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Original Articles

Cardiopulmonary rehabilitation

Development and Validation of a Clinically Actionable Prediction Model for Postoperative Pulmonary Complications in Cardiac Surgery: A Focus on Modifiable Risk Factors
Ruoxi Li, Meice Tian, Chuangshi Wang, Yujia Huang, Weinan Chen, Ya Song, Bomiao Liu, Liu Du, Xue Feng
Ann Rehabil Med 2026;50(1):50-61.   Published online February 26, 2026
DOI: https://doi.org/10.5535/arm.250092
Objective
To develop and validate a clinically actionable prediction model for postoperative pulmonary complications (PPCs) in cardiac surgery patients, focusing on modifiable preoperative risk factors amenable to targeted optimization.
Methods
In this prospective observational cohort study, 492 adults undergoing open-chest cardiac surgery between August 15, 2023 and December 31, 2023 were analyzed. Prespecified predictors included gas exchange variables, pulmonary function, inspiratory muscle strength, and physical performance. Univariable and multivariable logistic regression analyses were used to develop the prediction model. Discrimination was assessed by the area under the receiver operating characteristic curve (AUC).
Results
A total of 90 patients (14.1%) developed PPCs after surgery. Five independent predictors were identified: elevated arterial PaCO2 (odds ratio [OR] 1.12, 95% confidence interval [CI] 1.00–1.26), oxygen desaturation (SpO2<93%) (OR 12.47, 95% CI 3.51–48.13), reduced gait speed (OR 0.17, 95% CI 0.04–0.71), lower FEV1/FVC ratio (OR 0.96, 95% CI 0.92–1.00), and diminished inspiratory muscle strength (MIP % predicted) (OR 0.96, 95% CI 0.92–0.99). The model demonstrated good discriminative ability with an AUC of 0.86 (95% CI 0.80–0.93) in the training cohort and 0.87 (95% CI 0.74–0.93) in the validation cohort.
Conclusion
This parsimonious model achieved high predictive accuracy using five modifiable physiological variables. By targeting abnormalities in gas exchange, pulmonary mechanics, muscle strength, and functional reserve, the model offers a practical tool to guide individualized prehabilitation strategies for reducing PPC risk in cardiac surgery patients.

Citations

Citations to this article as recorded by  
  • Preoperative Albumin Infusion Reduced Pulmonary Complications in Elderly Patients With Hypoalbuminemia Undergoing Cardiac Surgery: A Single‐Center, Randomized, Double‐Blind, Controlled Pilot Trial
    Jie Liu, Shiqiang Chen, Yunxiao Bai, Yong Lv, Yanting Wang, Zhenzhen Xu, Nianguo Dong, Qingping Wu
    MedComm.2026;[Epub]     CrossRef
  • 1,751 View
  • 25 Download
  • 1 Web of Science
  • 1 Crossref

Pain & Musculoskeletal rehabilitation

Assessment of Back Muscle Activity Using High-Density Surface Electromyography in Patients With Degenerative Thoracolumbar Kyphosis: A Preliminary Study
Yuki Kurokawa, Yuichi Nishikawa, Noriaki Yokogawa, Takaki Shimizu, Satoru Demura, Satoshi Kato
Ann Rehabil Med 2026;50(1):22-32.   Published online February 23, 2026
DOI: https://doi.org/10.5535/arm.250126
Objective
To examine back muscle activity and fatigue behavior in female patients with degenerative thoracolumbar kyphosis (DTK) using high-density surface electromyography (HDSEMG) and evaluate the effects of using a soft spinal orthosis.
Methods
Seven female participants with DTK (mean age: 73.6 years) were assessed during static standing and a weighted holding task with and without a soft spinal orthosis. HDSEMG signals were obtained from the lumbar erector spinae using a 64-electrode array. Time to fatigue (TTF), spatial displacement, and directional consistency of muscle activation were analyzed using the spatial center of activity (SCoA) and circular variance (CV).
Results
Orthosis use significantly reduced the sagittal vertical axis and low back pain. TTF was significantly prolonged during the weighted holding task with the orthosis (p=0.012), indicating delayed fatigue onset. SCoA displacement was significantly reduced in both tasks (p<0.001), whereas CV analysis demonstrated improved directional consistency of muscle activation.
Conclusion
HD-SEMG revealed early fatigue onset and unstable muscle activation patterns in patients with DTK, particularly during load-bearing tasks performed without orthotic support. Orthosis used improved endurance and neuromuscular efficiency by reducing spatial and directional variability in muscle recruitment. These findings underscore the utility of HDSEMG for elucidating the neuromuscular pathophysiology of DTK and support the use of spinal orthoses as a conservative treatment approach.
  • 2,034 View
  • 60 Download

Physical therapy

Cold Compression and Ischemic Preconditioning With Ice Therapy Enhance Muscle Recovery and Functionality Post-Exercise: A Randomized Study
Robert Trybulski, Adrian Kużdżał, Andryi Vovkanych, Yaroslav Svyshch, Gracjan Olaniszyn, Jakub Taradaj
Ann Rehabil Med 2025;49(6):411-425.   Published online December 31, 2025
DOI: https://doi.org/10.5535/arm.250090
Objective
To compare the immediate recovery effects of cold compression (CC) and ischemic preconditioning with ice (IPCice) on muscle recovery, this study was conducted.
Methods
Athletes were randomly assigned to CC (n=12), IPCice (n=12), or control (n=12) groups. All participants completed a fatigue-inducing jump rope protocol targeting the gastrocnemius prior to recovery interventions. CC involved 20 minutes of alternating pressure (25–75 mmHg) on the gastrocnemius muscles. IPCice involved thigh cuffs inflated to 200 mmHg (2 minutes on/off cycles for 20 minutes) with manual ice application. Thirty-six amateur mixed martial arts (MMA) athletes. Muscle pain, congestion, strength, creatine kinase, muscle stiffness, perfusion, pressure pain threshold, reactive strength index, and total quality recovery were assessed at rest, post-exercise, post-treatment, and 48 hours later.
Results
Post-treatment, CC significantly improved perfusion (p<0.001) and reduced muscle soreness in both legs compared to IPCice and control (p≤0.02). CC also resulted in significantly higher PPT values (p≤0.006). Benefits on some variables remained at 48 hours.
Conclusion
Both modalities enhanced recovery following fatiguing exercise; however, CC demonstrated superior effectiveness in attenuating fatigue-related impairments, particularly in perfusion, soreness, and muscle function, highlighting its practical advantage over IPCice for MMA athletes.
  • 1,969 View
  • 76 Download

Review Article

Pediatric rehabilitation

Assessment and Management of Adolescent Idiopathic Scoliosis: From the Perspective of a Physiatrist
Yang-Chin Su, Chi-Kuang Feng, Tsui-Fen Yang
Ann Rehabil Med 2025;49(5):263-278.   Published online October 31, 2025
DOI: https://doi.org/10.5535/arm.250097
Adolescent idiopathic scoliosis (AIS) is the most encountered spinal deformity in growing children, which may bring significant impacts on patients’ physical function, appearance, and overall quality of life. A physiatrist plays a crucial role in the early diagnosis of AIS and longitudinal management through continuous care. Contemporary management for AIS is according to the skeletal maturity, the magnitude of the spinal curves, and the risk of progression. For mild curves, therapeutic exercises, particularly physiotherapeutic scoliosis-specific exercises (PSSE), are employed as a conservative approach to improve postural symmetry and reduce the risk of curve progression. Bracing is required for moderate curves from 25 to 45 degrees in skeletally immature cases. Strict compliance with bracing is critical for therapeutic success. In cases that are rapidly progressive or in severe curves exceeding 40 to 45 degrees, spinal fusion surgery is considered the definitive treatment. Recent advancements in non-fusion and motion-preserving techniques provide alternative options to traditional fusion surgery. To protect maximal neurological function, intraoperative neurophysiological monitoring (IONM) is currently the trend for spinal deformity correction surgery. The care for AIS patients is an individualized, multidisciplinary, patient-centered, growth-sensitive approach, aiming to optimize outcomes and minimize long-term complications. This review outlines a comprehensive rehabilitation-oriented strategy for AIS patients from the perspective of a physiatrist, encompassing clinical assessment, conservative management with observation, therapeutic exercises, bracing, and further considerations in referral to spinal surgery.

Citations

Citations to this article as recorded by  
  • Evaluating the Effectiveness of sEMG Biofeedback for Posture Training and Scoliosis Management
    Yiu-Hong Wong, Mei-chun Cheung, Qi-Wen Emma Lei, Joanne Yip, Yoel A. Klug
    BioMed Research International.2026;[Epub]     CrossRef
  • Interrelationships among 3D spinal alignment variables during active self-correction in adolescents with idiopathic scoliosis
    Arkadiusz Żurawski, Sun-Young Ha
    European Spine Journal.2026;[Epub]     CrossRef
  • Three-Dimensional Surface Topography for the Assessment of Spinal Alignment: A Cross-Sectional Study of Biomechanical Correlates
    Brigitte Osser, Csongor Toth, Gyongyi Osser, Laura Ioana Bondar, Liliana-Oana Pobirci, Florin Mihai Marcu, Ramona Nicoleta Suciu, Nicoleta Anamaria Pascalau, Adina Mincic, Corina Dalia Toderescu
    Diagnostics.2026; 16(10): 1445.     CrossRef
  • Economic evaluation of school scoliosis screening in Gannan Tibetan autonomous prefecture, Gansu Province: a cost-utility analysis based on decision tree-Markov model
    Shaobo Yang, Juan Wang, Peiji Miao, Chen Zhang, Jin Huang, Xiaoyun Yuan, Yanxiang Zhang, Xiaohui Dou, Zhenheng Zhang, Zhe Liu, Jianjun Duan, Xueting Xu, Jiantao Wen, Shunjun Cui, Xiaole Zhu
    Frontiers in Public Health.2026;[Epub]     CrossRef
  • Comment on “Automatic radiation-free evaluation of Cobb angle for spinal curvature based on fringe projection profilometry and deep learning technology”
    Y. M. Manu, Suresha Devaraju, B. M. Praveen
    Spine Deformity.2026;[Epub]     CrossRef
  • Factors Associated With Follow-Up Attendance After School Scoliosis Screening: A Pilot Cross-Sectional Study
    Takuya Nagai, Syuji Kurogi, Kiyoshi Higa, Shota Amano, Takayuki Matsumoto, Takumi Takahashi, Naosuke Kamei
    Cureus.2026;[Epub]     CrossRef
  • 8,168 View
  • 136 Download
  • 6 Web of Science
  • 6 Crossref

Original Articles

Dysphagia

Temporal and Kinematic Measurements of Hyoid Bone Excursion in Patients With Head and Neck Cancer
Sheng-Hao Cheng, Kuo-Chang Wei, Tyng-Guey Wang, Ming-Yen Hsiao
Ann Rehabil Med 2025;49(4):234-245.   Published online August 29, 2025
DOI: https://doi.org/10.5535/arm.250005
Objective
To investigate the temporal and kinematic parameters of hyoid bone excursion (HBE) in head and neck cancer (HNC) patients with and without aspiration.
Methods
Videofluoroscopic swallowing study images from 28 HNC patients were divided into aspiration and non-aspiration groups. The kinematic parameters of HBE, including displacement, instantaneous velocity, and instantaneous acceleration, as well as the timing of reaching maximal values in these parameters, were analyzed.
Results
The timings of reaching maximal horizontal (2.37±1.10 seconds vs. 1.09±1.58 seconds, p=0.010; 0.68±0.28 vs. 0.37±0.26, p=0.010 for percentage of time), vertical (1.83±2.06 seconds vs. 0.86±1.42 seconds, p=0.020) and hypotenuse instantaneous velocities (2.36±1.96 seconds vs. 0.79±1.20 seconds, p=0.006; 0.60±0.33 vs. 0.33±0.24, p=0.028 for percentage of time), as well as the timings of reaching maximal horizontal (2.22±1.50 seconds vs. 0.90±1.26 seconds, p=0.009; 0.60±0.32 vs. 0.37±0.29, p=0.041 for percentage of time), vertical (2.09±1.94 seconds vs. 0.83±1.19 seconds, p=0.003), and hypotenuse instantaneous accelerations (2.49±1.93 seconds vs. 0.81±1.24 seconds, p=0.004; 0.65±0.34 vs. 0.34±0.28, p=0.026 for percentage of time) were significantly prolonged in the aspiration group. After signal smoothing, the aspiration group exhibited delayed timing in reaching maximal horizontal instantaneous velocity (2.07±1.09 seconds vs. 0.74±1.10 seconds, p=0.004; 0.58±0.29 vs. 0.32±0.24, p=0.017 for percentage of time), as well as maximal horizontal (2.18±1.16 seconds vs. 1.12±1.46 seconds, p=0.008) and hypotenuse accelerations (2.21±2.50 seconds vs. 0.81±1.21 seconds, p=0.011). There were no significant between-group differences in other kinematic parameters, except for horizontal displacement (7.66±6.26 mm vs. 12.14±5.82 mm, p=0.042).
Conclusion
The timings of reaching maximal instantaneous velocities and accelerations of HBE, rather than the maximum values of these kinematic parameters, may be critical parameters related to aspiration in HNC patients.
  • 2,467 View
  • 48 Download

Physical therapy

Unilateral Vibratory Stimulation Inhibits Contralateral Spinal Anterior Horn Cells in Homonymous Muscles for the First 75 Seconds
Kenta Kunoh, Takahiro Takenaka, Daisuke Kimura, Toshiaki Suzuki
Ann Rehabil Med 2025;49(4):226-233.   Published online August 22, 2025
DOI: https://doi.org/10.5535/arm.240107
Objective
To investigate muscle tone changes over time in contralateral homonymous muscles when unilateral muscles are stimulated, using F-wave measurements, we examined whether vibratory stimulation on the contralateral homonymous muscle of the affected side may reduce spasticity, whose optimal duration remains unclear.
Methods
Vibratory stimulation was applied to the right hand of healthy adults, using parameters of 80 Hz frequency, 0.4 mm amplitude, 400 g load, and 195 seconds of duration on the abductor digiti minimi muscle. F-wave was measured in the left hand before stimulation, at seven intervals during stimulation, and immediately after.
Results
The F/M amplitude ratio decreased immediately at stimulation onset, at 30 seconds, and at 60 seconds compared to baseline. A least-squares analysis revealed a negative slope from baseline to 60 seconds (f(x)=-0.11x+1.12), while the slope became positive after 90 seconds, continuing after stimulation ended (f(x)=0.04x+0.82).
Conclusion
Unilateral vibratory stimulation may decrease excitability in the spinal anterior horn cells of the contralateral homonymous muscle for up to 75 seconds post-stimulation, suggesting a potential mechanism for spasticity management.
  • 3,395 View
  • 61 Download

Review Article

Spinal cord injury

The Effects of Inspiratory Muscle Training in Individuals With Cervical Spinal Cord Injuries: A Systematic Review and Meta-Analysis
Dat Huu Tran, Ha Thi Le, Tho Thi Quynh Chu, Hung Thi Cam Pham, Anh Ngoc Van Le
Ann Rehabil Med 2025;49(3):152-163.   Published online June 17, 2025
DOI: https://doi.org/10.5535/arm.250013
Correction in: Ann Rehabil Med 2025;49(4):257
The effect of inspiratory muscle training (IMT) on cervical spinal cord injury (SCI) remains controversial. This study aimed to assess the efficacy of IMT in enhancing breathing muscle strength, pulmonary function, and quality of life (QoL) among patients with cervical SCI. A search was performed using the PubMed, Cochrane Library, Scopus, Embase, and Web of Science databases through December 2023. This review was conducted according to PRISMA guidelines and the Cochrane Library Handbook. The meta-analysis used mean differences (MDs) or standardized mean differences to pool the results. The Risk of Bias 2 and the GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) were used to assess the methodological quality of the included studies. This systematic review included five randomized controlled trials (202 participants). The results of the meta-analysis showed that IMT significantly improved maximal inspiratory pressure (MIP) with MD 12.13 cmH2O (95% confidence interval [CI] 4.22 to 20.03), maximal expiratory pressure (MEP) with MD 8.98 cmH2O (95% CI 6.96 to 11.00), and vital capacity (VC) with MD 0.25 L (95% CI 0.21 to 0.28). There were no significant improvements in forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), and QoL. The quality of the evidence ranged from very low to moderate, owing to bias and heterogeneity. Our results showed that IMT may improve MIP, MEP, and VC, but not FEV1, FVC, or QoL, in patients with cervical SCI. Further large-scale studies are required to determine this effect’s optimal dosage and duration.

Citations

Citations to this article as recorded by  
  • Rewiring the Lung–CNS Axis After Spinal Cord Injury
    HaiRong Wu, Xiaolong Li, Wenjun Zhao, Yihan Li, Hang Zhang, Heng Yin, Xiaofeng Gu
    Journal of Inflammation Research.2026; Volume 19: 1.     CrossRef
  • Effects of whole-body vibration training on sarcopenia in older adults: a systematic review and meta-analysis of randomized controlled trials
    Jaewon Beom, Jae-Young Lim, Sang Yoon Lee
    Scientific Reports.2026;[Epub]     CrossRef
  • RESPIRATORY MUSCLE TRAINING IN SPORTS AND REHABILITATION: A LITERATURE REVIEW
    Martyna Łubianka, Wiktor Słyś
    International Journal of Innovative Technologies in Social Science.2026;[Epub]     CrossRef
  • Effects of Electrostimulation With the Laparoscopic Implantation of Neuroprosthesis Procedure Combined With Cardiorespiratory Physiotherapy on the Functional Rehabilitation of Individuals With Chronic Spinal Cord Injury: Quasirandomized Prospective Contro
    Wellington Contiero, Augusta Ribeiro Morgado, Victor Croos-Bezerra, Cristiano Soares Simões, João Angelo Ferres Brogin, Jean Faber, Nucelio Lemos
    Neuromodulation: Technology at the Neural Interface.2026;[Epub]     CrossRef
  • Determinants for improving respiratory muscle training after spinal cord injury using real-world clinical data
    Gabi Mueller, Marianne Tanner, Amelie Gruber, Sabrina Alessandri, Claudio Perret, Andreas Limacher
    Spinal Cord.2026;[Epub]     CrossRef
  • 13,232 View
  • 198 Download
  • 3 Web of Science
  • 5 Crossref

Original Articles

Pain & Musculoskeletal rehabilitation

Effect of Soft Surface Stepping Exercise on Physical Activity Among Community-Dwelling Elderly: A Prospective Randomized Controlled Trial
Chonticha Kaewjoho, Puttipong Poncumhak, Pacharee Manoy, Suphannika Ladawan, Narongsak Khamnon
Ann Rehabil Med 2025;49(2):91-103.   Published online April 22, 2025
DOI: https://doi.org/10.5535/arm.240119
Objective
To investigate the effects of modified stepping exercises over six weeks on functional mobility and individual lower extremity muscle strength in community-dwelling older individuals.
Methods
This prospective randomized controlled trial design was conducted in thirty-two older adults who completed a modified stepping exercises program (n=16 for soft-surface stepping exercise; n=16 for firm-surface stepping exercise). These exercises were practiced for 50 minutes/day, three days/week, over six weeks. They were assessed for their functional mobility relating to levels of independence at baseline, after 4 weeks, after 6 weeks of intervention, and at 1 month after the last intervention sessions.
Results
Both groups showed significant improvements in functional mobility, lower extremity muscle strength, and walking speed after 4 and 6 weeks of intervention, as well as at the one-month follow-up. However, the soft-surface stepping exercise group exhibited significantly greater improvements in dynamic balance (p=0.035) and lower extremity muscle strength (p=0.015) compared to the firm-surface stepping exercise group after 6 weeks of intervention. Additionally, the soft-surface group demonstrated superior gains in hip flexor (p=0.041), hip extensor (p=0.047), hip adductor (p=0.026), and hip abductor strength (p=0.046), with these enhancements maintained at the one-month follow-up.
Conclusion
Soft-surface stepping exercise that involves whole-body movements offers a promising alternative to promote independence and safety among community-dwelling older adults. This study underscores the need for future research to evaluate the sustained impact of these benefits post-intervention, particularly during a retention period following the intervention.
  • 6,156 View
  • 137 Download

Cardiopulmonary rehabilitation

Would Integrating Inspiratory Muscle Training into Pulmonary Rehabilitation of Adults with Burn Injuries Have Any Advantageous Effects? a Randomized, Double-Blind, Sham-controlled Study
Nabil Mahmoud Abdel-Aal, Maged A. Basha, Saleh M. Aloraini, Alshimaa R. Azab, FatmaAlzahraa H. Kamel
Ann Rehabil Med 2025;49(1):30-39.   Published online February 28, 2025
DOI: https://doi.org/10.5535/arm.240092
Objective
To determine the effectiveness of adding inspiratory muscle training (IMT) alongside a pulmonary rehabilitation protocol in terms of inspiratory muscle strength, lung function, and exercise capacity in burned adults.
Methods
A randomized, double-blinded, sham-controlled study. Fifty-two adult patients with burn injuries, more than 20 years old and at least 20% total body surface area, were assigned randomly either to the experimental or the conventional group. The participants in the experimental group were given IMT plus a pulmonary rehabilitation program; the conventional group received only a pulmonary rehabilitation program. The interventions were performed for 8 weeks. At the beginning and after 8 weeks of training, the respiratory muscles’ strength, lung function and exercise capacity were all examined.
Results
After 2 months of training, the experimental group demonstrated statistically significant improvements than conventional group in maximum inspiratory pressure, maximum expiratory pressure, 6-minute walk test, forced vital capacity, and forced expiratory volume in 1 second (p<0.05).
Conclusion
An 8-week IMT program coupled with pulmonary rehabilitation increases respiratory muscle strength, pulmonary functions, and functional capacity in burn patients. IMT is a beneficial and efficient therapy that can be easily implemented for burn patients.

Citations

Citations to this article as recorded by  
  • The Effect of Inspiratory Muscle Training on Fatigue Among Burn Patients in Iraq
    Zahraa Fayyadh Abd Hussein Al-Amiri, Alaa Jawad Kadhim, Hadi Ahmadi Chenari, Steven L. Baumann
    Nursing Science Quarterly.2026;[Epub]     CrossRef
  • 5,782 View
  • 95 Download
  • 1 Web of Science
  • 1 Crossref

Brain disorders

Feasibility of Computerized Visuomotor Integration System for Visual Field Defects and Spatial Neglect in Poststroke Patients
Hyeon-Taek Hong, Myeong Geun Jeong, Kyoung Tae Kim
Ann Rehabil Med 2024;48(2):146-154.   Published online April 25, 2024
DOI: https://doi.org/10.5535/arm.230028
Objective
To develop a computerized visuomotor integration system for assessment and training of visual perception impairments and evaluate its safety and feasibility in patients with a stroke. Visual field defects and spatial neglect lead to substantial poststroke impairment. Most diagnostic assessments are anchored in traditional methods, and clinical effects of rehabilitation treatments are limited.
Methods
The CoTras Vision system included two evaluations and four training modules. The evaluation modules were based on the Albert’s test and Star cancellation test, and training modules were based on visual tracking, central-peripheral integration, and visuomotor perception techniques. Bland–Altman plots for agreement with the traditional paper-and-pencil test were performed, and the modified Intrinsic Motivation Inventory, Patient Satisfaction Questionnaire, and Simulator Sickness Questionnaire were conducted.
Results
Ten patients with acute stroke completed the study. Bland–Altman plots revealed good agreements for Albert’s test (mean difference, -0.3±4.5) and Star cancellation test (mean difference, 0.3±0.7). The mean±standard deviation scores of the modified Intrinsic Motivation Inventory, Patient Satisfaction Survey, and Simulator Sickness Questionnaire were 84.7±30.6, 40.5±7.9, and 34.0±34.5 respectively.
Conclusion
The CoTras Vision system is feasible and safe in patients with stroke. Most patients had a high degree of motivation to use the system and did not experience severe adverse events. Further studies are needed to confirm its usefulness in stroke patients with visual field defects and hemineglect symptoms. Furthermore, a large, well-designed, randomized controlled trial will be needed to confirm the treatment effect of the CoTras Vision system.

Citations

Citations to this article as recorded by  
  • Tablet computer-based cognitive training for visuomotor integration in children with developmental delay: a pilot study
    Jee Hyun Suh, Soo Jeong Han, Sun Ah Choi, Hyesung Yang, Sihyun Park
    BMC Pediatrics.2024;[Epub]     CrossRef
  • 6,562 View
  • 90 Download
  • 1 Web of Science
  • 1 Crossref

Pain & Musculoskeletal rehabilitation

Preclinical Study of Dual-Wavelength Light-Emitting Diode Therapy in an Osteoarthritis Rat Model
Won Woo Choi, Sung Hoon Kim, Ji Hyun Kim, Kyungmin Kim, Sun Jung Kim, Minwoo Kim, Han-Sung Kim, Hana Lee, Ji Yong Lee, Sang Yeol Yong
Ann Rehabil Med 2023;47(6):483-492.   Published online December 6, 2023
DOI: https://doi.org/10.5535/arm.23138
Objective
To evaluate the efficacy of light-emitting diode (LED) and their dual-wavelengths as a treatment strategy for osteoarthritis.
Methods
We induced osteoarthritis in male Sprague-Dawley rats by intra-articular injection of sodium iodoacetate into the right rear knee joint. The animals with lesions were divided into an untreated group and an LED-treated group (n=7 each). In the LED-treated group, the lesioned knee was irradiated with lasers (850 and 940 nm) and dose (3.15 J/cm2) for 20 minutes per session, twice a week for 4 weeks. Knee joint tissues were stained and scanned using an in vivo micro-computed tomography (CT) scanner. Serum interleukin (IL)-6 and IL-18 levels were determined using enzyme-linked immuno-sorbent assay. Several functional tests (lines crossed, rotational movement, rearing, and latency to remain rotating rod) were performed 24 hours before LED treatment and at 7, 14, 21, and 28 days after treatment.
Results
LED-treated rats showed improved locomotor function and suppressed matrix-degrading cytokines. Micro-CT images indicated that LED therapy had a preserving effect on cartilage and cortical bone.
Conclusion
LED treatment using wavelengths of 850 and 940 nm resulted in significant functional, anatomical, and histologic improvements without adverse events in a rat model. Further research is required to determine the optimal wavelength, duration, and combination method, which will maximize treatment effectiveness.

Citations

Citations to this article as recorded by  
  • Effects of Dual Wavelength Photobiomodulation on Osseointegration in Grafted Areas
    Lucas de Sousa Goulart Pereira, Julia Raulino Lima, Elcio Marcantonio, Priscilla Barbosa Ferreira Soares, Suzane Cristina Pigossi, Guilherme José Pimentel Lopes de Oliveira
    Lasers in Surgery and Medicine.2026; 58(5): 429.     CrossRef
  • BTEX-K Ameliorates Rheumatoid Arthritis Through Regulating the NF-κB and PPAR-γ Signaling Pathways in Incomplete Freund’s Adjuvant-Induced Arthritis Mice
    Joonpyo Hong, Jin-Ho Lee, Ga Young Lee, Jin-Hwan Oh, Hana Lee, Han Sung Kim, Tack-Joong Kim
    Biomedicines.2025; 13(7): 1524.     CrossRef
  • Photobiomodulation Literature Watch December 2023
    James D. Carroll
    Photobiomodulation, Photomedicine, and Laser Surgery.2024; 42(10): 660.     CrossRef
  • 7,058 View
  • 97 Download
  • 2 Web of Science
  • 3 Crossref

Geriatric Rehabilitation

Association of Diaphragm Thickness and Respiratory Muscle Strength With Indices of Sarcopenia
Yookyung Lee, Sunhan Son, Don-Kyu Kim, Myung Woo Park
Ann Rehabil Med 2023;47(4):307-314.   Published online August 28, 2023
DOI: https://doi.org/10.5535/arm.23081
Objective
To evaluate the relationship between respiratory muscle strength, diaphragm thickness (DT), and indices of sarcopenia.
Methods
This study included 45 healthy elderly volunteers (21 male and 24 female) aged 65 years or older. Sarcopenia indices, including hand grip strength (HGS) and body mass index-adjusted appendicular skeletal muscle (ASM/BMI), were measured using a hand grip dynamometer and bioimpedance analysis, respectively. Calf circumference (CC) and gait speed were also measured. Maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) were obtained using a spirometer, as a measure of respiratory muscle strength. DT was evaluated through ultrasonography. The association between indices of sarcopenia, respiratory muscle strength, and DT was evaluated using Spearman’s rank correlation test, and univariate and multiple regression analysis.
Results
ASM/BMI (r=0.609, p<0.01), CC (r=0.499, p<0.01), HGS (r=0.759, p<0.01), and gait speed (r=0.319, p<0.05) were significantly correlated with DT. In the univariate linear regression analysis, MIP was significantly associated with age (p=0.003), DT (p<0.001), HGS (p=0.002), CC (p=0.013), and gait speed (p=0.026). MEP was significantly associated with sex (p=0.001), BMI (p=0.033), ASM/BMI (p=0.003), DT (p<0.001), HGS (p<0.001), CC (p=0.001) and gait speed (p=0.004). In the multiple linear regression analysis, age (p=0.001), DT (p<0.001), and ASM/BMI (p=0.008) showed significant association with MIP. DT (p<0.001) and gait speed (p=0.050) were associated with MEP.
Conclusion
Our findings suggest that respiratory muscle strength is associated with DT and indices of sarcopenia. Further prospective studies with larger sample sizes are needed to confirm these findings.

Citations

Citations to this article as recorded by  
  • Association between diaphragm thickness and postoperative complications in elderly patients with non-small-cell lung cancer
    Shoji Kuriyama, Motoko Konno, Naoko Mori, Sumire Shibano, Shinogu Takashima, Tsubasa Matsuo, Yusuke Sato, Kyoko Nomura, Yoshihiro Minamiya, Kazuhiro Imai
    Surgery Today.2026; 56(3): 293.     CrossRef
  • Lumbar paraspinal muscle quality and disability in older adults: insights from the SarcoSpine cohort
    Dong Hyun Kim, Yoon-Hee Choi, JooHee Lee, Sang Yoon Lee
    BMC Geriatrics.2026;[Epub]     CrossRef
  • Identifying dynapenia using ventilatory parameters in patients with heart failure with preserved ejection fraction: cross-sectional analysis of the FUNNEL+ study
    C. García-Conejo, C. Roldán-Jiménez, M.A. Pérez-Velasco, R. Gómez-Huelgas, L.M. Pérez-Belmonte, A.I. Cuesta-Vargas
    Revista Clínica Española (English Edition).2026; 226(4): 502494.     CrossRef
  • Identificación de la dinapenia mediante parámetros ventilatorios en pacientes con insuficiencia cardiaca con fracción de eyección preservada: análisis transversal del estudio FUNNEL+
    C. García-Conejo, C. Roldán-Jiménez, M.A. Pérez-Velasco, R. Gómez-Huelgas, L.M. Pérez-Belmonte, A.I. Cuesta-Vargas
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    International Journal of Chronic Obstructive Pulmonary Disease.2025; Volume 20: 1.     CrossRef
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    Takahiro Shinohara, Toru Yamada, Shuji Ouchi, Suguru Mabuchi, Ryoichi Hanazawa, Kazuharu Nakagawa, Kanako Yoshimi, Tatsuya Mayama, Ayane Horike, Kenji Toyoshima, Yoshiaki Tamura, Atsushi Araki, Haruka Tohara, Akihiro Hirakawa, Takuma Kimura, Takeshi Ishid
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    European Journal of Applied Physiology.2025; 125(12): 3769.     CrossRef
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  • Short-term resistance training enhances functional and physiological markers in older women: implications for biomechanical and health interventions in aging
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    Fernanda Bueno Pilastri, Nise Ribeiro Marques, Julia Fantim Lopez, Francieli da Silva, Marcelo Tavella Navega
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    Fernanda Bueno Pilastri, Nise Ribeiro Marques, Julia Fantim Lopez, Francieli da Silva, Marcelo Tavella Navega
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    Naiara Kássia Macêdo da Silva Bezerra, Elis Fernanda Araújo Lima de Oliveira, Bárbara Bernardo Figueirêdo, Paulo Adriano Schwingel, Paulo André Freire Magalhães
    Physiotherapy Research International.2025;[Epub]     CrossRef
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  • Effects of Tai Chi combined with Dynamic Neuromuscular Stabilization on postural control and balance in post-stroke patients with sarcopenia: protocol for a randomised single-blind controlled trial
    Jie Zhuang, Dorota Duhova, Lei Song, Tingting Meng, Mengxue Sun, Zekai Hu, Jue Wang, Junwen Long, Yimin Shen, Yueren Liu, Wenshu Guo, Jin Hu, Fen Rao, Tingting Shi, Xu-chen Tao, Lei Fang
    BMJ Open.2025; 15(10): e107506.     CrossRef
  • Waiting is the hardest part: patient, caregiver and clinician perspectives on shaping prehabilitation support strategies in liver transplantation
    Suzanne M Lester, Bronwen Connolly, Brenda O’Neill, Johnny Cash, Roger McCorry, Judy M Bradley
    Frontline Gastroenterology.2025; : flgastro-2025-103374.     CrossRef
  • Respiratory Sarcopenia: A Comprehensive Review
    Tae Sung Park, Hari Ryu, Myung-Jun Shin
    Annals of CardioPulmonary Rehabilitation.2025; 5(2): 23.     CrossRef
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    Shinjiro Miyazaki, Akira Tamaki, Hidetaka Wakabayashi, Hidenori Arai
    Current Opinion in Clinical Nutrition & Metabolic Care.2024; 27(3): 210.     CrossRef
  • Diaphragm Ultrasound in Different Clinical Scenarios: A Review with a Focus on Older Patients
    Carmine Siniscalchi, Antonio Nouvenne, Nicoletta Cerundolo, Tiziana Meschi, Andrea Ticinesi
    Geriatrics.2024; 9(3): 70.     CrossRef
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    Kazunori Okada, Akiko Kamiya, Yusuke Yanagi, Masahiro Nakabachi, Yasuhiro Hayashi, Michito Murayama, Sanae Kaga
    WFUMB Ultrasound Open.2024; 2(2): 100052.     CrossRef
  • Evaluation of the Functional Reserve and Exercise Tolerance in Patients with CHF in Clinical Trials (Consent Document of the Editorial board of the Journal of Cardiology, the Board of the Society of Specialists in Heart Failure (SSHF) and Working Group “N
    Yu. L. Begrambekova, G. P. Arutynov, M. G. Glezer, N. A. Karanadze, E. A. Kolesnikova, T. A. Lelyavina, A. S. Lishuta, Ya. A. Orlova, Yu. N. Belenkov
    Kardiologiia.2024; 64(7): 4.     CrossRef
  • Validating respiratory sarcopenia diagnostic criteria by mortality based on a position paper by four professional organizations: Insights from the Otassha study
    Takeshi Kera, Hisashi Kawai, Manami Ejiri, Keigo Imamura, Hirohiko Hirano, Yoshinori Fujiwara, Kazushige Ihara, Shuichi Obuchi
    Geriatrics & Gerontology International.2024; 24(9): 948.     CrossRef
  • Evaluating Respiratory Muscle Strength in Sarcopenia Screening among Older Men in South Korea: A Retrospective Analysis
    Tae Sung Park, Sa-Eun Park, Ki-Hun Kim, Sang Hun Kim, Myung Hun Jang, Myung-Jun Shin, Yun Kyung Jeon
    The World Journal of Men's Health.2024; 42(4): 890.     CrossRef
  • Tongue pressure, respiratory muscle and limb strength and functional exercise capacity in oesophageal cancer
    Takuya Fukushima, Makoto Yamasaki, Nobuyuki Yamamoto, Yasuaki Arima, Takashi Harino, Soshi Hori, Yuki Hashimoto, Masaya Kotsuka, Kentaro Inoue, Kimitaka Hase, Jiro Nakano
    BMJ Supportive & Palliative Care.2024; 14(4): 434.     CrossRef
  • 12,391 View
  • 240 Download
  • 24 Web of Science
  • 28 Crossref

Cardiopulmonary rehabilitation

Validation of Wearable Digital Devices for Heart Rate Measurement During Exercise Test in Patients With Coronary Artery Disease
Chul Kim, Jun Hyeong Song, Seung Hyoun Kim
Ann Rehabil Med 2023;47(4):261-271.   Published online August 4, 2023
DOI: https://doi.org/10.5535/arm.23019
Objective
To assess the accuracy of recently commercialized wearable devices in heart rate (HR) measurement during cardiopulmonary exercise test (CPX) under gradual increase in exercise intensity, while wearable devices with HR monitors are reported to be less accurate in different exercise intensities.
Methods
CPX was performed for patients with coronary artery disease (CAD). Twelve lead electrocardiograph (ECG) was the gold standard and Apple watch 7 (AW7), Galaxy watch 4 (GW4) and Bio Patch Mobicare 200 (MC200) were applied for comparison. Paired absolute difference (PAD), mean absolute percentage error (MAPE) and intraclass correlation coefficient (ICC) were evaluated for each device.
Results
Forty-four participants with CAD were included. All the devices showed MAPE under 2% and ICC above 0.9 in rest, exercise and recovery phases (MC200=0.999, GW4=0.997, AW7=0.998). When comparing exercise and recovery phase, PAD of MC200 and AW7 in recovery phase were significantly bigger than PAD of exercise phase (p<0.05). Although not significant, PAD of GW4 tended to be bigger in recovery phase, too. Also, when stratified by HR 20, ICC of all the devices were highest under HR of 100, and ICC decreased as HR increased. However, except for ICC of GW4 at HR above 160 (=0.867), all ICCs exceeded 0.9 indicating excellent accuracy.
Conclusion
The HR measurement of the devices validated in this study shows a high concordance with the ECG device, so CAD patients may benefit from the devices during high-intensity exercise under conditions where HR is measured reliably.

Citations

Citations to this article as recorded by  
  • The accuracy of Apple Watch measurements: a living systematic review and meta-analysis
    Rory Lambe, Maximus Baldwin, Ben O’Grady, Moritz Schumann, Brian Caulfield, Cailbhe Doherty
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    Marcello Sicbaldi, Laura Bartoli, Jose Albites-Sanabria, Ilaria D’Ascanio, Alessandro Silvani, Lorenzo Chiari, Alberto Camon, Luca Palmerini
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    Amin Roshdy Soliman, Gehad Maghraby, Farouk Mostafa Faris, Amany Abouzeid, Rabab Mahmoud Ahmed, Ebtesam Fahmy, Mona Hegazy, Alia A. Saleh, Shereen Abdelghaffar, Inass Shaltout
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    Allan Inoue, João Paulo Ferreira Soares, Felipe Antunes-Santos, Alexandre Ferreira, Alberto Gonçalves, João Arthur Alcântara, Marcelo Rodrigues dos Santos
    JMIR Cardio.2026; 10: e81917.     CrossRef
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    Mei Li, Jichao Xu
    Frontiers in Public Health.2026;[Epub]     CrossRef
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    Paulien Vermunicht, Katsiaryna Makayed, Christophe Buyck, Lieselotte Knaepen, Juan Sebastian Piedrahita Giraldo, Sebastiaan Naessens, Wendy Hens, Emeline Van Craenenbroeck, Kris Laukens, Lien Desteghe, Hein Heidbuchel
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    Tatiana Pereira Filgueiras, Pedro Bertemes-Filho, Fabrício Noveletto
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    Daisuke Higuchi, Yuko Takahashi, Shigeya Tanaka, Yosuke Tomita
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    Haniel Fernandes
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  • 20 Crossref

Dysphagia

Clinical and Swallowing Characteristics Related With Respiratory Infection in Parkinsonism Patients
Ji Su Jung, Heewon Jeon, Byung-Mo Oh, Han Gil Seo
Ann Rehabil Med 2023;47(2):138-146.   Published online April 30, 2023
DOI: https://doi.org/10.5535/arm.22152
Objective
To investigate the clinical and swallowing characteristics related to respiratory infection in patients with parkinsonism.
Methods
One hundred and forty-two patients with parkinsonism who underwent videofluoroscopic swallowing studies (VFSS) were enrolled in this study. The initial clinical and VFSS characteristics were compared between patients with and without a history of respiratory infection in the past year. A multivariate logistic regression model was applied to identify clinical and swallowing characteristics related to respiratory infections.
Results
Patients with respiratory infections were older (74.75±10.20 years vs. 70.70±8.83 years, p=0.037), had a higher Hoehn and Yahr (H&Y) stage (stage IV–V, 67.9% vs. 49.1%; p=0.047), and were more likely to have a diagnosis of idiopathic Parkinson’s disease (IPD) (67.9% vs. 41.2%, p=0.011) than those without respiratory infections. Among VFSS findings, bolus formation, premature bolus loss, oral transit time, pyriform sinus residues, pharyngeal wall coatings, and penetration/aspiration were significantly worse in patients with respiratory infections (p<0.05). Regarding clinical characteristics, higher H&Y stage (odds ratio [OR], 3.174; 95% confidence interval [CI], 1.226–8.216; p=0.017) and diagnosis of IPD (OR, 0.280, 95% CI, 0.111–0.706; p=0.007) were significantly related to respiratory infections in the multivariate analysis. Among VFSS findings, pyriform sinus residue (OR, 14.615; 95% CI, 2.257–94.623; p=0.005) and premature bolus loss (OR, 5.151; 95% CI, 1.047–25.338; p=0.044) were also significantly associated with respiratory infection.
Conclusion
This study suggests that disease severity, diagnosis, pyriform sinus residue, and premature bolus loss observed in VFSS are associated with respiratory infection in patients with parkinsonism.
  • 5,899 View
  • 123 Download

Cancer rehabilitation

Outcomes of a Multi-Modal Hospital-Associated Home-Based Cancer Prehabilitation Program
Kah Meng Kwok, San San Tay
Ann Rehabil Med 2023;47(1):52-67.   Published online January 30, 2023
DOI: https://doi.org/10.5535/arm.22126
Objective
To assess the impact of a “one-stop”, multi-modal, hospital-associated-home-based prehabilitation model, helmed by a small core team, on newly diagnosed gastrointestinal and urological cancer patients planned for surgery.
Methods
This is a retrospective study in a tertiary public hospital, involving all newly diagnosed gastrointestinal and urological cancer patients planned for surgery. The primary outcome measure was the 6-minute walk test (6MWT). Other outcomes included physical, psychological and quality-of-life measures, and patient satisfaction surveys, taken at baseline, pre-operatively (post-prehabilitation), and at 3 months post-operatively.
Results
When comparing the baseline to pre-operatively (post-prehabilitation), there was a statistically significant improvement in the 6MWT (21.52 m, p<0.001), 30-Second Sit to Stand test (STS) (1.08 repetitions, p<0.001), Timed Up and Go test (TUG) (0.83 seconds, p=0.014) and Hospital Anxiety and Depression Scale (HADS) (total score 1.77, p<0.001). These were sustained (6MWT: 0.22, p=0.964; STS: 0.08 repetitions, p=0.863; TUG: 0.04 seconds, p=0.939) or further improved (HADS total score 2.06, p=0.003) at 3 months post-operatively. There was also a statistically significant improvement in the EuroQol-5 dimension health score (health-related quality-of-life measure) from baseline to 3 months post-operatively (7.04 points, p=0.001), with more than 90% overall patient satisfaction reported.
Conclusion
Prehabilitation applied via our model resulted in significant improvements in functional capacity, psychological and quality-of-life outcomes, sustained at 3 months post-operatively, and is a feasible and effective approach that is well-received by our patients.

Citations

Citations to this article as recorded by  
  • Effects of a functional training prehabilitation program supported by the Prehab® App on functional capacity in preoperative oncological patients
    Monique Messaggi-Sartor, Raquel Sebio Garcia, Marta Amor-Barbosa, David Blanco, Graciela Martinez-Pallí
    Supportive Care in Cancer.2026;[Epub]     CrossRef
  • A prototype smartwatch for monitoring dynamic, compound and plyometric exercises in cancer prehabilitation: a development and validation study
    San San Tay, Hanushyah Devi, Shannon Yap, Abbas Bin Zainul Abideen, Xuan Han Koh, Daniel Leong
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    Emmanuel G. Villalpando, Jamie Fertal, Finly Zachariah, Jeannine M. Brant, Jessica T. Cheng
    Current Oncology.2026; 33(7): 387.     CrossRef
  • Feasibility, User Acceptance, and Outcomes of Using a Cancer Prehabilitation App for Exercise: Pilot Cohort Study
    Fuquan Zhang, Deepali Bang, Christine Alejandro Visperas, Mon Hnin Tun, San San Tay
    JMIR Formative Research.2025; 9: e64427.     CrossRef
  • Participation and Adherence to Prehabilitation Programs for Colorectal Cancer
    Misha Sier, Eva Godina, Omar Mollema, Maud Cox, Thais Tweed, Jan Greve, Jan Stoot
    Nutrients.2025; 17(11): 1792.     CrossRef
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    Katarzyna Nowicka-Sauer, Adam Zemła, Dorota Banaszkiewicz, Bartosz G. Trzeciak, Krzysztof Jarmoszewicz
    Anaesthesiology Intensive Therapy.2024; 56(1): 9.     CrossRef
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    André van Zundert, Stephen P. Gatt, Tom Christophe van Zundert
    Saudi Journal of Anaesthesia.2023; 17(4): 557.     CrossRef
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  • 129 Download
  • 8 Web of Science
  • 7 Crossref

Cardiopulmonary rehabilitation

Effect of the Inspiratory Method and Timing of Voluntary Cough on Peak Cough Flow
Fumiya Kotajima, Masakiyo Yatomi, Takeshi Hisada
Ann Rehabil Med 2023;47(2):118-128.   Published online January 30, 2023
DOI: https://doi.org/10.5535/arm.22103
Objective
To define the effect of the inspiratory method and cough timing on peak cough flow (PCF).
Methods
We investigated the effect of measurement conditions on PCF in healthy subjects (n=10). We then compared obstructive and restrictive pulmonary diseases (n=20) to assess for similar results in respiratory diseases. The PCF was measured under four conditions: before coughing, without maneuver 1 or with maneuver 2 a temporary respiratory pause (4–6 seconds) after rapid inspiration, and without maneuver 3 or with maneuver 4 a temporary respiratory pause after slow inspiration. After the measurements were completed, the PCF between the four conditions was compared for each subject group, and the effect size was calculated.
Results
PCF of maneuvers 1 and 3 were significantly higher than maneuver 4 in healthy subjects (476.34±102.05 L/min and 463.44±107.14 L/min vs. 429.54±116.83 L/min, p<0.01 and p<0.05, respectively) and patients with restrictive pulmonary disease (381.96±145.31 L/min, 354.60±157.36 L/min vs. 296.94±137.49 L/min, p<0.01 and p<0.05, respectively). In obstructive pulmonary disease, maneuver 1 was significantly higher than maneuver 4 (327.42±154.73 L/min vs. 279.48±141.10 L/min, p<0.05). The largest effect sizes were shown by maneuvers 4 and 1.
Conclusion
PCF depends on changes in inspiratory speed before coughing and on temporary respiratory pauses after maximal inspiration. It will become necessary to unify the measurement methods for coughing strength and present appropriate coughing methods.

Citations

Citations to this article as recorded by  
  • Objective Assessment of the Cough: Listening to the Patient’s Voice. A Narrative Review
    Tai Joon An
    Tuberculosis and Respiratory Diseases.2026; 89(2): 193.     CrossRef
  • Factors related to pre-operative cough strength in cardiac surgical patients: a cross-sectional study
    Yan Zhang, Zheng Lin, Yuhong Chen, Liang Hong, Xiao Shen
    Heart & Lung.2024; 63: 128.     CrossRef
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  • 121 Download
  • 2 Web of Science
  • 2 Crossref

Others

Exploratory Investigation of the Effects of Tactile Stimulation Using Air Pressure at the Auricular Vagus Nerve on Heart Rate Variability
Hyun Jeong Lee, Soohyun Wi, Sungwoo Park, Byung-Mo Oh, Han Gil Seo, Woo Hyung Lee
Ann Rehabil Med 2023;47(1):68-77.   Published online January 4, 2023
DOI: https://doi.org/10.5535/arm.22119
Objective
To explore the effects of tactile stimulation using air pressure at the auricular branch of the vagus nerve on autonomic activity in healthy individuals.
Methods
Three types of tactile stimulation were used in this study: continuous low-amplitude, continuous high-amplitude, and pulsed airflow. The tactile stimulations were provided to the cymba concha to investigate autonomic activity in 22 healthy participants. The mean heart rate (HR) and parameters of HR variability, including the standard deviation of R-R intervals (SDNN) and root mean square of successive R-R interval differences (RMSSD) were compared at baseline, stimulation, and recovery periods.
Results
Two-way repeated measures ANOVA indicated a significant main effect of time on HR (p=0.001), SDNN (p=0.003), and RMSSD (p<0.001). These parameters showed significant differences between baseline and stimulation periods and baseline and recovery periods in the post-hoc analyses. There were no significant differences in the changes induced by stimulation type and the interaction between time and stimulation type for all parameters. One-way repeated measures ANOVA showed that HR, SDNN, and RMSSD did not differ significantly among the three time periods during sham stimulation.
Conclusion
Parasympathetic activity can be enhanced by auricular tactile stimulation using air pressure, targeting the cymba concha. Further studies are warranted to investigate the optimal stimulation parameters for potential clinical significance.

Citations

Citations to this article as recorded by  
  • Bridging the gap from mechanism to clinic: a translational perspective on taVNS for gastrointestinal disorders
    Jian Cui, Jingxue Zhao, Shuanglin Zhou
    Frontiers in Neuroscience.2026;[Epub]     CrossRef
  • Effects of tactile auricular vagus nerve stimulation using heated and humidified airflow on cardiac autonomic activity: a pilot experimental study
    Soohyun Wi, Sungwoo Park, Byung-Mo Oh, Han Gil Seo, Yae Lim Lee, Woo Hyung Lee
    Clinical Autonomic Research.2025; 35(3): 519.     CrossRef
  • Auricular neuromodulation may act through interoception modulation
    Frédéric Canini, Damien Claverie, Florence Weill, Christine Pailler, Béatrice Paquier, Mireille Michel-Cherqui, Sonia Pellissier, Marion Trousselard, Emmanuel Sagui
    Brain Research.2025; 1863: 149736.     CrossRef
  • Stroking Stimuli to the Ear to Enhance Pleasant and Non-arousing Feelings while Listening to Sounds
    Yuta GOTO, Shogo OKAMOTO
    International Journal of Affective Engineering.2024; 23(3): 251.     CrossRef
  • Relaxation Effects of Auricular Vibration Stimuli Synchronized with Music
    Yuta GOTO, Shogo OKAMOTO
    International Symposium on Affective Science and Engineering.2024; ISASE2024: 1.     CrossRef
  • 13,152 View
  • 138 Download
  • 4 Web of Science
  • 5 Crossref

Electrodiagnosis

Hemodynamic Consideration in Intraoperative Neurophysiological Monitoring in Neuromuscular Scoliosis Surgery
Seok Young Chung, Chae Hwan Lim, Yoon Ghil Park, Hak Sun Kim, Dawoon Kim, Jinyoung Park
Ann Rehabil Med 2022;46(6):292-302.   Published online December 31, 2022
DOI: https://doi.org/10.5535/arm.22100
Objective
To prove the hypothesis that the parameters of intraoperative neurophysiological monitoring (IONM) during will be more deteriorated in neuromuscular scoliosis (NMS) than in adolescent idiopathic scoliosis (AIS).
Methods
This retrospective study reviewed the data of 69 patients (NMS=32, AIS=37) who underwent scoliosis surgery under IONM. The amplitude of motor evoked potentials (MEPs), and the amplitude and the latency of somatosensory evoked potentials (SEPs) were examined. Demographic, preoperative, perioperative and postoperative data were analyzed to determine whether they affected the IONM parameters for each group.
Results
Of the items analyzed, the bleeding amount was the only significant risk factor for SEP latency deterioration in the NMS group only. The amplitude of SEP and MEP did not correlate with the hemodynamic parameters. The NMS/AIS ratios of the bleeding-related parameters were higher in the order of bleeding amount/weight (2.62, p<0.01), bleeding amount/body mass index (2.13, p<0.01), and bleeding amount (1.56, p<0.01). This study suggests that SEP latency is more vulnerable than SEP or MEP amplitude in ischemic conditions during scoliosis surgery.
Conclusion
In NMS patients, it should be considered that the bleeding amount can have a critical effect on intraoperative electrophysiological deterioration.

Citations

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  • Cerebral Perfusion Unveiled: A Comprehensive Review of Blood Pressure Management in Neurosurgical and Endovascular Aneurysm Interventions
    Shubham Petkar, Vivek Chakole, Roshan Nisal, Vishnu Priya
    Cureus.2024;[Epub]     CrossRef
  • Improvement in functional motor scores in patients with non-ambulatory spinal muscle atrophy during Nusinersen treatment in South Korea: a single center study
    Jin A. Yoon, Yuju Jeong, Jiae Lee, Dong Jun Lee, Kyung Nam Lee, Yong Beom Shin
    BMC Neurology.2024;[Epub]     CrossRef
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  • 100 Download
  • 2 Web of Science
  • 2 Crossref

Physical Therapy

Effects of Intensive Exercise on Cognitive Dysfunction in Patients With Pure Cerebellar Degeneration: A Single-Arm Pilot Study
Toshiya Shimamoto, Katsuhisa Uchino, Akira Mori, Kengo Nojima, Junichi Iiyama, Yohei Misumi, Mitsuharu Ueda, Makoto Uchino
Ann Rehabil Med 2022;46(5):263-273.   Published online October 31, 2022
DOI: https://doi.org/10.5535/arm.22014
Objective
To clarify the profile of cognitive dysfunction and the effects of intensive exercise in spinocerebellar degeneration (SCD).
Methods
We enrolled 60 healthy controls and 16 patients with purely cerebellar type SCD without gait disturbance or organic changes other than cerebellar changes. To assess cognitive function, we evaluated the participants using the Mini-Mental State Examination (MMSE), Frontal Assessment Battery (FAB), and Montreal Cognitive Assessment-Japanese (MoCA-J) at admission and after intensive exercise.
Results
Compared to the controls, SCD patients showed significant cognitive decline. As a result of intensive exercise, significant improvements in motor and cognitive functions were observed: the MMSE score improved from 27.7±1.9 to 29.0±1.3 points (p<0.001); the FAB score improved from 14.8±2.2 to 15.8±2.0 points (p=0.002); and the MoCA-J score improved from 24.6±2.2 to 26.7±1.9 points (p<0.001). For sub-scores, significant improvements were noted in serial 7, lexical fluency, motor series, and delayed recall.
Conclusion
Our study indicates that intensive exercise can be effective not only for motor dysfunction but also for cognitive dysfunction (Clinical Trial Registration No. UMIN-CTR: UMIN000040079).

Citations

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  • Exercise and cognition in people with degenerative cerebellar ataxia: a narrative review
    Chelsea E. Macpherson, Meghan Bjalme-Evans, Fatima Awad, Sheng-Han Kuo, Lori Quinn
    Neurodegenerative Disease Management.2026; 16(1): 81.     CrossRef
  • Home-based Hybrid Assistive Limb Lumbar Type Telerehabilitation in Spinocerebellar Ataxias: A Nonrandomized Open-label Trial
    Yoshiyuki Kishimoto, Shinichiro Yamada, Atsushi Hashizume, Daisuke Ito, Shota Komori, Takahiro Kawase, Ayano Kondo, Yu Mori, Kazuki Obara, Munetaka Yamamoto, Yachiyo Kuwatsuka, Masahiko Ando, Tomokazu Abe, Yoshihiro Yasunaga, Masahisa Katsuno
    The Cerebellum.2025;[Epub]     CrossRef
  • 7,805 View
  • 104 Download
  • 2 Web of Science
  • 2 Crossref

Cardiopulmonary rehabilitation

Accuracy and Validity of Commercial Smart Bands for Heart Rate Measurements During Cardiopulmonary Exercise Test
Chul Kim, Seung Hyoun Kim, Mi Rim Suh
Ann Rehabil Med 2022;46(4):209-218.   Published online August 31, 2022
DOI: https://doi.org/10.5535/arm.22050
Objective
To assess the accuracies and validities of popular smart bands for heart rate (HR) measurement in cardiovascular disease (CVD) patients during a graded exercise test (GXT).
Methods
Seventy-eight patients were randomly assigned to wear two different smart bands out of three possible choices: Samsung Galaxy Fit 2, Xiaomi Mi Band 5, or Partron PWB-250 on each wrist. A 12-lead exercise electrocardiogram (ECG) and patch-type single-lead ECG were used to assess the comparative HR accuracy of the smart bands. The HR was recorded during the GXT using the modified Bruce protocol.
Results
The concordance correlation coefficients (rc) were calculated to provide a measure of agreement between each device and the ECG. In all conditions, the Mi Band 5 and Galaxy Fit 2’ correlations were rc>0.90, while the PWB-250 correlation was rc=0.58 at rest. When evaluating the accuracy according to the magnitude of HR, all smart bands performed well (rc>0.90) when the HR was below 100 but accuracy tended to decrease with higher HR values.
Conclusion
This study showed that the three smart bands had a high level of accuracy for HR measurements during low-intensity exercise. However, during moderate-intensity and high-intensity exercise, all the three smart bands performed less accurately. Further studies are needed to find a more optimal smart band for HR measurement that can be used for precise HR monitoring during formal cardiac rehabilitation exercise training, including at high and maximal intensity (Clinical Trial Registration No. cris.nih.go.kr/KCT0007036).

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    Marcello Sicbaldi, Laura Bartoli, Jose Albites-Sanabria, Ilaria D’Ascanio, Alessandro Silvani, Lorenzo Chiari, Alberto Camon, Luca Palmerini
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    Xiaoxue Gao, Jincheng Zhao, Tongkai Zhao, Yong-Gwan Song, Yuyao Zhi, Xinyi He
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    Rosa María Ortiz-Gutiérrez, José Javier López-Marcos, José Luis Maté-Muñoz, Paloma Moreta-de-Esteban, Patricia Martín-Casas
    Sensors.2025; 25(8): 2621.     CrossRef
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    Kazufumi Kitagaki, Yuji Hongo, Rie Futai, Takeshi Hasegawa, Hiroshi Morikawa, Hisashi Shimoyama
    JMIR Cardio.2025; 9: e77911.     CrossRef
  • İŞE BAĞLI DİNLENME SÜRELERİNİN MAKİNE ÖĞRENMESİ İLE TAHMİN EDİLMESİ
    Melis Türksever, Emin Kahya, N. Fırat Özkan
    Endüstri Mühendisliği.2025; 36(3): 367.     CrossRef
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    Chul Kim, Jun Hyeong Song, Seung Hyoun Kim
    Annals of Rehabilitation Medicine.2024; 48(4): 249.     CrossRef
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    Cailbhe Doherty, Rory Lambe, Ben O’Grady, Diarmuid O’Reilly-Morgan, Barry Smyth, Aonghus Lawlor, Neil Hurley, Elias Tragos
    JMIR mHealth and uHealth.2024; 12: e49443.     CrossRef
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    Irene Ferrando-Terradez, Lirios Dueñas, Ivana Parčina, Nemanja Ćopić, Svetlana Petronijević, Gianfranco Beltrami, Fabio Pezzoni, Constanza San Martín-Valenzuela, Maarten Gijssel, Stefano Moliterni, Panagiotis Papageorgiou, Yelko Rodríguez-Carrasco
    Healthcare.2023; 11(9): 1279.     CrossRef
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  • 8 Crossref

Pain & Musculoskeletal rehabilitation

Objective
To investigate the association of trunk fat and muscle composition, lumbar disc space narrowing, and low back pain in middle-aged farmers.
Methods
Fat and muscle areas were identified using standard Hounsfield unit ranges for adipose tissue and skeletal muscle with computed tomography images at the mid-L4 vertebral level. Trunk fat mass, muscle mass, and fat/muscle mass ratio were calculated. Low back pain was assessed using the Oswestry Disability Index (ODI). The L4/5-disc space and low back pain were also assessed.
Results
Male had a higher total trunk, back, psoas, and abdominal muscle mass, and visceral fat; female had a higher subcutaneous fat mass and fat/muscle ratio. Pearson correlation coefficients with ODI for waist circumference, total fat mass, visceral fat mass, and fat/muscle ratio were all significant in female; only the fat/muscle ratio was significant in male. Pearson correlation coefficients with L4/5-disc space narrowing grades for visceral fat mass, total, back, and psoas muscle mass, and fat/muscle ratio, were all significant in female; total and back muscle mass, and fat/muscle ratio in male.
Conclusion
There were significant relationships between: fat indicators with low back pain; trunk muscle mass with lumbar disc degeneration; and fat/muscle ratio with both lumbar disc degeneration and low back pain. The fat/muscle ratio may be a useful index for low back pain.

Citations

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  • Causal associations between abdominal obesity, dietary patterns, and intervertebral disc degeneration: a bidirectional two-sample Mendelian randomization study with clinical validation
    YiTing Wang, JiaoYi Pan, ZhongHao Dai, BaiTong Zhao, XingYong Mao, GuoYu Ling, ZiTong Zhang, ZeZhong Liu, Xu Wang, Bing Xu
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    Dong Hyun Kim, Yoon-Hee Choi, JooHee Lee, Sang Yoon Lee
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    Barbara Rosolek, Dan Iulian Alexe, Krystyna Gawlik, Elena Adelina Panaet, Ilie Mihai, Bogdan Alexandru Antohe, Anna Zwierzchowska
    Healthcare.2025; 13(9): 1054.     CrossRef
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    Ruchi Basista, Deepika Singla, Abhinav Jain
    Journal of Chiropractic Medicine.2025; 24(1-4): 318.     CrossRef
  • Association of Body Mass Index and Central Obesity with Spinopelvic Alignment Parameters in a Chinese Population: A Prospective Study
    Hao Qi, Zenghui Zhao, Feiyu Zu, Chenxi Wang, Chenchen Wang, Zuzhuo Zhang, Xiaonan Tian, Dan Su, Zhaoxuan Wang, Rui Xue, Zhiyong Hou, Wei Chen, Di Zhang
    World Neurosurgery.2024; 189: e153.     CrossRef
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    Rabia Mihriban Kilinc, Fatih İlker Can
    Cureus.2023;[Epub]     CrossRef
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    Marian Pop, Marius Mărușteri
    Diagnostics.2023; 13(11): 1913.     CrossRef
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    Myung Woo Park, Sang Jun Park, Sun Gun Chung
    Neurospine.2023; 20(3): 959.     CrossRef
  • Back Extensor Strength as a Potential Marker of Frailty Using Propensity Score Matching and Machine Learning
    Taewook Kim, Gowun Kim, Hee-won Park, Eun Kyoung Kang, Sora Baek
    Journal of Clinical Medicine.2023; 12(19): 6156.     CrossRef
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    Seungsu Jeong, Gowun Kim, Hee-won Park, Sora Baek
    Annals of Rehabilitation Medicine.2023; 47(6): 468.     CrossRef
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    Minjung Kook, Insuh Kim, Jeongyeon Seo, Hyundong Kim, Heesung Nam, Nami Han
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Cardiopulmonary rehabilitation

Is Age-Predicted Maximal Heart Rate Applicable in Patients With Heart or Lung Disease?
Sang Hun Han, Min Soo Choi, Young Mo Kim, Dong Min Kim, Ho Eun Park, Ji Won Hong, Sang Hun Kim, Yong Beom Shin, Byeong Ju Lee
Ann Rehabil Med 2022;46(3):133-141.   Published online June 30, 2022
DOI: https://doi.org/10.5535/arm.21181
Objective
To compare the predicted and actual maximal heart rate (HRmax) values in the cardiopulmonary exercise test (CPET).
Methods
We retrospectively investigated 1,060 patients who underwent a CPET between January 2016 and April 2020 at our institution’s cardiopulmonary rehabilitation center. The following patients were included: those aged >20 years, those tested with a treadmill, and those who underwent symptom-limited maximum exercise testing— reaching ≥85% of the predicted HRmax (62% if taking beta-blockers) and highest respiratory exchange ratio ≥1.1. Ultimately, 827 patients were included in this study. Data on diagnosis, history of taking beta-blockers, age, body mass index (BMI), and CPET parameters were collected. Subgroup analysis was performed according to age, betablockers, BMI (low <18.5 kg/m2, normal, and high ≥25 kg/m2), and risk classification.
Results
There was a significant difference between the actual HRmax and the predicted value (p<0.001). Betablocker administration resulted in a significant difference in the actual HRmax (p<0.001). There were significant differences in the moderate-to-high-risk and low-risk groups and the normal BMI and high BMI groups (p<0.001). There was no significant difference between the elderly and younger groups. We suggest new formulae for HRmax of cardiopulmonary patients: estimated HRmax=183-0.76×age (the beta-blocker group) and etimated HRmax=210-0.91×age (the non-beta-blocker group).
Conclusion
Age-predicted HRmax was significantly different from the actual HRmax of patients with cardiopulmonary disease, especially in the beta-blocker group. For participants with high BMI and moderate-tosevere risk, the actual HRmax was significantly lower than the predicted HRmax.

Citations

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  • MITO-VATION: Feasibility of a technology-supported structured home exercise program in Mitochondrial Disease
    Jeremey Thomas Horne, Natalie E. Allen, Serene S. Paul, Judith Walker, Carolyn Sue, Hisham Al-Obaidi
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  • Diagnosing chronotropic incompetence: a scoping review of current approaches and their application in a cardiac rehabilitation cohort
    Margot Vermeiren, Nore Primus, Kato Heyns, Véronique Cornelissen, Rik Willems, Tim Van Puyvelde, Joris Ector, Kaatje Goetschalckx, Peter Sinnaeve
    European Journal of Preventive Cardiology.2026;[Epub]     CrossRef
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    Yukun Liang, Mei Ma
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    Chul Kim, Hee-Eun Choi, Chin Kook Rhee, Jae Ha Lee, Ju Hyun Oh, Jun Hyeong Song
    Healthcare.2025; 13(3): 308.     CrossRef
  • Free-Living Physical Activity Energy Expenditure Based on Accelerometry Versus Heart Rate in Community-Dwelling Older Adults
    Joona Neuvonen, Timo Aittokoski, Timo Rantalainen, Jukka Lipponen, Lotta Palmberg, Soren Brage, Tomas I. Gonzales, Erja Portegijs, Taina Rantanen, Laura Karavirta
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    祥昊 付
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    Alessandra Amato, Patrizia Proia, Anna Alioto, Carlo Rossi, Andrea Pagliaro, Paolo Ragonese, Giuseppe Schirò, Giuseppe Salemi, Rosalia Caldarella, Sonya Vasto, Robert Nowak, Dorota Kostrzewa-Nowak, Giuseppe Musumeci, Sara Baldassano
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Spinal cord injury

Utilizing Pulmonary Function Parameters to Predict Dysphagia in Individuals With Cervical Spinal Cord Injuries
So Jung Lee, Sungchul Huh, Sung-Hwa Ko, Ji Hong Min, Hyun-Yoon Ko
Ann Rehabil Med 2021;45(6):450-458.   Published online December 31, 2021
DOI: https://doi.org/10.5535/arm.21161
Objective
To utilize pulmonary function parameters as predictive factors for dysphagia in individuals with cervical spinal cord injuries (CSCIs).
Methods
Medical records of 78 individuals with CSCIs were retrospectively reviewed. The pulmonary function was evaluated using spirometry and peak flow meter, whereas the swallowing function was assessed using a videofluoroscopic swallowing study. Participants were divided into the non-penetration-aspiration group (score 1 on the Penetration-Aspiration Scale [PAS]) and penetration-aspiration group (scores 2–8 on the PAS). Individuals with pharyngeal residue grade scores >1 were included in the pharyngeal residue group.
Results
The mean age was significantly higher in the penetration-aspiration and pharyngeal residue groups. In this study, individuals with clinical features, such as advanced age, history of tracheostomy, anterior surgical approach, and higher neurological level of injury, had significantly more penetration-aspiration or pharyngeal residue. Individuals in the penetration-aspiration group had significantly lower peak cough flow (PCF) levels. Individuals in the pharyngeal residue group had a significantly lower forced expiratory volume in 1 second (FEV1). According to the receiver operating characteristic curve analysis of PCF and FEV1 on the PAS, the cutoff value was 140 L/min and 37.5% of the predicted value, respectively.
Conclusion
Low PCF and FEV1 values may predict the risk of dysphagia in individuals with CSCIs. In these individuals, active evaluation of swallowing is recommended to confirm dysphagia.

Citations

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  • Clinical Predictors of Dysphagia in Acute and Subacute Traumatic Cervical Spinal Cord Injury: A Retrospective Observational Study
    Yong Beom Shin, Jin A Yoon, Byeong Ju Lee, Myung Hun Jang, Hyuk Jin Choi, Sang Hun Kim
    Dysphagia.2026; 41(1): 149.     CrossRef
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    Ryo Tagaino, Kana Saijo, Naru Shiraishi, Takamasa Komiyama, Kuniyuki Izumita, Takuma Hisaoka, Ai Hirano, Jun Ota, Yukio Katori, Toru Ogawa, Keiichi Sasaki, Nobuhiro Yoda, Hiroshi Egusa, Shigeto Koyama
    Journal of Oral Rehabilitation.2026; 53(7): 1296.     CrossRef
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    Roberta ZUPO, Beatrice POGGI, Nicole CAGGIANO, Giulio VARRONE, Fabio CASTELLANA, Silvia NATOLI, Rodolfo SARDONE, Antonio NARDONE, Chiara PAVESE
    European Journal of Physical and Rehabilitation Medicine.2025;[Epub]     CrossRef
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    Su Ji Lee, Ji Cheol Shin
    Spinal Cord.2024; 62(1): 42.     CrossRef
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    Jin-Woo Choi, Dae Yeong Kim, Sun Young Joo, Donghwi Park, Min Cheol Chang
    Frontiers in Neurology.2024;[Epub]     CrossRef
  • Coordination Between Respiration and Swallowing in Patients With Dysphagia After Cervical Spinal Cord Injury: An Observational Case–Control Study
    Xuluan Xu, Qingsu Zhang, Yongqi Xie, Degang Yang, Feng Gao, Yongxue Yuan, Yu Zhang, Jianjun Li
    American Journal of Speech-Language Pathology.2024; 33(5): 2572.     CrossRef
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    Amalia Nanjarí R , María del Carmen Campos
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    Laura Pitts, Valerie K. Hamilton, Erin A. Walaszek, Stephanie Watts, Leora R. Cherney
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  • Association between Anterior Surgical Approach and Dysphagia Severity in Patients with Cervical Spinal Cord Injury
    Min Cheol Chang, Dae Yeong Kim, Jin-Woo Choi, Ho Yong Choi, Jin-Sung Park, Donghwi Park
    Journal of Clinical Medicine.2023; 12(9): 3227.     CrossRef
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    Yoshinori Maki, Mayumi Takagawa, Akio Goda, Junichi Katsura, Ken Yanagibashi
    Cureus.2023;[Epub]     CrossRef
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    Teresa Pitts, Kimberly E. Iceman, Alyssa Huff, M. Nicholas Musselwhite, Michael L. Frazure, Kellyanna C. Young, Clinton L. Greene, Dena R. Howland
    Journal of Neurophysiology.2022; 128(2): 405.     CrossRef
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  • 147 Download
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  • 11 Crossref

Dysphagia

Peak Voluntary Cough Flow and Oropharyngeal Dysphagia as Risk Factors for Pneumonia
Jayoon Choi, Sora Baek, Gowun Kim, Hee-won Park
Ann Rehabil Med 2021;45(6):431-439.   Published online December 31, 2021
DOI: https://doi.org/10.5535/arm.21068
Objective
To investigate the relationship between voluntary peak cough flow (PCF), oropharyngeal dysphagia, and pneumonia in patients who were evaluated with videofluoroscopic swallowing study (VFSS).
Methods
Patients who underwent both VFSS and PCF measurement on the same day were enrolled retrospectively (n=821). Pneumonia (n=138) and control (n=683) groups were assigned based on presence of pneumonia within 1 month from the date of VFSS assessment. In addition, sex, age (<65 and ≥65 years), preceding conditions, modified Barthel Index (MBI), Mini-Mental State Examination (MMSE), PCF value (<160, ≥160 and <270, and ≥270 L/min), and presence of aspiration/penetration on VFSS were reviewed.
Results
Pneumonia group was more likely to be male (n=108; 78.3%), ≥65 years (n=121; 87.7%), with neurodegenerative (n=25; 18.1%) or other miscellaneous diseases (n=50; 36.2%), and in poor functional level with lower value of MBI (39.1±26.59). However, MMSE was not significantly different in comparison to that of the control group. The pneumonia group was also more likely to have dysphagia (82.6%) and lower value of PCF (<160 L/min, 70.3%). In multivariable logistic regression analysis, male sex (odd ratio [OR]=6.62; 95% confidence interval [CI], 2.70–16.26), other miscellaneous diseases as preceding conditions (OR=2.52; 95% CI, 1.14–5.58), dysphagia (OR=3.82; 95% CI, 1.42–10.23), and PCF <160 L/min (OR=14.34; 95% CI, 1.84–111.60) were factors significantly related with pneumonia.
Conclusion
Impaired swallowing and coughing function showed an independent association with the development of pneumonia. Patients with PCF <160 L/min require more attention with lung care and should be encouraged with voluntary coughing strategy to prevent possible pulmonary complications.

Citations

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  • Peak cough flow and diaphragmatic excursion during coughing in stroke patients with tracheostomy: a cross-sectional study
    Dan Li, Pengfei Yao, Juan Wang, Yulong Wang
    Topics in Stroke Rehabilitation.2026; 33(5): 542.     CrossRef
  • Voluntary peak cough flow: A simple and effective tool to predict dysphagia across diverse etiologies
    Hakan Gölaç, Güzide Atalık, Adnan Gülaçtı, Ebru Şansal, Banu Tijen Ceylan, Metin Yılmaz
    European Archives of Oto-Rhino-Laryngology.2026; 283(3): 1869.     CrossRef
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    Lucas DM, Peterson R, Rieck J, Owusu M, McNally E, Scheel R, Cavanagh P, Langmore S, Kearney A, Levitt J, Siner J, Vojnik R, Warner H, Sakharkar M, Liu W, Rubio A, Moss M, Krisciunas GP
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    Monique Messaggi-Sartor, Anna Guillén-Solà, David Blanco, Ester Marco
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    Dong-Yeon Kang
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    Frontiers in Aging.2025;[Epub]     CrossRef
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    Corinne A Jones, Maggie-Lee Huckabee, Georgia A Malandraki, David Paydarfar
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    Tatsuya Morishita, Shusuke Toyama, Kazuaki Suyama, Fumiya Nagata, Masatoshi Itaki, Takako Tanaka, Shuntaro Sato, Yuji Ishimatsu, Terumitsu Sawai, Ryo Kozu
    Archives of Physical Medicine and Rehabilitation.2024; 105(11): 2062.     CrossRef
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    Mónica Zapata-Soria, Irene Cabrera-Martos, Alejandro Heredia-Ciuró, Esther Prados-Román, Javier Martín-Nuñez, Marie Carmen Valenza
    Journal of Clinical Medicine.2024; 13(18): 5547.     CrossRef
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    Back Min Oh, Hyun Seok, Sang-Hyun Kim, Seung Yeol Lee, Su Jung Park, Beom Jin Kim, Hyun Jung Kim
    Annals of Rehabilitation Medicine.2023; 47(3): 192.     CrossRef
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    Takashi Asakawa, Mieko Ogino, Naomi Tominaga, Naoto Ozaki, Jin Kubo, Wataru Kakuda
    Neurology International.2023; 15(4): 1227.     CrossRef
  • 9,290 View
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  • 16 Web of Science
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Geriatric Rehabilitation

Efficacy of an Integrated Training Device in Improving Muscle Strength, Balance, and Cognitive Ability in Older Adults
Choong-Hee Roh, Da-Sol Kim, Gi-Wook Kim, Yu-Hui Won, Sung-Hee Park, Jeong-Hwan Seo, Myoung-Hwan Ko
Ann Rehabil Med 2021;45(4):314-324.   Published online August 30, 2021
DOI: https://doi.org/10.5535/arm.21072
Objective
To determine the effects of an integrated training device for strength and balance on extremity muscle strength, postural balance, and cognition in older adults using a combination with various rehabilitation training games, in which balance, strength, and cognitive training were configured in a single device.
Methods
This prospective study included 20 healthy participants aged 65–85 years. Participants trained for 30 minutes daily, 3 days weekly, for 6 weeks with an integrated training device for strength and balance (SBT-120; Man&Tel Inc., Gumi, Korea). Main outcomes were measured using the Korean Mini-Mental State Examination (K-MMSE), Korean version of the Montreal Cognitive Assessment (K-MoCA), Timed Up and Go Test (TUG), Functional Reach Test (FRT), Berg Balance Scale (BBS), and Manual Muscle Test. Measurements were taken at three time points: T0 (pretreatment), T1 (immediately after treatment), and T2 (4 weeks after treatment).
Results
All 20 patients completed the training, and TUG, FRT, and BBS scores significantly improved at T1 and T2 compared to T0. Mean TUG scores decreased by 0.99±2.00 at T1 and 1.05±1.55 at T2 compared to T0. Mean FRT scores increased by 6.13±4.26 at T1 and 6.75±4.79 at T2 compared to T0. BBS scores increased by 0.60±0.94 at T1 and 0.45±1.15 at T2 compared to T0. Moreover, muscle strength and cognition (K-MMSE and K-MoCA scores) increased after training.
Conclusion
Our findings suggest that an integrated training device for strength and balance can be a safe and useful tool for older adults.

Citations

Citations to this article as recorded by  
  • Effects of Comprehensive Activity Training Program on Cognitive and Physical Abilities Among Older Adults with Mild Cognitive Impairment
    Chutima Thongwachira, Teeranut Harnirattisai, Diana Morris
    The Journal of Behavioral Science.2025; 20(1): 30.     CrossRef
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  • 130 Download
  • 1 Web of Science
  • 1 Crossref

Pain & Musculoskeletal rehabilitation

The Association Between Sagittal Plane Alignment and Disc Space Narrowing of Lumbar Spine in Farmers
Ki Hoon Park, Sora Baek, Eun Kyoung Kang, Hee-won Park, Gowun Kim, Sung Hyun Kim
Ann Rehabil Med 2021;45(4):294-303.   Published online August 30, 2021
DOI: https://doi.org/10.5535/arm.21037
Objective
To investigate whether lumbar lordosis (LL) and lumbar segmental lordosis (LSL) are related to sex, age, low back pain (LBP), and lumbar disc space narrowing (DSN).
Methods
A total of 569 farmers were recruited. In lateral spine radiograph, LL (L1–L5) and LSL (L1, L2, L3, L4, and L5) were measured using Cobb’s method. The differences in LSL values (ΔLSL) according to the presence or absence of a DSN were calculated as LSLDSN – LSLnoDSN for each DSN level.
Results
In male, the lateral spine radiograph showed significantly greater L4-LSL and L5-LSL and smaller L1-LSL and L2-LSL compared to female. LLs in the 50–59 and ≥60 years age groups were significantly smaller compared to those in the <50 years age group. In subjects with LBP, LL and L4-LSL were significantly smaller than in those without. The ΔLSLs at the disc level with DSN showed the greatest decrease: L1-ΔLSL (Δ-3.99°), L2-ΔLSL (Δ-3.31°), L3-ΔLSL (Δ-2.87°), L4-ΔLSL (Δ-3.31°), and L5-ΔLSL (Δ-4.44°) in L1/2, L2/3, L3/4, L4/5, and L5/S1 DSN, respectively. Conversely, distant ΔLSLs were inversely increased: L1-LSL (Δ0.75°) with L4/5 DSN and L2-LSL (Δ0.94°) with L5/S1 DSN.
Conclusion
Sagittal plane alignment was significantly associated with sex, age, LBP, and DSN. LSLs around the levels of DSN were decreased, and there was compensational increase of LSL distant to the DSN to maintain the overall LL.

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  • Segmental asymmetry and multiplanar motion of the lumbar spine: Cadaveric insights into spinal pathologies
    Asghar Rezaei, Alexander Hooke, Babak Dashtdar, Areonna Schreiber, Abdelrahman M. Hamouda, Kai-Nan An, Benjamin Elder, Kenton Kaufman, Lichun Lu
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    Hong Ren, Nan Lin, Peng Zhao, Huizhi Han, Hui Zhao, Lianxiang Xiao, Mimi Tian, Xiangtao Lin
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    Jinheum Kim, Kanwoo Youn, Jinwoo Park
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    Minjung Kook, Insuh Kim, Jeongyeon Seo, Hyundong Kim, Heesung Nam, Nami Han
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  • 7 Web of Science
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Review Article

Cardiopulmonary rehabilitation

Effectiveness of Inspiratory Muscle Training on Respiratory Muscle Strength in Patients Undergoing Cardiac Surgeries: A Systematic Review With Meta-Analysis
Fiona Verdine Dsouza, Sampath Kumar Amaravadi, Stephen Rajan Samuel, Harish Raghavan, Nagaraja Ravishankar
Ann Rehabil Med 2021;45(4):264-273.   Published online August 30, 2021
DOI: https://doi.org/10.5535/arm.21027
To determine the effect of inspiratory muscle training (IMT) on pulmonary function, respiratory muscle strength (RMS), and functional capacity in patients undergoing cardiac surgery. The PubMed, PEDro, CINAHL, Web of Science, CENTRAL, and EMBASE databases were searched from inception to June 2020. Randomized controlled trials (RCTs) that evaluated patients who underwent cardiac surgery were included in this review. Meta-analysis performed using a random-effects model showed that the mean difference in forced vital capacity, forced expiratory volume in 1 second, 6-minute walk distance, and RMS was 3.47% (95% confidence interval [CI], 0.57 to 6.36), 5.80% (95% CI, 2.03 to 9.56), 78.05 m (95% CI, 60.92 to 95.18), and 4.8 cmH2O (95% CI, -4.00 to 13.4), respectively. There is strong evidence that IMT improves inspiratory muscle strength, pulmonary function, and functional capacity, and reduces the length of hospital stay in patients undergoing cardiac surgery.

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    Arnengsih Nazir
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    Hanifa Suleman, Zohaib Shahid, Muhammad Naveed Babur, Abdul Wadood, Khizar Abid, Muhammad Ali Khan, Asna Waseem
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    Clênia Oliveira Araújo, Carla Cristina Araújo Alves, Francisco R A dos Santos, Lawrence P Cahalin, Graziella França Bernardelli Cipriano, Gerson Cipriano
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    Sisi Zhang, Bo Li, Xiaoping Meng, Houjuan Zuo, Dayi Hu
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    Danielle L. Kirkman, Duck-chul Lee, Salvatore Carbone
    Progress in Cardiovascular Diseases.2022; 70: 66.     CrossRef
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    E. D. Bazdyrev, N. A. Terentyeva, N. A. Galimova, K. E. Krivoshapova, O. L. Barbarash
    Rational Pharmacotherapy in Cardiology.2022; 18(4): 393.     CrossRef
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Original Articles

Physical Therapy

Combined Effects of Extracorporeal Shockwave Therapy and Integrated Neuromuscular Inhibition on Myofascial Trigger Points of Upper Trapezius: A Randomized Controlled Trial
Dina Al-Amir Mohamed, Ragia Mohamed Kamal, Manal Mohamed Gaber, Yasser M. Aneis
Ann Rehabil Med 2021;45(4):284-293.   Published online August 30, 2021
DOI: https://doi.org/10.5535/arm.21018
Objective
To investigate the combined effect of extracorporeal shockwave therapy (ESWT) and integrated neuromuscular inhibition (INI) on myofascial trigger points in the upper trapezius.
Methods
Sixty subjects aged 18–24 years old with active myofascial trigger points in the upper trapezius were studied. Participants were assigned randomly to either group A who received ESWT one session/week, group B who received INI three sessions/week, or group C who received ESWT in addition to INI. All groups completed 4 weeks of intervention. The following main outcome measures were evaluated at baseline and after 4 weeks of intervention: pain intensity, functional disability, pressure pain threshold (PPT), sympathetic skin response (SSR), and neuromuscular junction response (NMJR).
Results
Within-group analysis revealed a significant decline in visual analog scale (VAS), Arabic neck disability index (ANDI), and NMJR and incline in PPT and SSR latency post-intervention (p<0.001). Multiple comparison analysis showed a substantial difference between the groups, while the major changes favored group C (p<0.05).
Conclusion
Combined treatment with ESWT and INI for treating myofascial trigger points in the upper trapezius is more effective than using only one of the two approaches in terms of clinical, functional, and neurophysiological aspects.

Citations

Citations to this article as recorded by  
  • Effect of integrated neuromuscular inhibition technique on subjects with neck pain and forward head posture: a randomized controlled trial
    Rania Reffat Ali, Somaya Nady Mohamed Elsayed, Ragia Mohamed Kamel, Ebtisam Mohamed Fahmy, Hend Ahmed Hamdy
    Journal of Manual & Manipulative Therapy.2025; 33(5): 401.     CrossRef
  • Electrostatic electricity of wool fabrics as a novel therapeutic approach for neuropathic pain relief
    Hussien S. A. Meabed, Rehab Elanwar, Hanan Hosny, Marwa A. Elgaly, Manal M. Gaber, T. A. Aya Ewais, Mohamed Fareed Mehleb, Reem M. Sabry
    The Egyptian Journal of Neurology, Psychiatry and Neurosurgery.2025;[Epub]     CrossRef
  • Therapeutic effect of focused-extracorporeal shockwave therapy on muscular and adjacent tissue stiffness and pain changes in myofascial pain syndrome: A randomized controlled trial study
    Pijakkana Vasvit, Kultida Klarod, Oranat Sukkho, Sirirat Kiatkulanusorn, Phurichaya Werasirirat, Xue-Qiang Wang, Yong-Hui Zhang, Juntip Namsawang, Pornpimol Muanjai, Nongnuch Luangpon
    Complementary Therapies in Medicine.2025; 92: 103203.     CrossRef
  • Efficacy of Integrated Neuromuscular Inhibition Versus Postisometric Relaxation Technique on Rhomboid Latent Myofascial Trigger Points: A Randomized Clinical Trial
    Aliaa M. Elabd, Omar M. Elabd, Waleed T. Mansour, Radwa F. Hammam
    Journal of Manipulative and Physiological Therapeutics.2025; 48(1-5): 214.     CrossRef
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    Hannes Müller-Ehrenberg, Jacopo Bonavita, Yunfeng Sun, Carla Stecco, Federico Giordani
    Life.2025; 15(10): 1501.     CrossRef
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    Radwa F. Hammam, Ahmed M. Alshimy, Omar M. Elabd, Aliaa M. Elabd
    American Journal of Physical Medicine & Rehabilitation.2024; 103(11): 1000.     CrossRef
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    Melissa Nahomi Kuroda, Guilherme Thomaz de Aquino Nava, Caroline Baldini Prudencio, Daiane Affonso Paulo, Isadora Peixouto, Maiki Yoshi Moroshima, Mariana de Almeida Lourenço, Caroline Nogueira da Silva, Angélica Mércia Pascon Barbosa, Cristiane Rodrigues
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    Maren Reger, Sabine Kutschan, Maren Freuding, Thorsten Schmidt, Lena Josfeld, Jutta Huebner
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    Pankaj Verma, Deepak Kumar Pradhan, Sandeep Singh
    Bulletin of Faculty of Physical Therapy.2022;[Epub]     CrossRef
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    Hessa Al Shehhi, Mouza Lootah, Ibrahim Moustafa, Tamer Shousha
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    Chang Han Lee, Shi-Uk Lee
    Annals of Rehabilitation Medicine.2021; 45(4): 261.     CrossRef
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  • 9 Web of Science
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Cardiopulmonary rehabilitation

Do Patients Maintain Proper Long-Term Cardiopulmonary Fitness Levels After Cardiac Rehabilitation? A Retrospective Study Using Medical Records
Chul Kim, Hee Eun Choi, Jin Hyuk Jang, Jun Hyeong Song, Byung-Ok Kim
Ann Rehabil Med 2021;45(2):150-159.   Published online April 30, 2021
DOI: https://doi.org/10.5535/arm.20123
Objective
To examine whether patients who participated in a cardiac rehabilitation (CR) program after hospitalization for acute coronary syndrome maintained cardiorespiratory fitness (CRF) in the community.
Methods
We conducted a retrospective study including 78 patients who underwent percutaneous coronary intervention or coronary artery bypass graft surgery at our hospital’s cardiovascular center and participated in a CR program and a 5-year follow-up evaluation. Patients were divided into a center-based CR (CBCR) group, participating in an electrocardiography-monitored exercise training in a hospital setting, and a home-based CR (HBCR) group, receiving aerobic exercise training and performed self-exercise at home.
Results
No significant differences were found between groups (p>0.05), except the proportion of non-smokers (CBCR 59.5% vs. HBCR 31.7%; p=0.01). In both groups, the maximal oxygen consumption (VO2max) increased significantly during the first 12 weeks of follow-up and remained at a steady state for the first year, but it decreased after the 1-year follow-up. Particularly, VO2max at 5 years decreased below the baseline value in the HBCR group. In the low CRF group, the CRF level significantly improved at 12 weeks, peaked at 1 year, and was still significantly different from the baseline value after 5 years. The high CRF group did not show any significant increase over time relative to the baseline value, but most patients in the high CRF group maintained relatively appropriate CRF levels after 5 years.
Conclusion
Continuous support should be provided to patients to maintain optimal CRF levels after completing a CR program.

Citations

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    Kariann R. Drwal, Bonnie J. Wakefield, Adrienne Wagenblast, Delanie Hurst, Bjarni Haraldsson, Ramzi N. El Accaoui
    Journal of Cardiopulmonary Rehabilitation and Prevention.2026; 46(1): 44.     CrossRef
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    Chul Kim, Jun Hyeong Song, Seung Hyoun Kim
    Annals of Rehabilitation Medicine.2024; 48(4): 249.     CrossRef
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    Chul Kim, Seok Hyeon Lee
    Annals of Rehabilitation Medicine.2023; 47(4): 272.     CrossRef
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    Ki-Hong Kim, Jae-Young Han
    Annals of Rehabilitation Medicine.2023; 47(5): 318.     CrossRef
  • 7,638 View
  • 134 Download
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Brain disorders

Correlation of Videofluoroscopic Swallowing Study Findings With Radionuclide Salivagram in Chronic Brain-Injured Patients
Ga Yang Shim, Ju Sun Oh, Seunghee Han, Kyungyeul Choi, Son Mi Lee, Min Woo Kim
Ann Rehabil Med 2021;45(2):108-115.   Published online April 21, 2021
DOI: https://doi.org/10.5535/arm.20171
Objective
To investigate the correlation between videofluoroscopic swallowing study (VFSS) and radionuclide salivagram findings in chronic brain-injured patients with dysphagia.
Methods
Medical records of chronic brain-injured patients who underwent radionuclide salivagram and VFSS were retrospectively analyzed. Patients were divided into two groups according to salivagram findings. Differences in patient characteristics and clinical factors, including Mini-Mental State Examination (MMSE), Modified Barthel Index (MBI), Functional Ambulatory Category (FAC), feeding method, tracheostomy state, and VFSS findings between the two groups were investigated.
Results
A total of 124 patients were included in this study. There were no significant differences in MMSE, MBI, FAC, feeding method, and presence of tracheostomy between the two groups. However, the incidence of aspiration pneumonia history was significantly higher in the positive salivagram group. The Functional Dysphagia Scale (FDS) was significantly associated with positive salivagram findings, especially in the pharyngeal phase. A multivariate logistic regression analysis showed that laryngeal elevation and epiglottic closure was statistically significant FDS parameter in predicting salivary aspiration on a salivagram (odds ratio=1.100; 95% confidence interval, 1.017–1.190; p=0.018). The receiver operating characteristic (ROC) curve of FDS in the pharyngeal phase showed that an optimum sensitivity and specificity of 55.1% and 65.4%, respectively, when the cut-off value was 39.
Conclusion
In chronic brain-injured patients, inappropriate laryngeal elevation and epiglottic closure is predictive variable for salivary aspiration. Therefore, performing a radionuclide salivagram in patients with FDS of 39 or less in the pharyngeal phase for prevents aspiration pneumonia from salivary aspiration.

Citations

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  • Correlation Between Clinical Characteristics and Radionuclide Salivagram Findings in Infants With Congenital Laryngeal Developmental Anomalies
    Yun Liu, Xue Wang, Li-bo Wang, Xin-rong Sun
    Journal of Voice.2025; 39(6): 1597.     CrossRef
  • Understanding the Drooling Evaluation
    Kyoung-chul Min, Sang-min Seo, Hee-soon Woo
    Journal of the Korean Dysphagia Society.2022; 12(2): 85.     CrossRef
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  • 131 Download
  • 1 Web of Science
  • 2 Crossref

Dysphagia

Predictors of Aspiration Pneumonia in the Elderly With Swallowing Dysfunction: Videofluoroscopic Swallowing Study
Joo Young Ko, Dae Youp Shin, Tae Uk Kim, Seo Young Kim, Jung Keun Hyun, Seong Jae Lee
Ann Rehabil Med 2021;45(2):99-107.   Published online April 14, 2021
DOI: https://doi.org/10.5535/arm.20180
Objective
To identify the variables of videofluoroscopic swallowing study (VFSS) that are useful for predicting the risk of aspiration pneumonia in elderly patients with dysphagia.
Methods
A total of 251 patients (aged 65 years or more) were included and divided into a pneumonia group (n=133) and a non-pneumonia group (n=118). The pneumonia group included patients who had been diagnosed with aspiration pneumonia, and individuals in the non-pneumonia group did not have pneumonia but were referred for VFSS. The medical records and results of VFSS were reviewed and compared between the groups retrospectively.
Results
The pneumonia group exhibited a male preponderance and a higher 8-point Penetration-Aspiration Scale (8PPAS) score. The mean values of 8PPAS score for swallowing thick liquid and rice porridge was significantly higher in the pneumonia group. The pharyngeal delay time (PDT) and pharyngeal transit time (PTT) were significantly longer in the pneumonia group. The amounts of vallecular and pyriform sinus residue were increased in the pneumonia group. The delay in swallowing reflex and the decrease in laryngeal elevation were more frequently observed in the pneumonia group. Among those variables, PDT and PTT were identified as significant predictors of aspiration pneumonia based on logistic regression analysis.
Conclusion
The present study delineated the findings of VFSS, suggesting an increased risk of aspiration pneumonia in elderly patients with dysphagia. The results demonstrate that prolonged PDT and PTT are significant predictors of aspiration pneumonia.

Citations

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  • Clinical Predictors of Dysphagia in Acute and Subacute Traumatic Cervical Spinal Cord Injury: A Retrospective Observational Study
    Yong Beom Shin, Jin A Yoon, Byeong Ju Lee, Myung Hun Jang, Hyuk Jin Choi, Sang Hun Kim
    Dysphagia.2026; 41(1): 149.     CrossRef
  • Pneumonia in frail older adults: from diagnosis to optimized management
    Kosaku Komiya, Yuki Yoshimatsu, Akihiko Hagiwara, Ryohei Kudoh, Hisayuki Shuto, Izumi Yamatani, Akihiko Goto
    Journal of Infection and Chemotherapy.2026; 32(2): 102914.     CrossRef
  • Association Between Findings on Videofluoroscopic Swallowing Studies and Pneumonia Onset in Residents of Elderly Care Facilities
    Takafumi Yamano, Ryusei Nuita, Kensuke Kawamoto, Fumitaka Omori, Kaori Wada, Miho Tanaka
    Cureus.2026;[Epub]     CrossRef
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    Wei-Kai Chuang, Bing-Fong Lin, Yu-Hao Lee, Po-Hsun Su, Yung-Shuo Kao, Chia-Feng Lu
    Archives of Physical Medicine and Rehabilitation.2026;[Epub]     CrossRef
  • Lactoferrin–chitosan composite hydrogel: a dysphagia-oriented carrier for sustained ergothioneine delivery
    Ziang Tian, Ling Liu, Hanyuan Luo, Xiaojuan Lei, Jichun Zhao, Lin Lei, Zhigang Xu, Kaihong Zeng, Jian Ming
    Food Research International.2026; 237: 119228.     CrossRef
  • Clinical Profile of Outpatients Undergoing Swallowing Evaluation and Its Association with Pneumonia History: A Videofluoroscopic Study
    Ayşe Kübra Söyler, Numan Demir, Selen Serel Arslan, Inci Nur Saltik-Temizel, Ömer Faruk Yaşaroğlu, Hasan Erkan Kilinç, Aynur Ayşe Karaduman
    Journal of Clinical Medicine.2026; 15(8): 2990.     CrossRef
  • Association Between Masticatory Difficulty and Chronic Cough in a Korean Population
    Chang Wan Kim, Tae Sic Lee, Chun Sung Byun, Yon Chul Park
    International Dental Journal.2025; 75(2): 496.     CrossRef
  • Research on Intelligent Diagnosis Method of Swallowing Signal Based on Complex Electrical Impedance Myography
    Xu Chu, Shaoshuai Yu, Fu Zhang, Yuxiang Yang, Letian Fu, Qi Liu
    IEEE Sensors Journal.2025; 25(4): 5969.     CrossRef
  • The Brain Lesion Affecting Dysphagia in Patient with Supratentorial Stroke
    Jeon-Woong Kang, Seong-Hoon Lim, Dae-Hyun Jang, Min-Wook Kim, Jaewon Kim
    NeuroRehabilitation: An International, Interdisciplinary Journal.2025; 56(3): 340.     CrossRef
  • Predictors of Pneumonia in Patients With Penetration-Aspirations Detected on Fiberoptic Endoscopic Evaluation of Swallowing
    Raviv Allon, Elad Babayof, Yonatan Lahav, Yael Shapira-Galitz
    Dysphagia.2025; 40(5): 1205.     CrossRef
  • Collaboration Between Acute Care Hospitals and Nursing Homes for Dysphagia Management: A Comparative Study of Patients With and Without Pneumonia-Related Hospitalization
    Takafumi Yamano, Shoichi Kimura, Fumitaka Omori, Kaori Wada, Miho Tanaka, Takashi Tsutsumi
    Cureus.2025;[Epub]     CrossRef
  • Comparison of Geniohyoid Muscle Morphology Assessment Using Conventional and Handheld Ultrasound Devices
    Tetsuo Ota, Mai Sano, Mitsugu Yoneda
    Cureus.2025;[Epub]     CrossRef
  • Multi-Center Validation of Artificial Intelligence-Based Video Analysis Platform for Automatic Evaluation of Swallowing Disorders
    Chang-Won Jeong, Dong-Wook Lim, Si-Hyeong Noh, Hee-Kyung Moon, Chul Park, Nayeon Ko, Min-Su Kim
    Diagnostics.2025; 16(1): 45.     CrossRef
  • Comparison of swallowing dynamics between jelly and thickened liquid commonly used for swallowing training in Japan
    Mineka Yoshikawa, Jun Kayashita, Masahiro Nakamori, Toshikazu Nagasaki, Shin Masuda, Mitsuyoshi Yoshida
    Scientific Reports.2025;[Epub]     CrossRef
  • Tongue pressure during swallowing is an independent risk factor for aspiration pneumonia in middle‐aged and older hospitalized patients: An observational study
    Yen‐Chin Chen, En‐Ni Ku, Che‐Wei Lin, Pei‐Fang Tsai, Jiun‐Ling Wang, Yu‐Fen Yen, Nai‐Ying Ko, Wen‐Chieh Ko, Nan‐Yao Lee
    Geriatrics & Gerontology International.2024; 24(S1): 351.     CrossRef
  • Swallowing dysfunction between the community-living older adults with and without comorbid conditions using Patient-Reported Outcome Measures (PROM)
    Himanshu Verma, Sourabh Kumar, Atul Sharma, Roshani Mishra, Banumathy Nagamani
    Geriatric Nursing.2024; 56: 64.     CrossRef
  • Contribution of Wireless Wi-Fi Intraoral Cameras to the Assessment of Swallowing Safety and Efficiency
    José Vergara, Anna Miles, Juliana Lopes de Moraes, Carlos Takahiro Chone
    Journal of Speech, Language, and Hearing Research.2024; 67(3): 821.     CrossRef
  • Oral and pharyngeal phases of swallowing in removable complete denture wearers
    Marina Rodrigues Montaldi, Cláudia Helena Lovato da Silva, Adriana Barbosa Ribeiro, Camila Borba de Araujo, Caroline Vieira Fortes, Roberto Oliveira Dantas
    RGO - Revista Gaúcha de Odontologia.2024;[Epub]     CrossRef
  • Short-term cortical activation changes associated with postural compensation in swallowing
    Kelsey L. Murray, Seng Mun Wong, Erin Kamarunas
    Experimental Brain Research.2024; 242(11): 2623.     CrossRef
  • Quantitative prediction of aspiration risk in head and neck cancer patients treated with radiation therapy
    Hannah C. Liu, Casey W. Williamson, Jingjing Zou, Jacob R. Todd, Tyler J. Nelson, Lindsay M. Hill, Kristen E. Linnemeyer, Gerald Henderson, Puja Madgula, Brian Faung, Assuntina G. Sacco, Lucas K. Vitzthum, Philip A. Weissbrod, Liza S. Blumenfeld, Loren K.
    Oral Oncology.2023; 136: 106247.     CrossRef
  • Correlation Between Articulatory Diadochokinetic Parameters and Dysphagia Parameters in Subacute Stroke Patients
    Back Min Oh, Hyun Seok, Sang-Hyun Kim, Seung Yeol Lee, Su Jung Park, Beom Jin Kim, Hyun Jung Kim
    Annals of Rehabilitation Medicine.2023; 47(3): 192.     CrossRef
  • Effects of Carbonated Thickened Drinks on Pharyngeal Swallowing with a Flexible Endoscopic Evaluation of Swallowing in Older Patients with Oropharyngeal Dysphagia
    Motoyoshi Morishita, Masahiko Okubo, Tatsuro Sekine
    Healthcare.2022; 10(9): 1769.     CrossRef
  • Aspiration pneumonia after cerebrovascular stroke: a comparison between patients with and without dysphagia
    N. A. Moulaei, N Ramroodi, S. M. N. A. Tabatabaie, H. A. Danesh, H. A. Khazaie
    Anesteziologie a intenzivní medicína.2022; 33(3-4): 148.     CrossRef
  • 13,688 View
  • 272 Download
  • 19 Web of Science
  • 23 Crossref

Pain & Musculoskeletal rehabilitation

Objective
To investigate differences in the relative sizes of the ankle-stabilizing muscles in individuals with versus without flexible flat feet and to determine predictors of symptom severity.
Methods
This cross-sectional study included 30 patients with symptomatic flexible flat feet and 24 normal controls. The following were evaluated: foot posture index, resting calcaneal stance position angle, radiographic findings (calcaneal pitch, Meary’s angle, talocalcaneal angle, talonavicular coverage angle [TNCA]), foot function index (FFI), and cross-sectional areas (CSA) of the tibialis anterior (TA), tibialis posterior (TP), and peroneus longus (PL) upon ultrasonographic examination. To address morphometric differences among participants, individual muscle measurements were normalized to proportions of total muscle CSA. Between-group differences were evaluated with independent t-tests. Correlations between muscle ratios, radiographic parameters, and FFI scores were investigated. Logistic regression analysis was performed to determine which parameters predicted severe symptoms.
Results
The relative size of the TP was significantly greater and those of the TA and PL were significantly smaller in patients with flat feet than in normal controls. Correlations were found among relative muscle CSA ratios, radiographic parameters, and FFI score. Linear regression analysis confirmed that the TNCA and the relative CSA of the PL were independent predictors of symptom severity.
Conclusion
This study found significant differences in the relative CSAs of the ankle muscles in patients with flexible flat feet versus individuals without flat feet; these differences were significantly correlated with anatomic abnormalities. Symptoms were more severe in patients with relatively greater forefoot abduction and relatively smaller PL.

Citations

Citations to this article as recorded by  
  • Plantar pressures in symptomatic and asymptomatic flexible flatfeet: how do they differ?
    Victoria Blackwood, Kelly A. Jeans, Rusty L. Hartman, Kirsten Tulchin-Francis, Jacob R. Zide, Anthony I. Riccio
    Journal of Pediatric Orthopaedics B.2026; 35(3): 250.     CrossRef
  • Does severity of the flatfoot deformity affect pain and mobility in adolescents with symptomatic flatfoot
    Matthew William, Daniel E. Pereira, Beltran Torres-Izquierdo, Claire Schaibley, Pooya Hosseinzadeh
    Journal of Pediatric Orthopaedics B.2025; 34(2): 189.     CrossRef
  • 정상발 및 평발 집단의 발목관절 토크 및 만성발목불안정증(CAI)의 특성 차이
    석경 안, 상근 조, 승재 김
    The Korean Journal of Physical Education.2024; 63(5): 339.     CrossRef
  • Relation of Flatfoot Severity with Flexibility and Isometric Strength of the Foot and Trunk Extensors in Children
    Min Hwan Kim, Sangha Cha, Jae Eun Choi, Minsoo Jeon, Ja Young Choi, Shin-Seung Yang
    Children.2022; 10(1): 19.     CrossRef
  • Effect of Foot Orthoses in Children With Symptomatic Flexible Flatfoot Based on Ultrasonography of the Ankle Invertor and Evertor Muscles
    Dong Joon Cho, So Young Ahn, Soo-Kyung Bok
    Annals of Rehabilitation Medicine.2021; 45(6): 459.     CrossRef
  • Biomechanical Evidence From Ultrasonography Supports Rigid Foot Orthoses in Children With Flatfoot
    Joon-Ho Shin
    Annals of Rehabilitation Medicine.2021; 45(6): 411.     CrossRef
  • 9,426 View
  • 191 Download
  • 7 Web of Science
  • 6 Crossref

Orthosis & Prosthesis

Comparison of the Effectiveness of Three Lumbosacral Orthoses on Early Spine Surgery Patients: A Prospective Cohort Study
Soo Woong Jang, Hee Seung Yang, Young Bae Kim, Joo Chul Yang, Kyu Bok Kang, Tae Wan Kim, Kwan Ho Park, Kyung Soo Jeon, Hee Dong Shin, Ye Eun Kim, Han Na Cho, Yun Kyung Lee, Young Lee, Seul Bin Na Lee, Dong Young Ahn, Woo Sob Sim, Min Jo, Gyu Jik Jo, Dong Bum Park, Gwan Su Park
Ann Rehabil Med 2021;45(1):24-32.   Published online February 9, 2021
DOI: https://doi.org/10.5535/arm.20158
Objective
To compare the convenience and effectiveness of the existing lumbosacral orthoses (LSO) (classic LSO and Cybertech) and a newly developed LSO (V-LSO) by analyzing postoperative data.
Methods
This prospective cohort study was performed from May 2019 to November 2019 and enrolled and analyzed 88 patients with degenerative lumbar spine disease scheduled for elective lumbar surgery. Three types of LSO that were provided according to the time of patient registration were applied for 6 weeks. Patients were randomized into the classic LSO group (n=31), Cybertech group (n=26), and V-LSO group (n=31). All patients were assessed using the Oswestry Disability Index (ODI) preoperatively and underwent plain lumbar radiography (anteroposterior and lateral views) 10 days postoperatively. Lumbar lordosis (LS angle) and frontal imbalance were measured with and without LSO. At the sixth postoperative week, a follow-up assessment with the ODI and orthosis questionnaire was conducted.
Results
No significant differences were found among the three groups in terms of the LS angle, frontal imbalance, ODI, and orthosis questionnaire results. When the change in the LS angle and frontal imbalance toward the reference value was defined as a positive change with and without LSO, the rate of positive change was significantly different in the V-LSO group (LS angle: 41.94% vs. 61.54% vs. 83.87%; p=0.003).
Conclusion
The newly developed LSO showed no difference regarding its effectiveness and compliance when compared with the existing LSO, but it was more effective in correcting lumbar lordosis.

Citations

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  • Bracing and Activity Restriction After Lumbar Discectomy Surgery: An International Survey of AO Spine Members
    Waeel O. Hamouda, Stipe Ćorluka, Sathish Muthu, Luca Ambrosio, Carla Cunha, Stjepan Ivandic, Mohamed A.R. Soliman, Fabrizio Russo, Sibylle Grad, In Ho Han, Gianluca Vadala, Hans-Jorg Meisel, Sam K. Cho, Tim S. Yoon, Jeffrey C. Wang, Amit Jain, Zorica Buse
    Neurospine.2026; 23(1): 109.     CrossRef
  • Spine Bracing: When to Utilize—A Narrative Review
    John L. Cerillo, Alexander N. Becsey, Chai P. Sanghadia, Kevin T. Root, Brandon Lucke-Wold
    Biomechanics.2023; 3(1): 136.     CrossRef
  • 11,407 View
  • 220 Download
  • 2 Web of Science
  • 2 Crossref
What is the Adequate Cuff Volume for Tracheostomy Tube? A Pilot Cadaver Study
Dong Min Kim, Myung Jun Shin, Sung Dong Kim, Yong Beom Shin, Ho Eun Park, Young Mo Kim, Jin A Yoon
Ann Rehabil Med 2020;44(5):402-408.   Published online September 28, 2020
DOI: https://doi.org/10.5535/arm.19210
Objective
To determine the patterns of tracheostomy cuff pressure changes with various air inflation amounts in different types of tracheostomy tubes to obtain basic data for appropriately managing longterm tracheostomy.
Methods
We performed tracheostomy on a 46-year-old male cadaver. Three types of tracheostomy tubes (single-cuffed, double-cuffed, and adjustable flange), divided into 8 different subtypes based on internal tube diameters and cuff diameters, were inserted into the cadaver. Air was inflated into the cuff, and starting with 1 mL air, the cuff pressure was subsequently measured using a manometer.
Results
For the 7.5 mm/14 mm tracheostomy tube, cuff inflation with 3 mL of air yielded a cuff pressure within the recommended range of 20–30 cmH2O. The 7.5 mm/24 mm tracheostomy tube showed adequate cuff pressure at 5 mL of air inflation. Similar values were observed for the 8.0 mm/16 mm and 8.0 mm/27 mm tubes. Double-cuffed tracheostomy cuff pressures (7.5 mm/20 mm and 8.0 mm/20 mm tubes) at 3 mL air inflation had cuff pressures of 18–20 cmH2O at both the proximal and distal sites. For the adjustable flange tracheostomy tube, cuff pressure at 6 mL of cuff air inflation was within the recommended range. Maximal cuff pressure was achieved at inflation with almost 14 mL of air, unlike other tube types.
Conclusion
Various types of tracheostomy tubes showed different cuff pressures after inflation. These values might aid in developing guidelines For patients who undergo tracheostomy and are discharged home without cuff pressure manometers, this standard might be helpful to develop guidelines.

Citations

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  • Tracheotomy
    Daniel Gorelik, Yixuan James Zheng, Franklin Wu, Ran A. Wang
    Medical Clinics of North America.2026; 110(1): 103.     CrossRef
  • Tracheostomy-associated bleeding: prevention, recognition, and management of a potentially fatal complication
    Cen-Hung Lin, Hang-Tsung Liu, Ching-Hua Hsieh
    Postgraduate Medical Journal.2026;[Epub]     CrossRef
  • Rethinking tracheostomy care: cuffless tubes for patients with aspiration
    Bettina Arca-Tschudi, Ludwig D. Schelosky, Paul Diesener, Svetlana Politz Geleva, Karsten Krakow
    Frontiers in Rehabilitation Sciences.2026;[Epub]     CrossRef
  • Fluid-Filled Tracheal Tube Cuffs: Implications for Speech, Sealing, and Safety
    Thomas C. Blakeman
    Respiratory Care.2025; 70(7): 930.     CrossRef
  • Impact of Low‐Volume, Low‐Pressure Tracheostomy Cuffs on Acute Mucosal Injury in Swine
    Alexandra J. Berges, Ioan A. Lina, Rafael Ospino, Hsiu‐Wen Tsai, Dacheng Ding, Jessica M. Izzi, Alexander T. Hillel
    Otolaryngology–Head and Neck Surgery.2022; 167(4): 716.     CrossRef
  • 13,507 View
  • 187 Download
  • 5 Web of Science
  • 5 Crossref
Changes in Pharyngeal Width Over Time as an Indicator of Dysphagia in Stroke Patients
Seungki Baek, Il Hwan Jung, Ho Young Lee, Jimin Song, Eunsil Cha, Kwang-Ik Jung, Woo-Kyoung Yoo, Suk Hoon Ohn
Ann Rehabil Med 2020;44(3):203-209.   Published online May 29, 2020
DOI: https://doi.org/10.5535/arm.19140
Objective
To verify the pharyngeal width at rest as a measurement that could be used to assess changes in the degree of dysphagia over time in stroke patients.
Methods
In a cohort of stroke patients, we performed serial measurements of the pharyngeal width at the midpoints of the second (C2) and third (C3) cervical vertebral bodies using lateral neck X-rays while the patients were at rest. The JOSCYL width, a parameter named after the first initial of each developers’ surname and defined as the average value of the upper and lower pharyngeal widths, was used to formulate the JOSCYL scale, which was calculated as the JOSCYL width × 100/neck circumference. All patients also underwent serial videofluoroscopic swallowing studies (VFSSs). The Spearman correlation analysis was used to detect correlations between the serial VFSS results, JOSCYL widths, and JOSCYL scale values.
Results
Over time, we observed significant positive and negative correlations of change in the JOSCYL width and scale with changes in the Penetration-Aspiration Scale and the Dysphagia Outcome and Severity Scale scores, respectively.
Conclusion
The JOSCYL width and JOSCYL scale clearly reflected changes in dysphagia in stroke patients over time. These parameters may provide an easier method for evaluating whether post-stroke dysphagia has been alleviated.

Citations

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  • Pharyngeal Structure and Dysphagia in Patients with Parkinson’s Disease and Related Disorders
    Eunjee Lee, Gyu Jin Kim, Hyewon Ryu, Kwang-Ik Jung, Woo-Kyoung Yoo, Suk Hoon Ohn
    Dysphagia.2024; 39(3): 468.     CrossRef
  • Prediction of Pharyngeal 3D Volume Using 2D Lateral Area Measurements During Swallowing
    Howell Henrian G. Bayona, Yoko Inamoto, Eichii Saitoh, Keiko Aihara, Masanao Kobayashi, Yohei Otaka
    Dysphagia.2024; 39(5): 783.     CrossRef
  • The influence of pharyngeal width on post-stroke laryngeal aspiration
    Wonil Kang, Jane Chung, Jeongeun Lee, Kwang-Ik Jung, Woo-Kyoung Yoo, Suk Hoon Ohn
    NeuroRehabilitation.2021; 49(3): 435.     CrossRef
  • 7,531 View
  • 131 Download
  • 3 Web of Science
  • 3 Crossref

Case Report

Precise Pulmonary Function Evaluation and Management of a Patient With Freeman-Sheldon Syndrome Associated With Recurrent Pneumonia and Chronic Respiratory Insufficiency
Jihyun Park, Seong-Woong Kang, Won Ah Choi, Yewon Lee, Han Eol Cho
Ann Rehabil Med 2020;44(2):165-170.   Published online April 29, 2020
DOI: https://doi.org/10.5535/arm.2020.44.2.165
Freeman-Sheldon syndrome (FSS) is a rare distal arthrogryposis syndrome. There are few reports on the respiratory insufficiency of FSS. Additionally, there is no detailed information on pulmonary functional evaluation. A 17-year-old male patient with FSS developed respiratory failure, leading him to be admitted to hospital several times for evaluation and treatment. Of those times he was admitted, two were due to pneumonia. His pulmonary functions were indicative of a restrictive lung disease potentially caused by severe scoliosis. After a non-invasive ventilatorwas applied correctly to the patient, pulmonary hypertension was normalized. His pulmonary function has been maintained for 13 years. Since receiving proper respiratory care, which includes assisted coughing methods, the patient has not developed pneumonia. It is important to properly evaluate the pulmonary function of patients who have FSS and scoliosis to eliminate the risk of long-term respiratory complications.

Citations

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  • Management of Respiratory Failure in ARSACS Using Non-Invasive Ventilation: A Case Report
    Hee Jae Park, Jihyun Kwon, Han Eol Cho
    Annals of CardioPulmonary Rehabilitation.2025; 5(1): 11.     CrossRef
  • Letter: Precise Pulmonary Function Evaluation and Management of a Patient With Freeman-Sheldon Syndrome Associated With Recurrent Pneumonia and Chronic Respiratory Insufficiency (Ann Rehabil Med 2020;44:165-70)
    Mikaela I. Poling, Craig R. Dufresne
    Annals of Rehabilitation Medicine.2020; 44(5): 409.     CrossRef
  • Response: Precise Pulmonary Function Evaluation and Management of a Patient With Freeman-Sheldon Syndrome Associated With Recurrent Pneumonia and Chronic Respiratory Insufficiency (Ann Rehabil Med 2020;44:165-70)
    Jihyun Park, Seong-Woong Kang, Won Ah Choi, Yewon Lee, Han Eol Cho
    Annals of Rehabilitation Medicine.2020; 44(5): 411.     CrossRef
  • 8,002 View
  • 166 Download
  • 2 Web of Science
  • 3 Crossref

Original Article

Differences of Spinal Curvature, Thoracic Mobility, and Respiratory Strength Between Chronic Neck Pain Patients and People Without Cervical Pain
Ji Hong Cheon, Na Na Lim, Geun Su Lee, Ki Hong Won, Sung Hoon Lee, Eun Young Kang, Hyun Kyung Lee, Younkyung Cho
Ann Rehabil Med 2020;44(1):58-68.   Published online February 29, 2020
DOI: https://doi.org/10.5535/arm.2020.44.1.58
Objective
To investigate the differences of spinal curvature, thoracic sagittal mobility, and respiratory strength between patients with chronic neck pain (CNP) and people without cervical pain, and to determine the correlation between respiratory strength and thoracic mobility in CNP patients.
Methods
A total of 78 participants were finally included in this study, of whom 30 had no cervical pain and 48 had CNP. The Neck Disability Index (NDI), cervical lordotic curvature, thoracic kyphotic curvature, thoracic sagittal range of motion (ROM), maximal inspiratory pressure (MIP), and maximal expiratory pressure (MEP) were measured and analyzed.
Results
In males, thoracic sagittal ROMMEP-MIP and MEP showed a significant difference between the no cervical pain group and the CNP group. In females, thoracic kyphotic curvature, thoracic sagittal ROMMEP-MIP, MIP, and MEP were significantly different between the no cervical pain group and the CNP group. Thoracic kyphotic curvature was significantly correlated with MEP and MIP in all population groups, and significantly correlated with NDI in the female group. Thoracic sagittal ROMMEP-MIP had a significant linear relationship with NDI, MEP, and MIP in all population groups.
Conclusion
The thoracic mobility during forced respiration was reduced in patients with CNP and was correlated with respiratory strength. Changes in the biomechanics of the cervicothoracic spine and rib cage due to CNP may contribute to impairment of respiratory strength.

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    Xiaojiao He, Sifeng Wen, Xuan Liu, Yutong Li, Shengbo Yang
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    Nurel Erturk, Fatma Kubra Cekok, Volkan Deniz
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    Sinem Ayyıldız Çınar, Birol Önal, Aynur Demirel, Halil Kamil Öge, Sevil Bilgin
    Ergoterapi ve Rehabilitasyon Dergisi.2026; 14(1): 79.     CrossRef
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    Marcel Leak, Hugo Giambini, Kelly Cheever, Sakiko Oyama
    Journal of Sport Rehabilitation.2026; 35(6): 497.     CrossRef
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    Merce Avellanet, Aurelia Mena, Esther Pages, Anna Boada-Pladellorens
    Cureus.2025;[Epub]     CrossRef
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    Francesco V. Ferraro, Ainoa Roldán, Mark A. Faghy
    Sport Sciences for Health.2025; 21(3): 2283.     CrossRef
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    BMC Musculoskeletal Disorders.2025;[Epub]     CrossRef
  • Association Between Chronic Neck Pain and Increased Risk of Chronic Respiratory Diseases in Middle-Aged and Elderly Chinese Adults: A Cohort Study Based on CHARLS
    Mingyang Yi, Zhen Zhang, Haixia Li, Junting Sai, Weike Li, Zhiwan Wang
    Journal of Pain Research.2025; Volume 18: 7275.     CrossRef
  • Differences of diaphragmatic muscle contraction between female patients with chronic neck pain and asymptomatic controls: A case-control study based on ultrasonography
    Gamze Yalcinkaya Colak, Seher Ozyurek, Yesim Salik Sengul, Orhan Kalemci
    Musculoskeletal Science and Practice.2024; 69: 102894.     CrossRef
  • Effect of Chronic Non-specific Neck Pain on Aerobic Capacity in Females
    Özlem MENEVŞE, Filiz ALTUĞ, Orçin TELLİ ATALAY
    Bezmialem Science.2024; 12(1): 55.     CrossRef
  • Respiratory dysfunction in patients with chronic neck pain: systematic review and meta-analysis
    Ibai López-de-Uralde-Villanueva, Tamara del Corral, Rodrigo Salvador-Sánchez, Santiago Angulo-Díaz-Parreño, José-Javier López-Marcos, Gustavo Plaza-Manzano
    Disability and Rehabilitation.2023; 45(15): 2422.     CrossRef
  • Respiratory Function Analysis in Patients with Chronic Pain: An Umbrella Review and Meta-Analysis of Pooled Findings
    Ferran Cuenca-Martínez, Núria Sempere-Rubio, Elena Muñoz-Gómez, Sara Mollà-Casanova, Enrique Carrasco-González, Francisco M. Martínez-Arnau
    Healthcare.2023; 11(9): 1358.     CrossRef
  • Impact of Indoor Air Quality and Breathing on Back and Neck Pain: A Systematic Review
    Ezequiel D Gherscovici, John M Mayer
    Cureus.2023;[Epub]     CrossRef
  • Association between Smartphone Addiction and Breathing Pattern in Sedentary Young College-Going Students – A Cross-Sectional Study
    IK Shah, A Kumar, S Rajasekar, AA Pathak, N Suvarna, K Gopal, R Muthukrishnan
    Nigerian Journal of Clinical Practice.2023; 26(11): 1637.     CrossRef
  • Chronic neck pain and respiratory dysfunction: a review paper
    Shruti P. Nair, Chaitrali S. Panchabhai, Vrushali Panhale
    Bulletin of Faculty of Physical Therapy.2022;[Epub]     CrossRef
  • Effects of breathing re-education on endurance, strength of deep neck flexors and pulmonary function in patients with chronic neck pain: A randomised controlled trial
    Sahreen Anwar, Syed A. Arsalan, Hamayun Zafar, Ashfaq Ahmed, Syed A. Gillani, Asif Hanif
    South African Journal of Physiotherapy.2022;[Epub]     CrossRef
  • Pulmonary Functions in Patients With Chronic Neck Pain: A Case-Control Study
    Figen Dağ, Serkan Taş, Özlem Bölgen Çimen
    Journal of Manipulative and Physiological Therapeutics.2022; 45(4): 290.     CrossRef
  • A Comparative Study of a Novel Postural Garment Versus Exercise for Women with Nonspecific Cervical Pain
    Merce Avellanet, Anna Boada-Pladellorens, Esther Pages, Aleix Dorca, Betlem Sabria, Michael Pfeifer, Elvira Gea
    Spine.2021; 46(22): 1517.     CrossRef
  • Neck Stabilization Exercises Enhance Respiratory Function after Stroke: Respiratory Function Index Change Trajectory Analyzed Using a Hierarchical Linear Model
    So-Hyun Kim, Sung-Hyoun Cho
    Medicina.2021; 57(12): 1312.     CrossRef
  • 14,305 View
  • 225 Download
  • 19 Web of Science
  • 19 Crossref

Case Reports

Subacute Combined Degeneration Caused by Nitrous Oxide Intoxication: A Report of Two Cases
Cheol Choi, Taehee Kim, Ki Deok Park, Oh Kyung Lim, Ju Kang Lee
Ann Rehabil Med 2019;43(4):530-534.   Published online August 31, 2019
DOI: https://doi.org/10.5535/arm.2019.43.4.530
We report two cases of subacute combined degeneration (SCD) caused by nitrous oxide (N2O) gas intoxication, which is rarely reported in Korea. Two patients recreationally inhaled N2O gas daily for several months. They presented with paresthesia of limbs, voiding difficulty, and gait disturbance. The initial vitamin B12 levels were normal or decreased, but homocysteine levels of the two patients were increased. Magnetic resonance imaging of the cervical spine showed T2-weighted hyperintensity in the bilateral dorsal columns of the cervical spinal cord. Electromyography and somatosensory evoked potential tests for both patients suggested posterior column lesion of the spinal cord combined with sensorimotor polyneuropathy. According to these findings, we concluded that the two patients had SCD. The patient’s symptoms partially improved after cessation of N2O gas inhalation and the receiving of vitamin B12 supplementation therapy. As the incidence of recreational N2O gas inhalation is increasing in Korea, physicians must be alert to the N2O induced SCD in patients presenting with progressive myelopathy.

Citations

Citations to this article as recorded by  
  • Trends in nitrous oxide abuse and misuse: a 22-year analysis of United States poison center data
    Courtney Temple, Amber Lin, Adrienne Hughes
    Clinical Toxicology.2026; 64(4): 282.     CrossRef
  • The Toxic Legacy of Recreational Nitrous Oxide Use: A Systematic Review and Meta-Analysis of Multisystem Complications From Functional Vitamin B12 Deficiency
    Richa Tikaria, Adam Kapp, Samantha Shook, Ling Wang
    Cureus.2026;[Epub]     CrossRef
  • Neurotoxicity mechanisms and clinical implications of six common recreational drugs
    Jing Wang, Yulei Hao, Di Ma, Liangshu Feng, Feng Yang, Pingxu An, Xingqi Su, Jiachun Feng
    Frontiers in Pharmacology.2025;[Epub]     CrossRef
  • Current regulations in context: Scraping Australia's online nitrous oxide market
    Samuel Gresham, Jacques Eugene Raubenheimer
    International Journal of Drug Policy.2025; 139: 104773.     CrossRef
  • Nitrous oxide use and psychiatric disorders: a retrospective clinical cohort study on prevalence and patterns
    Rebecca Paetow, Maike Franziska Dohrn, Michelle Finner-Prével, Leona Boesehans, Dariush Henning, Marcus Rust, Thomas Frodl
    Frontiers in Psychiatry.2025;[Epub]     CrossRef
  • Neurological Manifestations Induced by Nitrous Oxide Abuse
    Maud Pichon, Loubna Majhadi, Anne-Marie Menn
    The Neurologist.2024; 29(2): 113.     CrossRef
  • It is time to take nitrous oxide seriously without waiting for more evidence of harms
    Julaine Allan, Jacqui Cameron, Helen Simpson, Kenny Kor
    Addiction.2024; 119(4): 619.     CrossRef
  • Nitrous oxide tank cold burn to the forearm: a case study and discussion of the literature
    Oliver Allen, Muireann Keating
    Emergency Nurse.2024; 32(4): 22.     CrossRef
  • Mechanisms and recent advances in the diagnosis and treatment of nitrous oxide-induced peripheral neuropathy: a narrative review
    Xiaodi Zou, Fangyu Yi, Weijie Zhou, Yanzhao Dong, Ahmad Alhaskawi, Haiying Zhou, Sohaib Hasan Abdullah Ezzi, Vishnu Goutham Kota, Mohamed Hasan Abdulla Hasan Abdulla, Olga Alenikova, Sahar Ahmed Abdalbary, Hui Lu, Changxin Wang
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  • Clinical case of funicular myelosis in combination with a concomitant genetic predisposition to folate cycle disorder
    O.D. Shulga , E.A. Popko, A.S. Chabanova , O.G. Kotsiuba , Q. Hussain
    Medicni perspektivi.2024; 29(2): 229.     CrossRef
  • Nitrous Oxide-Induced Vitamin B12 Deficiency and Myelopathy in Whippets Abusers: A Report of Two Cases
    Fahim Barmak, Jamil Numan, Mariam Shabih, Justin Nolte, Jason Adams, Paul Ferguson, Syed Hashim A Inam
    Cureus.2024;[Epub]     CrossRef
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    Charlotte Buttery, Jonathan Birns, Jamie Gibson, Gareth David Jones
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  • Severe length‐dependent peripheral polyneuropathy in a patient with subacute combined spinal cord degeneration secondary to recreational nitrous oxide abuse: A case report and literature review
    Ventzislav Bonev, Mark Wyatt, Matthew J. Barton, Michael A. Leitch
    Clinical Case Reports.2023;[Epub]     CrossRef
  • Subacute Combined Degeneration of the Spinal Cord Secondary to Nitrous Oxide Abuse
    Aamir Khan, Ayesha Zafar, Hira Hamid, Bilal Ahmad
    Cureus.2023;[Epub]     CrossRef
  • A Case of Subacute Degeneration of the Spinal Cord Due to Vitamin B12 Deficiency Triggered by Nitrous Oxide Use
    Alvin Soh Weng Yan, Abuobeida Ali , Jordon Kong, Lewis Cooney, Junaid Akhtar, Tina Maheswaran, Michael Davies, Yash Prasad
    Cureus.2023;[Epub]     CrossRef
  • Update on Toxic Neuropathies
    Jannik Peters, Nathan P. Staff
    Current Treatment Options in Neurology.2022; 24(5): 203.     CrossRef
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    Radhika Sood, Thibault Parent
    Medicine.2022; 101(31): e28611.     CrossRef
  • Severe Isolated Peripheral Polyneuropathy without Myelopathy after Nitrous Oxide Abuse: A Case Report
    Seung-Min Baek, Seungbok Lee, Yu-Mi Kim, Eun-Sil Kim
    Journal of Electrodiagnosis and Neuromuscular Diseases.2022; 24(2): 50.     CrossRef
  • A Systematic Review of Recreational Nitrous Oxide Use: Implications for Policy, Service Delivery and Individuals
    Julaine Allan, Jacqui Cameron, Juliana Bruno
    International Journal of Environmental Research and Public Health.2022; 19(18): 11567.     CrossRef
  • Vitamin B12status in health and disease: a critical review. Diagnosis of deficiency and insufficiency – clinical and laboratory pitfalls
    Agata Sobczyńska-Malefora, Edgard Delvin, Andrew McCaddon, Kourosh R. Ahmadi, Dominic J. Harrington
    Critical Reviews in Clinical Laboratory Sciences.2021; 58(6): 399.     CrossRef
  • Nitrous Oxide Abuse‐Induced Subacute Combined Degeneration: Classic Neuroimaging Findings on MRI
    A.K. Kirsch, S.M. Allison, S.A. Kilanowski
    Neurographics.2021; 11(2): 72.     CrossRef
  • Spectrum of nitrous oxide intoxication related neurological disorders in Korea: a case series and literature review
    Jungsoo Lee, Yangmi Park, Hyunkee Kim, Nakhoon Kim, Wonjae Sung, Sanggon Lee, Jinseok Park
    Annals of Clinical Neurophysiology.2021; 23(1): 108.     CrossRef
  • Nitrous oxide‐related neurological disorders: Clinical, laboratory, neuroimaging, and electrophysiological findings
    Jiwei Jiang, Xiuli Shang, Xiaoting Wang, Hanze Chen, Wenyi Li, Yanli Wang, Jun Xu
    Brain and Behavior.2021;[Epub]     CrossRef
  • Serum copper decrease and cerebellar atrophy in patients with nitrous oxide-induced subacute combined degeneration: two cases report
    Jie Cao, Lusen Ran, Chenchen Liu, Zhijun Li
    BMC Neurology.2021;[Epub]     CrossRef
  • Polyneuropathy Following Nitrous Oxide Abuse
    Jin Young Seo, Yerim Kim, Ji won Lee, Jong Seok Bae
    Korean Journal of Neuromuscular Disorders.2021; 13(2): 33.     CrossRef
  • Subacute Combined Degeneration from Nitrous Oxide Abuse
    Monique A. Mogensen, James R. Fink
    PM&R.2020; 12(4): 428.     CrossRef
  • Clinical, Electrophysiological and Radiological Features of Nitrous Oxide-Induced Neurological Disorders


    Lei Bao, Qing Li, Qingjie Li, Hao Chen, Ruixue Zhang, Hongjuan Shi, Guiyun Cui
    Neuropsychiatric Disease and Treatment.2020; Volume 16: 977.     CrossRef
  • Happy Balloon Induced Myeloneuropathy
    Soo-Hyun Park, Ho-Sang Yoon, Paul Kim, Nam-Hee Kim
    Journal of the Korean Neurological Association.2020; 38(4): 327.     CrossRef
  • 11,819 View
  • 422 Download
  • 20 Web of Science
  • 28 Crossref
Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report
Minji Chae, Seungbeen Hong, Na Young Jung, Won Seok Chang, Sung-Rae Cho
Ann Rehabil Med 2019;43(3):335-340.   Published online June 28, 2019
DOI: https://doi.org/10.5535/arm.2019.43.3.335
Deep brain stimulation (DBS) in internal globus pallidus is considered to be a good option for controlling generalized dystonia in patients with this condition. In this relation, it is known that DBS has already been shown to have significant effects on primary dystonia, but is seen as controversial in secondary dystonia including cerebral palsy (CP). On the other hand, intrathecal baclofen (ITB) has been known to reduce spasticity and dystonia in patients who did not respond to oral medications or botulinum toxin treatment. Here, we report a patient with dystonic CP, who received the ITB pump implantation long after the DBS and who noted remarkable improvement in the 36-Item Short Form Health Survey, Dystonia Rating Scale, Modified Barthel Index, and visual analog scale scores for pain after an ITB pump implantation was used as compared with DBS. To our knowledge, the present case report is the first to demonstrate the effects of an ITB pump on reducing pain and dystonia and improving quality of life and satisfaction, compared with DBS in a patient with CP.

Citations

Citations to this article as recorded by  
  • Stepwise surgical management of spasticity and dystonia in severe pediatric cerebral palsy: a case report involving selective dorsal rhizotomy, intrathecal baclofen therapy, and deep brain stimulation
    Jong Won Byun, Jae Meen Lee, Yong Beom Shin, Jin A. Yoon, Soo-Yeon Kim
    Child's Nervous System.2026;[Epub]     CrossRef
  • Intrathecal baclofen, selective dorsal rhizotomy, and extracorporeal shockwave therapy for the treatment of spasticity in cerebral palsy: a systematic review
    Amogh Kudva, Mickey E. Abraham, Justin Gold, Neal A. Patel, Julian L. Gendreau, Yehuda Herschman, Antonios Mammis
    Neurosurgical Review.2021; 44(6): 3209.     CrossRef
  • 10,522 View
  • 164 Download
  • 2 Web of Science
  • 2 Crossref

Review Article

Emerging Issues in Cerebral Palsy Associated With Aging: A Physiatrist Perspective
You Gyoung Yi, Se Hee Jung, Moon Suk Bang
Ann Rehabil Med 2019;43(3):241-249.   Published online June 28, 2019
DOI: https://doi.org/10.5535/arm.2019.43.3.241
The population of adults diagnosed with cerebral palsy (CP) is increasing along with the survival rate of children born with the disability. Adults with CP need health services for the continued monitoring and management of their condition. Moreover, the development of additional health problems in adulthood increases the need for ongoing access to health services. Adults with CP manifest a higher rate of chronic health conditions and eventual decline in strength and functional reserve, deterioration in physical activity, increased risk of musculoskeletal complications, and gradual changes in swallowing ability. They are also reported to exhibit difficulty engaging socially and have a low health-related quality of life (QOL). However, there are a large number of adults with CP who cannot access medical services adequately and are therefore not effectively treated. To overcome these apparent challenges, we need to fully comprehend the healthcare needs of adults with CP to develop adultfocused health services. Further research is needed regarding the impact of physical activity, nutrition, sarcopenia, myeloradiculopathy, and swallowing function on QOL.

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Original Articles

Effects of Copy Number Variations on Developmental Aspects of Children With Delayed Development
Kee-Boem Park, Kyung Eun Nam, Ah-Ra Cho, Woori Jang, Myungshin Kim, Joo Hyun Park
Ann Rehabil Med 2019;43(2):215-223.   Published online April 30, 2019
DOI: https://doi.org/10.5535/arm.2019.43.2.215
Objective
To determine effects of copy number variations (CNV) on developmental aspects of children suspected of having delayed development.
Methods
A retrospective chart review was done for 65 children who underwent array-comparative genomic hybridization after visiting physical medicine & rehabilitation department of outpatient clinic with delayed development as chief complaints. Children were evaluated with Denver Developmental Screening Test II (DDST-II), Sequenced Language Scale for Infants (SELSI), or Preschool Receptive-Expressive Language Scale (PRES). A Mann-Whitney U test was conducted to determine statistical differences of developmental quotient (DQ), receptive language quotient (RLQ), and expressive language quotient (ELQ) between children with CNV (CNV(+) group, n=16) and children without CNV (CNV(–) group, n=37).
Results
Of these subjects, the average age was 35.1 months (mean age, 35.1±24.2 months). Sixteen (30.2%) patients had copy number variations. In the CNV(+) group, 14 children underwent DDST-II. In the CNV(–) group, 29 children underwent DDSTII. Among variables, gross motor scale was significantly (p=0.038) lower in the CNV(+) group compared with the CNV(–) group. In the CNV(+) group, 5 children underwent either SELSI or PRES. In the CNV(–) group, 27 children underwent above language assessment examination. Both RLQ and ELQ were similar between the two groups.
Conclusion
The gross motor domain in DQ was significantly lower in children with CNV compared to that in children without CNV. This result suggests that additional genetic factors contribute to this variability. Active detection of genomic imbalance could play a vital role when prominent gross motor delay is presented in children with delayed development.

Citations

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  • Complex de novo tetrasomy and trisomy of 2p22.2 involving EIF2AK2 in a child with global developmental delay: a case report and literature review
    Jun Wang, Xin Duan, Chaolong Xu, Tianyu Song, Danmin Shen, Fang Fang
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    Catherine A. Brownstein, Elise Douard, Robin L. Haynes, Hyun Yong Koh, Alireza Haghighi, Christine Keywan, Bree Martin, Sanda Alexandrescu, Elisabeth A. Haas, Sara O. Vargas, Monica H. Wojcik, Sébastien Jacquemont, Annapurna H. Poduri, Richard D. Goldstei
    Advanced Genetics.2023;[Epub]     CrossRef
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    Nadja Louw, Nadia Carstens, Zané Lombard
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    Genetics in Medicine.2021; 23(4): 669.     CrossRef
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    Ondrej Pös, Jan Radvanszky, Jakub Styk, Zuzana Pös, Gergely Buglyó, Michal Kajsik, Jaroslav Budis, Bálint Nagy, Tomas Szemes
    Applied Sciences.2021; 11(2): 819.     CrossRef
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Predictive Value of Pharyngeal Width at Rest (JOSCYL Width) for Aspiration in Elderly People
Ho Young Lee, Il Hwan Jung, Eunsil Cha, Jimin Song, Kwang-Ik Jung, Woo-Kyoung Yoo, Suk Hoon Ohn
Ann Rehabil Med 2019;43(2):187-194.   Published online April 30, 2019
DOI: https://doi.org/10.5535/arm.2019.43.2.187
Objective
To develop a new tool for aspiration risk prediction based on pharyngeal width at rest in older adults with symptoms of aspiration.
Methods
Lateral cervical spine roentgenograms were obtained from 33 older adult patients who complained of dysphagia and from 33 healthy, age-matched controls. Pharyngeal width at rest was measured at two points. We named the average of these two pharyngeal widths ‘JOSCYL Width’, calculated ‘JOSCYL Scale’, and compared these parameters between dysphagia and control groups. Correlations of individual JOSCYL Width and JOSCYL Scale, with Penetration Aspiration Scale (PAS) and Dysphagia Outcome and Severity Scale (DOSS) scores were analyzed for the dysphagia group. To determine optimal cutoff points for predicting aspiration, a receiver operating characteristic curve analysis was performed on JOSCYL Width and JOSCYL Scale.
Results
Both JOSCYL Width and JOSCYL Scale of the dysphagia group were larger than those of the control group (p<0.001). The correlation between JOSCYL Width and severity of dysphagia was significant for the dysphagia group (PAS p=0.007; DOSS p=0.012). The correlation between JOSCYL Scale and the severity of dysphagia was also significant for the dysphagia group (PAS p=0.009; DOSS p=0.011). Optimal cutoffs for JOSCYL Width and JOSCYL Scale for predicting aspiration were 20.0 mm and 5.9, respectively.
Conclusion
JOSCYL Width and JOSCYL Scale can be new indicators for predicting aspiration in older adults. They are both precise and easy to use.

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  • Pharyngeal Structure and Dysphagia in Patients with Parkinson’s Disease and Related Disorders
    Eunjee Lee, Gyu Jin Kim, Hyewon Ryu, Kwang-Ik Jung, Woo-Kyoung Yoo, Suk Hoon Ohn
    Dysphagia.2024; 39(3): 468.     CrossRef
  • Prediction of Pharyngeal 3D Volume Using 2D Lateral Area Measurements During Swallowing
    Howell Henrian G. Bayona, Yoko Inamoto, Eichii Saitoh, Keiko Aihara, Masanao Kobayashi, Yohei Otaka
    Dysphagia.2024; 39(5): 783.     CrossRef
  • The influence of pharyngeal width on post-stroke laryngeal aspiration
    Wonil Kang, Jane Chung, Jeongeun Lee, Kwang-Ik Jung, Woo-Kyoung Yoo, Suk Hoon Ohn
    NeuroRehabilitation.2021; 49(3): 435.     CrossRef
  • Changes in Pharyngeal Width Over Time as an Indicator of Dysphagia in Stroke Patients
    Seungki Baek, Il Hwan Jung, Ho Young Lee, Jimin Song, Eunsil Cha, Kwang-Ik Jung, Woo-Kyoung Yoo, Suk Hoon Ohn
    Annals of Rehabilitation Medicine.2020; 44(3): 203.     CrossRef
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  • 4 Web of Science
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Correlation of Swallowing Function With Bilateral Diaphragmatic Movement in Hemiplegic Stroke Patients
Ra Yu Yun, Ho Eun Park, Ji Won Hong, Yong Beom Shin, Jin A Yoon
Ann Rehabil Med 2019;43(2):156-162.   Published online April 30, 2019
DOI: https://doi.org/10.5535/arm.2019.43.2.156
Objective
To investigate difference in bilateral diaphragm movement of patients with tracheal aspiration according to post stroke residue severity and determine correlations of Penetration-Aspiration Scale (PAS), residue scale, and bilateral diaphragm movement.
Methods
A total of 47 patients diagnosed with hemiplegic stroke were enrolled in this study. PAS, severity of valleculae, and pyriform sinus retention during videofluoroscopic swallowing study (VFSS) were assessed. Bilateral fluoroscopic diaphragm movements during spontaneous breathing and forced breathing were measured.
Results
Patients with tracheal aspiration (PAS≥6) had significantly (p=0.035) lower ipsilateral diaphragm movement during spontaneous breathing. Post-swallow residue severity showed statistically significant (p=0.028) difference in patients with ipsilateral diaphragm movement during forced breathing. In linear regression analysis, PAS showed weak correlations with ipsilateral spontaneous diaphragm movement (r=0.397, p=0.006), ipsilateral forced diaphragm movement (r=0.384, p=0.008), and contralateral forced diaphragm movement (r=0.323, p=0.027). Weak correlation was also observed between post swallow residue severity and ipsilateral diaphragm movement during spontaneous breathing (r=0.331, p=0.023) and forced breathing (r=0.343, p=0.018).
Conclusion
We confirmed the relationship between swallowing function and bilateral diaphragm movement in this study. The severity of dysphagia after hemiplegic stroke was correlated with bilateral diaphragm movement. Further longitudinal studies are needed to assess the effect of breathing exercise on post-stroke dysphagia.

Citations

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  • Correlation between swallowing and diaphragmatic functions in stroke patients with hemiplegia: a cross-sectional observational study
    Xiaoman Liu, Jingrong Zhao, Yanyu Wu, Ying Yang, Xiang Zhu, Yu Wang, Chen Zhang, Mengxue Liu, Yanyu Song, Jie Jia
    Scientific Reports.2026;[Epub]     CrossRef
  • Inspiratory Muscle Training for Patients With Chronic Obstructive Pulmonary Disease: A Narrative Review
    Bruno Bordoni, Bruno Morabito, Allan R Escher
    Cureus.2026;[Epub]     CrossRef
  • The Impact of Ageing on Diaphragm Function and Maximal Inspiratory Pressure: A Cross-Sectional Ultrasound Study
    Toru Yamada, Taro Minami, Takahiro Shinohara, Shuji Ouchi, Suguru Mabuchi, Shunpei Yoshino, Ken Emoto, Kazuharu Nakagawa, Kanako Yoshimi, Mitsuko Saito, Ayane Horike, Kenji Toyoshima, Yoshiaki Tamura, Atsushi Araki, Ryoichi Hanazawa, Akihiro Hirakawa, Tak
    Diagnostics.2025; 15(2): 163.     CrossRef
  • Methods for Diagnosing and Predicting Diaphragm Dysfunction in the Recovery Period of a Stroke: a Narrative Review
    Ekaterina A. Melnikova, Elena Yu. Starkova, Nadezhda N. Vladimirova, Evgeniya M. Tsvetkova, Vladislav Yu. Litau
    Bulletin of Rehabilitation Medicine.2023; 22(4): 138.     CrossRef
  • Assessment of Diaphragm in Hemiplegic Patients after Stroke with Ultrasound and Its Correlation of Extremity Motor and Balance Function
    Xiaoman Liu, Qingming Qu, Panmo Deng, Yuehua Zhao, Chenghong Liu, Conghui Fu, Jie Jia
    Brain Sciences.2022; 12(7): 882.     CrossRef
  • Respiratory‐swallow coordination in a rat model of chemoradiation
    Linda M. Rowe, Nadine P. Connor, John A. Russell
    Head & Neck.2021; 43(10): 2954.     CrossRef
  • Neck Stabilization Exercises Enhance Respiratory Function after Stroke: Respiratory Function Index Change Trajectory Analyzed Using a Hierarchical Linear Model
    So-Hyun Kim, Sung-Hyoun Cho
    Medicina.2021; 57(12): 1312.     CrossRef
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    Sung-Hyoun Cho, Ki-Bok Choi
    Healthcare.2020; 8(3): 222.     CrossRef
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  • 6 Web of Science
  • 8 Crossref
Comparison of Dysphagia Between Infratentorial and Supratentorial Stroke Patients
Yong Kyun Kim, Jung Hyun Cha, Kyun Yeon Lee
Ann Rehabil Med 2019;43(2):149-155.   Published online April 30, 2019
DOI: https://doi.org/10.5535/arm.2019.43.2.149
Objective
To compare dysphagia between infratentorial stroke patients and supratentorial stroke patients.
Methods
Subjects of this study were patients with post-stroke dysphagia (PSD) who were admitted to our medical institution between May 2014 and June 2017. We evaluated a total of 64 patients with PSD. A videofluoroscopic swallowing study (VFSS) was performed to determine dysphagia severity. We measured the following parameters: pharyngeal transit time (PTT), post-swallow pharyngeal remnant, Penetration Aspiration Scale (PAS) scores, and Functional Dysphagia Scale (FDS). We analyzed patient’s results from VFSS performed at admission. All VFSS images were recorded using a camcorder running at 30 frames per second. An AutoCAD 2D screen was used to measure post-swallow pharyngeal remnant.
Results
In this study, PTT and FDS were similar (p>0.05) between infratentorial stroke patients and supratentorial stroke patients. However, there were significant differences in pharyngeal remnant and PAS scores between the two groups (p<0.01 and p<0.05, respectively).
Conclusion
Both pharyngeal remnant and PAS score registered higher levels from VFSS test for infratentorial stroke patients than those for supratentorial stroke patients. This suggests greater chances of problems occurring with swallowing, the major functions of pons. Thus, clinicians should pay particular attention to active dysphagia evaluation and treatment in PSD of infratentorial stroke patients.

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  • The Effects of Deep Transcranial Magnetic Stimulation Targeting the Insular Cortex in Patients with Infratentorial Stroke and Aspiration: A Randomized Controlled Trial
    Jia Qiao, Meng Dai, Lian Wang, Xiangxiang Zhang, Fang Sun, Zhimin Wu, Xin Li, Liujie Su, Yadan Zheng, Wenhao Huang, Hongmei Wen, Zulin Dou
    Archives of Physical Medicine and Rehabilitation.2026; 107(7): 1690.     CrossRef
  • Cortical morphological changes in stroke-associated dysarthria patients
    Jin Zhou, Shilong Zhao, Wenjing Zhang, Tianyuan Wei, Hongxia Zhang, Weijin Liu, Chunlin Li, Xiaoxia Du
    Frontiers in Neurology.2026;[Epub]     CrossRef
  • Multidisciplinary and stratified non-pharmacological airway clearance intervention to prevent stroke-associated pneumonia: a quasi-experimental study
    Yingchun Chen, Lihong Huang, Xi Huang, In Hye Park, Chao Wu, Yueli Gong, Jie Du, Jiawen You, Yang Liu
    European Clinical Respiratory Journal.2026;[Epub]     CrossRef
  • Establishment and evaluation of a predictive scoring system for successful decannulation of tracheostomy in neurosurgery patients
    Yin Hu, Lifang Mao, Qing Liu, Yanhua Jiang, Shun Li
    Frontiers in Neurology.2026;[Epub]     CrossRef
  • Voices of Stroke Survivors With Dysphagia: A Roy Adaptation Model‐Based Qualitative Analysis
    Abdullah Avcı, Fadime Cennet Çokgün
    Brain and Behavior.2026;[Epub]     CrossRef
  • The Respiratory-Swallow Coordination may be Related to Aspiration in Infratentorial Stroke Patients
    Jia Qiao, Meng Dai, Fang Sun, Zhi-Min Wu, Lian Wang, Qiu-Pin Ye, Yong Dai, Hong-Mei Wen, Zu-Lin Dou
    Dysphagia.2025; 40(4): 952.     CrossRef
  • Investigation of neurogenic dysphagia in commonly seen neurological diseases
    Müberra Tanrıverdi, Senanur Düzenli, Merve Sevinç Gündüz, Ayça Arslantürk, Ayşenur Erekdağ
    Anadolu Kliniği Tıp Bilimleri Dergisi.2025; 30(1): 150.     CrossRef
  • Post-stroke dysphagia: identifying the evidence missing
    Zicong Wang, Ran Shi, Paulo Moreira
    Frontiers in Medicine.2025;[Epub]     CrossRef
  • Temporal Characteristics of Penetration and Aspiration in Patients with Severe Dysphagia Associated with Lateral Medullary Syndrome
    Meng Dai, Jiao Qiao, Huayu Chen, Zhonghui Shi, Binbin Liu, Zu-Lin Dou
    Dysphagia.2024; 39(2): 255.     CrossRef
  • Correlation between lesion location and dysphagia characteristics in post-stroke patients
    Qing-lu Yang, Yang Chen, Xue-jie Wang, Hui-ying Qiu, Meng-ting Chen, Xu-hui Zhou, Chu-yao Jian, Shao-feng Zhao
    Journal of Stroke and Cerebrovascular Diseases.2024; 33(6): 107682.     CrossRef
  • Factors Influencing Early Diagnosis and Poor Prognosis of Dysphagia After Senile Ischemic Stroke
    Qingxian Fan, Yan Zhao, Jianrong Zhang, Yu’e Wu, Qingping Huang, Ying Gao, Jingqin Wang, Changqiong Guo, Shuqing Zhang
    Journal of Molecular Neuroscience.2024;[Epub]     CrossRef
  • Effects of Cerebellar Repetitive Transcranial Magnetic Stimulation in the Treatment of Post-Stroke Dysphagia: A Meta-Analysis and Systematic Review of Randomized Controlled Trials
    Ying Liu, Shao Yin, Xinwei Yang, Shanshan Luo, Fengya Zhu, Zijian Zeng, Qian Hu, Li Xu, Qian Yu
    European Neurology.2024; 87(2): 67.     CrossRef
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    Pan Zhang, Pengfei Xu, Zuowei Duan, Feng Zhang, Yirong Fang, Dingyi Yan, Hanhong Zhang, Qiankun Cai, Xianjun Huang, Zhixin Huang, Mengmeng Gu, Lulu Xiao, Jinjing Wang, Wen Sun
    Journal of NeuroInterventional Surgery.2023; 15(e2): e270.     CrossRef
  • Quantitative Analysis of Temporal Parameters Correlated with Aspiration and Lesion Location in Stroke Patients
    Jeong Min Kim, Ji Eun Park, Seung Jun Baek, Seung Nam Yang
    Dysphagia.2023; 38(6): 1487.     CrossRef
  • Effect of cerebellar transcranial magnetic stimulation with double-cone coil on dysphagia after subacute infratentorial stroke: A randomized, single-blinded, controlled trial
    Meng Dai, Jia Qiao, Zhonghui Shi, Xiaomei Wei, Huayu Chen, Luxi Shen, Hongmei Wen, Zulin Dou
    Brain Stimulation.2023; 16(4): 1012.     CrossRef
  • Postoperative Dysphagia Aortica: Comparison with Other Dysphagia
    Jong Keun Kim, Sangpil Son, InHyuk Suh, Jin Seok Bae, Jong Youb Lim
    Dysphagia.2022; 37(5): 1112.     CrossRef
  • Predictive value of the videofluoroscopic swallowing study for long-term mortality in patients with subacute stroke
    Daham Kim, Jae-Hyung Kim, Si-Woon Park, Hyung-Wook Han, Sang Joon An, Yeong In Kim, Hyo Jin Ju, YoonHee Choi, Doo Young Kim
    Medicine.2022; 101(4): e28623.     CrossRef
  • Increased cortical-medulla functional connectivity is correlated with swallowing in dysphagia patients with subacute infratentorial stroke
    Meng Dai, Jia Qiao, Xiaomei Wei, Huayu Chen, Zhonghui Shi, Zulin Dou
    NeuroImage: Clinical.2022; 35: 103104.     CrossRef
  • Characteristics of dysphagia among different lesion sites of stroke: A retrospective study
    Jia Qiao, Zhi-min Wu, Qiu-ping Ye, Meng Dai, Yong Dai, Zi-tong He, Zu-lin Dou
    Frontiers in Neuroscience.2022;[Epub]     CrossRef
  • Increased Cortical–Medulla Functional Connectivity is Correlated with Swallowing in Dysphagia Patients with Sub-Acute Infratentorial Stroke
    Meng Dai, Jia Qiao, Xiaomei Wei, Huayu Chen, Zhonghui Shi, Zulin Dou
    SSRN Electronic Journal .2022;[Epub]     CrossRef
  • Predictive factors of severity and persistence of oropharyngeal dysphagia in sub-acute stroke
    Alessandro De Stefano, Francesco Dispenza, Gautham Kulamarva, Giuseppina Lamarca, Antonio Faita, Antonio Merico, Giuseppe Sardanelli, Salvatore Gabellone, Antonio Antonaci
    European Archives of Oto-Rhino-Laryngology.2021; 278(3): 741.     CrossRef
  • Usefulness of the Modified Videofluoroscopic Dysphagia Scale in Choosing the Feeding Method for Stroke Patients with Dysphagia
    Byung Joo Lee, Hyoshin Eo, Changbae Lee, Donghwi Park
    Healthcare.2021; 9(6): 632.     CrossRef
  • The influence of pharyngeal width on post-stroke laryngeal aspiration
    Wonil Kang, Jane Chung, Jeongeun Lee, Kwang-Ik Jung, Woo-Kyoung Yoo, Suk Hoon Ohn
    NeuroRehabilitation.2021; 49(3): 435.     CrossRef
  • Use of the maximal phonation test for the screening of dysphagia in stroke patients: a preliminary study
    Ju-Young Lim, Young-Hwan Yoo, Chan-Hyuk Park, Kyung-Lim Joa, Han-Young Jung
    European Journal of Physical and Rehabilitation Medicine.2020;[Epub]     CrossRef
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  • 235 Download
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Proportion of Aspiration Pneumonia Cases Among Patients With Community-Acquired Pneumonia: A Single-Center Study in Korea
Inpyo Jeon, Gwang Pyo Jung, Han Gil Seo, Ju Seok Ryu, Tai Ryoon Han, Byung-Mo Oh
Ann Rehabil Med 2019;43(2):121-128.   Published online April 30, 2019
DOI: https://doi.org/10.5535/arm.2019.43.2.121
Objective
To investigate the proportion of aspiration pneumonia cases among patients with community-acquired pneumonia in Korea.
Methods
This retrospective study included patients with community-acquired pneumonia who had been admitted to the emergency department of a university-affiliated tertiary hospital in Gyeonggi Province, Korea between January 1, 2016 and December 31, 2016. Among these patients, those with aspiration pneumonia were identified using ICD-10 codes (J69.*). Patients with recurrent pneumonia were excluded, as were those who were immunocompromised. The proportion of cases of aspiration pneumonia was calculated, and the characteristics and clinical outcomes of patients with aspiration pneumonia and non-aspiration pneumonia were compared.
Results
The proportion of aspiration pneumonia cases among patients with community-acquired pneumonia was 14.2%. Patients with aspiration pneumonia were significantly more likely to be older (p<0.001) and male (p<0.001), and to have a higher confusion, uremia, respiratory rate, blood pressure, and age ≥65 years (CURB-65) score (p<0.001) as compared to patients with non-aspiration pneumonia. They were also more likely to require admission to the intensive care unit (p<0.001) and a longer hospital stay (p<0.001).
Conclusion
Aspiration pneumonia accounts for 14.2% of all cases of community-acquired pneumonia in Korea. These data may contribute to the establishment of healthcare strategies for managing aspiration pneumonia among Korean adults.

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    Kou Chin, Shuntaro Hiro, Momo Hirata, Mari Inoue, Ryo Nagasawa, Hiroshi Ishi, Yu Hara
    Journal of Clinical Question.2026;[Epub]     CrossRef
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    Akihito Ueda, Kanji Nohara
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    Jordi Almirall, Ramón Boixeda, Mari C. de la Torre, Marcial Cariqueo, Antoni Torres
    European Respiratory Review.2025; 34(178): 250037.     CrossRef
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    Akihito Ueda, Kanji Nohara
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  • Predictors and impact of aspiration pneumonia in patients undergoing esophagogastroduodenoscopy: national inpatient sample 2016–2020
    Jay Patel, Aalam Sohal, Hunza Chaudhry, Shivam Kalra, Isha Kohli, Ishandeep Singh, Dino Dukovic, Juliana Yang
    European Journal of Gastroenterology & Hepatology.2024; 36(3): 298.     CrossRef
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  • Predictive value of the videofluoroscopic swallowing study for long-term mortality in patients with subacute stroke
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    Medicine.2022; 101(4): e28623.     CrossRef
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    Jinwook Bahk, Kyunghee Jung-Choi
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Effect of Whole Body Horizontal Vibration Exercise in Chronic Low Back Pain Patients: Vertical Versus Horizontal Vibration Exercise
Heejae Kim, Bum Sun Kwon, Jin-Woo Park, Hojun Lee, Kiyeun Nam, Taejune Park, Yongjin Cho, Taeyeon Kim
Ann Rehabil Med 2018;42(6):804-813.   Published online December 28, 2018
DOI: https://doi.org/10.5535/arm.2018.42.6.804
Objective
To elucidate the effect of a 12-week horizontal vibration exercise (HVE) in chronic low back pain (CLBP) patients as compared to vertical vibration exercise (VVE).
Methods
Twenty-eight CLBP patients were randomly assigned to either the HVE or VVE group. All participants performed the exercise for 30 minutes each day, three times a week, for a total of 12 weeks. Altered pain and functional ability were evaluated using the visual analog scale (VAS) and Oswestry Disability Index (ODI), respectively. Changes in lumbar muscle strength, transverse abdominis (TrA) and multifidus muscle thicknesses, and standing balance were measured using an isokinetic dynamometer, ultrasonography, and balance parameters, respectively. These assessments were evaluated prior to treatment, 6 weeks and 12 weeks after the first treatment, and 4 weeks after the end of treatment (that is, 16 weeks after the first treatment).
Results
According to the repeated-measures analysis of variance, there were significant improvements with time on VAS, ODI, standing balance score, lumbar flexor, and extensor muscle strength (all p<0.001 in both groups) without any significant changes in TrA (p=0.153 in HVE, p=0.561 in VVE group) or multifidus (p=0.737 in HVE, p=0.380 in VVE group) muscle thickness. Further, there were no significant differences between groups according to time in any of the assessments. No adverse events were noticed during treatment in either group.
Conclusion
HVE is as effective as VVE in reducing pain, strengthening the lumbar muscle, and improving the balance and functional abilities of CLBP patients. Vibrational exercise increases muscle strength without inducing muscle hypertrophy.

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Clinical Importance of Peak Cough Flow in Dysphagia Evaluation of Patients Diagnosed With Ischemic Stroke
Sang Won Min, Se Hyun Oh, Ghi Chan Kim, Young Joo Sim, Dong Kyu Kim, Ho Joong Jeong
Ann Rehabil Med 2018;42(6):798-803.   Published online December 28, 2018
DOI: https://doi.org/10.5535/arm.2018.42.6.798
Objective
To investigate the relationship between peak cough flow (PCF), pulmonary function tests (PFT), and severity of dysphagia in patients with ischemic stroke.
Methods
This study included patients diagnosed with ischemic stroke, who underwent videofluoroscopic swallowing study (VFSS), PCF and PFT from March 2016 to February 2017. The dysphagia severity was assessed using the videofluoroscopic dysphagia scale (VDS). Correlation analysis of VDS, PFT and PCF was performed. Patients were divided into three groups based on VDS score. One-way ANOVA of VDS was performed to analyze PCF, forced vital capacity (FVC), forced expiratory volume in one second (FEV1), and age among the different groups.
Results
The correlation coefficients of VDS and PCF, VDS and FVC, and VDS and FEV1 were -0.836, -0.508, and -0.430, respectively, all of which were statistically significant at the level of p<0.001. The one-way ANOVA indicated statistically significant differences in PCF, FVC, FEV1, and age among the VDS groups. Statistically significant differences in VDS and age were observed between aspiration pneumoia and non-aspiration pneumonia groups.
Conclusion
Coughing is a useful factor in evaluating the risk of aspiration in dysphagia patients. Evaluation of respiratory and coughing function should be conducted during the swallowing assessment of patients with ischemic stroke.

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Case Report

Limitation of Intraoperative Transcranial Electrical Stimulation-Motor Evoked Potential Monitoring During Brain Tumor Resection Adjacent to the Primary Motor Cortex
Hui Jae Do, Han Gil Seo, Byung-Mo Oh, Chul-Kee Park, Jin Wook Kim, Young Doo Choi, Seung Hak Lee
Ann Rehabil Med 2018;42(5):767-772.   Published online October 31, 2018
DOI: https://doi.org/10.5535/arm.2018.42.5.767
Transcranial electrical stimulation-motor evoked potential (TES-MEP) is a valuable intraoperative monitoring technique during brain tumor surgery. However, TES can stimulate deep subcortical areas located far from the motor cortex. There is a concern about false-negative results from the use of TES-MEP during resection of those tumors adjacent to the primary motor cortex. Our study reports three cases of TES-MEP monitoring with false-negative results due to deep axonal stimulation during brain tumor resection. Although no significant change in TES-MEP was observed during surgery, study subjects experienced muscle weakness after surgery. Deep axonal stimulation of TES could give false-negative results. Therefore, a combined method of TES-MEP and direct cortical stimulation-motor evoked potential (DCS-MEP) or direct subcortical stimulation should be considered to overcome the limitation of TES-MEP.

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    Justin W. Silverstein, James Duehr, Sabena Vilaysom, Michael Schulder, Daniel G. Eichberg
    The Neurodiagnostic Journal.2024; 64(4): 203.     CrossRef
  • Short and long-term prognostic value of intraoperative motor evoked potentials in brain tumor patients: a case series of 121 brain tumor patients
    Justin W. Silverstein, Harshal A. Shah, Prashin Unadkat, Sabena Vilaysom, John A. Boockvar, David J. Langer, Jason A. Ellis, Randy S. D’Amico
    Journal of Neuro-Oncology.2023; 161(1): 127.     CrossRef
  • Real world demonstration of hand motor mapping using the structural connectivity atlas
    Karol Osipowicz, Christos Profyris, Alana Mackenzie, Peter Nicholas, Peter Rudder, Hugh M. Taylor, Isabella M. Young, Angus W. Joyce, Lewis Dobbin, Onur Tanglay, Lerroy Thompson, Tshimollo Mashilwane, Michael E. Sughrue, Stephane Doyen
    Clinical Neurology and Neurosurgery.2023; 228: 107679.     CrossRef
  • Usefulness of Transcranial Motor Evoked Potential in Clipping Surgery for Cerebral Aneurysms-Introduction of a New Protocol for Stable Monitoring
    Tatsuya SASAKI, Kensuke MURAKAMI, Atsushi SAITO, Shinya HARYU, Masayuki KAMEYAMA, Yoshiharu TAKAHASHI, Satoru TAKAMURO, Nana KATO, Toshiki ENDO
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Original Articles
Influence of Hip Fracture on Knee Pain During Postoperative Rehabilitation
Hee-Ju Kim, Seong Jae Lee, Jung Keun Hyun, Seo-Young Kim, Tae Uk Kim
Ann Rehabil Med 2018;42(5):682-689.   Published online October 31, 2018
DOI: https://doi.org/10.5535/arm.2018.42.5.682
Objective
To investigate whether fracture type, surgical procedure, or fracture grade affect knee pain during postoperative rehabilitation after a hip fracture.
Methods
We conducted a retrospective case-controlled study of 139 patients during postoperative rehabilitation after surgery for hip fractures. Patients were divided into two groups: patients experiencing knee pain during the first week of postoperative rehabilitation, and patients without knee pain. We compared the types of fracture, surgical procedure, and fracture grade between the two groups.
Results
We enrolled 52 patients (37.4%) with knee pain during the first weeks of postoperative rehabilitation. For type of fracture, knee pain was more common with intertrochanteric fracture than with femur neck fracture (48.8% vs. 21.1%, respectively; p=0.001). For the surgical procedure, there was no significant difference between the groups. For the fracture grade, the grades classified as unstable fractures were more common in the group of intertrochanteric fracture patients with knee pain than in those without knee pain (74.1% vs. 36.4%, respectively; p=0.002).
Conclusion
Intertrochanteric fracture affected knee pain after hip fracture surgery more than did femur neck fracture, particularly in unstable fractures. Furthermore, there was no difference in each fracture type according to the surgical procedure. Careful examination and management for knee pain is needed in patients with hip fracture surgery.

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  • High Prevalence of Symptomatic Knee Osteoarthritis Among Patients Who Have Fragility Hip Fractures
    Korawish Mekariya, Ekasame Vanitcharoenkul, Pojchong Chotiyarnwong, Nath Adulkasem, Aasis Unnanuntana
    The Journal of Arthroplasty.2025; 40(8): 2179.     CrossRef
  • Post-hip fracture knee pain in older adults: a narrative review
    Yoichi Kaizu, Kazuhiro Miyata
    Aging Advances.2025; 2(2): 62.     CrossRef
  • Post‐hip‐fracture knee pain in older adults prolongs their hospital stays: A retrospective analysis using propensity score matching
    Yoichi Kaizu, Kazuhiro Miyata, Hironori Arii
    Physiotherapy Research International.2024;[Epub]     CrossRef
  • Predictors of post‐hip fracture knee pain in hospitalized older adults with intertrochanteric femoral fracture
    Yoichi Kaizu, Kazuhiro Miyata, Hironori Arii
    PM&R.2023; 15(5): 563.     CrossRef
  • Femoral morphology is associated with development of knee pain after hip fracture injury among older adults: A nine-year retrospective study
    Yoichi Kaizu, Kazuhiro Miyata, Hironori Arii, Masayuki Tazawa, Takehiko Yamaji
    Journal of Orthopaedics.2021; 24: 190.     CrossRef
  • Inpatient knee pain after hip fracture surgery affects gait speed in older adults: A retrospective chart‐referenced study
    Yoichi Kaizu, Kazuhiro Miyata, Hironori Arii, Takehiko Yamaji
    Geriatrics & Gerontology International.2021; 21(9): 830.     CrossRef
  • Thirty-Day Readmission After Radical Gastrectomy for Gastric Cancer: A Meta-analysis
    Zhang Dan, Deng YiNan, Yang ZengXi, Wang XiChen, Pan JieBin, Yin LanNing
    Journal of Surgical Research.2019; 243: 180.     CrossRef
  • 10,247 View
  • 174 Download
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Motor and Sensory Function as a Predictor of Respiratory Function Associated With Ventilator Weaning After High Cervical Cord Injury
Tae Wan Kim, Jung Hyun Yang, Sung Chul Huh, Bon Il Koo, Jin A Yoon, Je Sang Lee, Hyun-Yoon Ko, Yong Beom Shin
Ann Rehabil Med 2018;42(3):457-464.   Published online June 27, 2018
DOI: https://doi.org/10.5535/arm.2018.42.3.457
Objective
To analyze the respiratory function of high cervical cord injury according to ventilator dependence and to examine the correlations between diaphragm movement found on fluoroscopy and sensory and motor functions.
Methods
A total of 67 patients with high cervical spinal cord injury (SCI), admitted to our hospital were enrolled in the study. One rehabilitation physician performed sensory and motor examinations on all patients while each patient was in the supine position on the American Spinal Injury Association (ASIA) standard. In addition, fluoroscopic diaphragm movement studies and bedside spirometry were performed.
Results
Bedside spirometry and diaphragm fluoroscopic tests were analyzed according to ventilator dependence. Forced vital capacity and maximal inspiratory pressure were significantly higher in the ventilator weaned group. Natural breathing during the fluoroscopic diaphragm examinations and ventilator weaning showed statistical significance with the movement on the right, while deep breathing showed statistical significance with the movement on both sides. Deep breathing movement has correlation with the C5 key muscle. Diaphragm movement has correlation with right C3 and bilateral C4 sensory functions.
Conclusion
The present expansion study showed that, through simple bedside physical examinations, rehabilitation physicians could relatively easily predict diaphragm movement and respiratory function recovery, which showed significance with ventilator weaning in patients with high cervical SCI.

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  • A multimodal respiratory weaning intervention for adult critical care patients mechanically ventilated with cervical spinal cord injury: a quality improvement project
    Tammy J. Lea, Adam J. C. Harriman, James Hodson, Jonathan Weblin
    Spinal Cord.2025; 63(11): 579.     CrossRef
  • Predicting extubation in patients with traumatic cervical spinal cord injury using the diaphragm electrical activity during a single maximal maneuver
    Rui Zhang, Xiaoting Xu, Hui Chen, Jennifer Beck, Christer Sinderby, Haibo Qiu, Yi Yang, Ling Liu
    Annals of Intensive Care.2023; 13(1): 122.     CrossRef
  • Respiratory Complications and Weaning Considerations for Patients with Spinal Cord Injuries: A Narrative Review
    Kristopher A. Hendershot, Kristine H. O’Phelan
    Journal of Personalized Medicine.2022; 13(1): 97.     CrossRef
  • Separation from mechanical ventilation and survival after spinal cord injury: a systematic review and meta-analysis
    Annia F. Schreiber, Jacopo Garlasco, Fernando Vieira, Yie Hui Lau, Dekel Stavi, David Lightfoot, Andrea Rigamonti, Karen Burns, Jan O. Friedrich, Jeffrey M. Singh, Laurent J. Brochard
    Annals of Intensive Care.2021;[Epub]     CrossRef
  • 11,015 View
  • 184 Download
  • 4 Web of Science
  • 4 Crossref
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