's Encephalopathy Caused by Dysphagia in Down Syndrome: A case report.
Moon, Jeong Lim , Song, Dae Heon , Kwon, Jinook , Chung, You Chul
Department of Rehabilitation Medicine, College of Medicine, The Catholic University of Korea, Korea. lulruru@naver.com
다운 증후군에서 삼킴 장애와 연관된 베르니케뇌병증-증례 보고-
문정림, 송대헌, 권진욱, 정유철
가톨릭대학교 의과대학 재활의학교실
A subset of aged individuals with Down syndrome (DS) exhibits eating, drinking, and swallowing (EDS) difficulties, which have the potential to lead to life-threatening conditions such as malnutrition. We report a case of 37-year-old woman with DS, who developed Wernicke's encephalopathy related to malnutrition that was caused by EDS problems. The patient presented with a history of EDS problems for 2 years without treatment and had developed mental-status changes, unsteadiness of stance and gait with associated MRI findings, corresponding to Wernicke's encephalopathy. The patient was treated with nutritional support including thiamine replacement and dysphagia rehabilitation therapy. Our case highlights the importance of early and proper management of malnutrition associated with EDS problems in adult DS. The suspicion of Wernicke's encephalopathy must be considered when adult DS manifests as prolonged malnutrition, altered mentality and decreased mobility. (J Korean Acad Rehab Med 2009; 33: 742-745)
Key Words: Down syndrome, Wernicke's encephalopathy, Dysphagia


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