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"Sodium hyaluronate"

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"Sodium hyaluronate"

Original Articles
Subacromial Bursa Injection of Hyaluronate with Steroid in Patients with Peri-articular Shoulder Disorders
Seung Deuk Byun, Dong Hwi Park, Won Duck Choi, Zee Ihn Lee
Ann Rehabil Med 2011;35(5):664-672.   Published online October 31, 2011
DOI: https://doi.org/10.5535/arm.2011.35.5.664
Objective

To investigate the additive effect of sono-guided subacromial bursa injection of hyaluronate with steroid in patients with peri-articular shoulder disorders.

Method

This prospective randomized controlled trial involved 26 patients who had shoulder pain. Group A, consisting of 13 patients, was treated with a sono-guided subacromial bursa injection containing a mixture of 0.5% lidocaine (5 ml) and triamcinolone 40 mg (1 ml), followed by injection with sodium hyaluronate (2 ml) once a week for 3 weeks. The other 13 patients (Group B) were treated with a sono-guided subacromial bursa injection containing a mixture of 0.5% lidocaine (5 ml) and triamcinolone 40 mg (1 ml) once a week for 3 weeks. The effects were assessed using a visual analogue scale (VAS) of shoulder pain, active range of motion (AROM), shoulder function assessment scale (SFA), shoulder disability questionnaire (SDQ) at study entry and every week from first injection until 4 weeks after the 1st injection (= 2 weeks after 3rd injection).

Results

(1) Demographic features and all parameters measured before injection did not show a significant difference between the 2 groups. (2) Statistically significant improvements were shown in VAS, SFA, SDQ during the 1st, 2nd, and 4th week after the first injection in both groups (p<0.05). (3) SFA showed significant improvement at 1 week after injection only in group A (p<0.05). (4) AROM of internal rotation showed significant improvement at week 4 after the 1st injection only in group A (p<0.05).

Conclusion

Subacromial bursa injection of hyaluronate with steroid in patients with peri-articular shoulder disorders has additive effects on functional improvement of the affected shoulder, including the AROM of internal rotation.

Citations

Citations to this article as recorded by  
  • Comparison of three common shoulder injections for rotator cuff tears: a systematic review and network meta-analysis
    Xinzhao Jiang, Hong Zhang, Qing Wu, Yun Chen, Tian Jiang
    Journal of Orthopaedic Surgery and Research.2023;[Epub]     CrossRef
  • Efficacy of hyaluronic acid in rotator cuff pathology compared to other available treatment modalities: A Systematic Review and meta-analysis
    Shivam Bansal, Balgovind S. Raja, Bishwa Bandhu Niraula, Anil Regmi, Arghya Kundu Choudhury, Divyansh Sharma, Mohit Dhingra
    Journal of Orthopaedic Reports.2023; 2(3): 100157.     CrossRef
  • Comparison of single platelet-rich plasma injection with hyaluronic acid injection for partial-thickness rotator cuff tears
    Shou-Hsien Huang, Po-Cheng Hsu, Kevin A. Wang, Chen-Liang Chou, Jia-Chi Wang
    Journal of the Chinese Medical Association.2022; 85(6): 723.     CrossRef
  • Cross-Linked Hyaluronate and Corticosteroid Combination Ameliorate the Rat Experimental Tendinopathy through Anti-Senescent and -Apoptotic Effects
    Po-Yen Ko, Che-Chia Hsu, Shih-Yao Chen, Li-Chieh Kuo, Wei-Ren Su, I-Ming Jou, Fong-Chin Su, Po-Ting Wu
    International Journal of Molecular Sciences.2022; 23(17): 9760.     CrossRef
  • Transcranial direct current stimulation (a-tCDS) after subacromial injections in patients with subacromial pain syndrome: a randomized controlled pilot study
    Samuel Larrivée, Frédéric Balg, Guillaume Léonard, Sonia Bédard, Michel Tousignant, Patrick Boissy
    BMC Musculoskeletal Disorders.2021;[Epub]     CrossRef
  • Acromioclavicular osteoarthritis and shoulder pain: a review of the role of ultrasonography
    Matteo Precerutti, Manuela Formica, Mara Bonardi, Caterina Peroni, Francesco Calciati
    Journal of Ultrasound.2020; 23(3): 317.     CrossRef
  • The effectiveness of 2 consecutive intra-articular polydeoxyribonucleotide injections compared with intra-articular triamcinolone for hemiplegic shoulder pain
    Donghwi Park, Kwang Jae Yu, Ju Young Cho, Seung Beom Woo, Junu Park, Zeeihn Lee, Jong Min Kim
    Medicine.2017; 96(46): e8741.     CrossRef
  • Le rilonacept dans le traitement de la bursite sous-acromiale : étude ouverte randomisée de non-infériorité contre l’acétonide de triamcinolone
    Matthew B. Carroll, Spencer A. Motley, Susanna Wohlford, Bryan C. Ramsey
    Revue du Rhumatisme.2016; 83(5): 377.     CrossRef
  • Rilonacept in the treatment of subacromial bursitis: A randomized, non-inferiority, unblinded study versus triamcinolone acetonide
    Matthew B. Carroll, Spencer A. Motley, Susanna Wohlford, Bryan C. Ramsey
    Joint Bone Spine.2015; 82(6): 446.     CrossRef
  • Suprascapular Nerve Block versus Intra-articular Hyaluronic Acid Injection in Hemiplegic Shoulder Pain
    Sang-Hyun Kim, Dong Suk Kim
    Brain & Neurorehabilitation.2014; 7(2): 118.     CrossRef
  • Effects of Subacromial Bursa Injection With Corticosteroid and Hyaluronidase According to Dosage
    Won Duck Choi, Dong Hyun Cho, Yong Ho Hong, Jae Hyun Noh, Zee Ihn Lee, Seung Deuk Byun
    Annals of Rehabilitation Medicine.2013; 37(5): 668.     CrossRef
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Treatment of Adhesive Capsulitis with Steroid Injection Followed by Hyaluronic Acid Injection.
Kim, Chul , Park, Yongbum , Youn, Jo Eun , Kim, Duk You
J Korean Acad Rehabil Med 2010;34(3):310-315.
Objective
To investigate the effects of sono-guided intraarticular steroid injection followed by sodium hyaluronate injection weekly for 2 weeks on adhesive capsulitis of the shoulder Method: In this prospective randomized controlled trial, 16 patients (group A) were treated with intraarticular injection with a mixture of 0.5% lidocaine 9 ml and triamcinolone 40 mg once a week for 3 weeks, and 13 patients (group B) were treated with intraarticular injection with a mixture of 0.5% lidocaine 9 ml and triamcinolone 40 mg for the first week, and subsequently a mixture of 0.5% lidocaine 8 ml and sodium hyaluronate 2 ml once a week for the next 3 weeks. A self exercise program was instructed for all subjects. The effects were assessed using visual numeric scale (VNS), shoulder pain and disability index (SPADI), and range of shoulder motion (flexion, abduction, internal rotation. external rotation, and extension) at study entry, every week until 2 weeks have passed after the last injection. Results: The VNS, SPADI, and range of shoulder motion improved 1 week after 1st injection and continued to improve until 2 weeks after last injection in both two groups. There were no difference in changes of VNS and SPADI between these two groups, but range of shoulder motion especially in passive and active internal rotation of patients in group A improved more than those in group B. Conclusion: Steroid injection combined with hyaluronic acid injection has comparable effects with triamcinolone for treatment of adhesive capsulitis of the shoulder. Sono-guided intraarticular injection of steroid combined with hyaluronic acid can substitute for intraarticular injection of triamcinolone and be useful especially for patients susceptible to adverse effects of steroid injection. (J Korean Acad Rehab Med 2010; 34: 310-315)
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Evaluation of the Efficacy of Sodium Hyaluronate to Degerative Osteoarthritis of the Knee.
Ko, Jae Young , Yun, Suk Bong , So, En Ha , Cho, En Su
J Korean Acad Rehabil Med 1999;23(4):842-847.

Objective: To obtain a effect of intraarticular injection of Sodium Hyaluronate in the patient with degenerative osteoarthritis without restriction of activities of daily living.

Method: Twenty-five patients were participated in this study. These patients are diagnosed as degenerative osteoarthritis by clinical symtoms and radiographic findings. Sodium hyaluronate, 2.5 ml, 3 mg/ampule, were injected intraarticulary without local anesthesia once a week for 5 times consecutively. For evaluation of the effectiveness of sodium hyaluronate, we assess the parameters for subjective and objective symtoms scored from 0 to 3 on 3 items, and for activities of daily living scored from 0 to 4 on 4 items. And then, we compared these data between pre-injection and at post-injection 2, 4, and 5 weeks. Changes of subjective and objective symtoms, and activities of daily living are assessed using Kellgren's X-ray grading of degenerative osteoarthritis. Improvement of the subjective pain is recorded by visual analogue scale.

Results: 1. Subjective and objective symtoms, and activities of daily living with time progression were significantly increased at post-injection 4, 5 weeks compared with pre-injection status (P<0.05). 2. Subjective and objective symtoms, and activities of daily living according to Kellgren's X-ray classification were significantly increased at stage II and III (P<0.05). 3. Visual analogue scale is significantly decreased after injection (P<0.05).

Conclusion: Intraarticular injection of sodium hyaluronate showed improvement of patient's subjective and objective symtoms, and activities of daily living. The improvement was pronounced in the cases of high grade of degenerative osteoarthritis (stage II, III) according to Kellgren's X-ray classification as well as low grade (Stage I).

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