Objective To compare the effects of low intensity ultrasound (LIUS), traditional exercise therapy (TET), low level laser therapy (LLLT) and TET on temporomandibular joint (TMJ) pain and trismus following recovery from head and neck cancer (HNC).
Methods Sixty participants following, who had experienced HNC, were randomly allocated to three groups of 20 people each. Each group received different therapy. Group A received LIUS and TET; group B received LLLT and TET; while group C received TET. All 60 participants were evaluated under the visual analog scale (VAS), the University of Washington Quality of Life questionnaire (UW-QOL) and the Vernier caliper scale (VCS) at the beginning of the therapies and after 4 weeks.
Results ANOVA test revealed significant improvements across all three groups with outcomes of p<0.05. The results of the UW-QOL questionnaire showed a significant difference between groups A, B and C in favor of group A (p<0.05). The VAS results showed a more improvement in group A as compared to group B (p<0.05), while there was no statistical difference between groups B and C (p>0.05). The VCS results showed more improvement for the individuals in group B as compared to those in group C (p<0.05), while there was minimal difference between groups A and B (p>0.05).
Conclusion The LIUS and TET are more effective than LLLT and/or TET in reducing TMJ pain and trismus following HNC.
Citations
Citations to this article as recorded by
Efficiency of different treatment modalities on radiation induced trismus for maxillofacial cases: a parallel randomized clinical trial Marwa Ahmed Aboelez, Abdallah Mohammed Ibrahim, Mohammed A ElSawy, Nermeen El sayed El-Khamisy BMC Oral Health.2025;[Epub] CrossRef
Rehabilitation strategies for trismus post oral cancer treatment: Progress in the study of mouth opening exercises Ling Yang, Guihua Hao, Lili Hou, Wenyu Yang Journal of Stomatology, Oral and Maxillofacial Surgery.2024; 125(6): 101796. CrossRef
Assessment of Integrative Therapeutic Methods for Improving the Quality of Life and Functioning in Cancer Patients—A Systematic Review Mădălina Gabriela Iliescu, Liliana-Elena Stanciu, Andreea-Bianca Uzun, Adelina-Elena Cristea, Irina Motoască, Laszlo Irsay, Dan Marcel Iliescu, Titus Vari, Alina Deniza Ciubean, Bogdan Marian Caraban, Nicolae Ciufu, Olgun Azis, Viorela Mihaela Ciortea Journal of Clinical Medicine.2024; 13(5): 1190. CrossRef
Photobiomodulation combination therapy as a new insight in neurological disorders: a comprehensive systematic review Narmin Farazi, Hanieh Salehi-Pourmehr, Fereshteh Farajdokht, Javad Mahmoudi, Saeed Sadigh-Eteghad BMC Neurology.2024;[Epub] CrossRef
Exercise adherence for patients with trismus after head and neck cancer treatment Emma Charters, Jamie Loy, Ashleigh R. Sharman, Kai Cheng, Masako Dunn, Jonathan Clark Head & Neck.2024; 46(11): 2717. CrossRef
A Narrative Review on Pain Management in Head and Neck Cancer: Integrating Multimodal Analgesia and Interventional Procedures Farnad Imani, Saleh Mohebbi, Masood Mohseni, Behnaz Karimi, Saeid Rahimi, Gholam Ali Dikafraz Shokooh Anesthesiology and Pain Medicine.2024;[Epub] CrossRef
Exercise therapy to treat trismus in a patient with head neck cancer: A case report Soumyajit Mandal, Subhajit Mandal, Deepika Malik, Kanika Thakur, Aksh Chahal Journal of Society of Indian Physiotherapists.2024; 8(1): 38. CrossRef
Effect of transcutaneous electrical nerve stimulation and Rocabado exercises on temporomandibular joint dysfunction after head and neck surgeries Rana M. M. Elattar, Haidy Nady Ashem, Ashraf E. M. Elsebaie, Zeinab A. Ali, Khadra M. Ali Fizjoterapia Polska.2024; 24(5): 220. CrossRef
Photobiomodulation therapy for the prevention of acute radiation dermatitis: a systematic review and meta-analysis Margherita Gobbo, Victoria Rico, Gustavo Nader Marta, Saverio Caini, Julie Ryan Wolf, Corina van den Hurk, Mara Beveridge, Henry Lam, Pierluigi Bonomo, Edward Chow, Tara Behroozian Supportive Care in Cancer.2023;[Epub] CrossRef
Quality assessment of PBM protocols for oral complications in head and neck cancer patients: part 2 Margherita Gobbo, Praveen R. Arany, Elisabetta Merigo, René-Jean Bensadoun, Alan Roger Santos-Silva, Luiz Alcino Gueiros, Giulia Ottaviani Supportive Care in Cancer.2023;[Epub] CrossRef
Effects of a program consisting of strain/counterstrain technique, phonophoresis, heat therapy, and stretching in patients with temporomandibular joint dysfunction Insha Azam, Aksh Chahal, Gaurav Kapoor, Pooja Chaudhuri, Ahmad H. Alghadir, Masood Khan, Faizan Z. Kashoo, Vandana Esht, Mohammed M. Alshehri, Mohammad Abu Shaphe, Abdur Raheem Khan, Gurjant Singh Medicine.2023; 102(32): e34569. CrossRef
Photobiomodulation therapy in the treatment of radiotherapy-related trismus of the head and neck Marcela Maria Fontes Borges, Cássia Emanuella Nóbrega Malta, Anna Clara Aragão Matos Carlos, André Alves Crispim, José Fernando Bastos de Moura, Lievin Matos Rebouças, Bruna Carolina Coelho da Silva, Clarissa Gondim Picanço de Albuquerque, Paulo Goberlâni Lasers in Medical Science.2023;[Epub] CrossRef
Ultrasound therapy in the management of temporomandibular joint disorders Mohamed Asan, Shruthi Hegde, Babu Subhas, Vidya Ajila, Viabhav Pandita Acta stomatologica Naissi.2023; 39(87): 2605. CrossRef
Quality Assessment of PBM Protocols for Oral Complications in Head and Neck Cancer Patients: Part 1 Margherita Gobbo, Elisabetta Merigo, Praveen R. Arany, René-Jean Bensadoun, Alan Roger Santos-Silva, Luiz Alcino Gueiros, Giulia Ottaviani Frontiers in Oral Health.2022;[Epub] CrossRef
Métodos e Técnicas Não Farmacológicos no Tratamento da Dor Oncológica: Revisão Sistemática da Literatura Natali dos Santos Nascimento, Amanda Tinôco Neto Santos, Priscila Godoy Januário Martins Alves Revista Brasileira de Cancerologia.2022;[Epub] CrossRef
Interventions for Trismus in Head and Neck Cancer Patients: A Systematic Review of Randomized Controlled Trials Shuzhen Chee, Yasmeen M. Byrnes, Kevin T. Chorath, Karthik Rajasekaran, Jie Deng Integrative Cancer Therapies.2021;[Epub] CrossRef
The outcomes of ultrasonic and laser therapy in case of temporomandibular disorders – an evidence based update Marius NEGUCIOIU, Andreea KUI, Mihai MITARIU, Manuela MANZIUC, Daniela CONDOR, Loredana MITARIU, Smaranda BUDURU Balneo and PRM Research Journal.2021; 12(3): 210. CrossRef
Role of Manual Therapy for Neck Pain and Quality of Life in Head and Neck Cancer Survivors: A Systematic Review Renu B Pattanshetty, Sayali Nandkumar Patil Indian Journal of Palliative Care.2021; 28: 99. CrossRef
Interprofessional Collaboration in Dentistry: Role of physiotherapists to improve care and outcomes for chronic pain conditions and sleep disorders Alberto Herrero Babiloni, Jacqueline T. A. T. Lam, Fernando G. Exposto, Gabrielle Beetz, Catherine Provost, Dany H. Gagnon, Gilles J. Lavigne Journal of Oral Pathology & Medicine.2020; 49(6): 529. CrossRef
Restricted Mouth Opening in Head and Neck Cancer: Etiology, Prevention, and Treatment Waseem A. Abboud, Sharon Hassin-Baer, Eran E. Alon, Iris Gluck, Alex Dobriyan, Uri Amit, Ran Yahalom, Noam Yarom JCO Oncology Practice.2020; 16(10): 643. CrossRef
Objective This study was performed to investigate the effects of low-level laser irradiation on the dorsal horn cell activities in the rats with experimental muscle pain. Method: Experimental muscle pain was induced by repeated injections of acidic saline into the gastrocnemius muscle in thirty Sprague-Dawley rats. Activities of ipsilateral dorsal horn cells were recorded with a glass microelectrode at L2-L4 spinal cord level before and after low-level laser irradiation on the injected leg. Cells were categorized as wide dynamic range (WDR) and high threshold (HT) cells by the response to the cotton, vonFrey filament, and forceps stimulation at the receptive area.Results: The spontaneous and mechanically evoked activities of WDR and HT cells were significantly increased in the muscle pain models. Low-level laser irradiation reduced mechanically evoked activities of WDR and HT cells. This effect was maximal at 20 minutes after irradiation and then returned to pre-treatment level in 40∼50 minutes. Conclusion: The low-level laser irradiation was effective for the management of muscle pain by reducing activities of dorsal horn cells. Low-level laser might be clinically used for the treatment of local and referred pain of muscle origin. (J Korean Acad Rehab Med 2005; 29: 513-520)
Objective We examined the effect of low power laser irradiation (LPLI) on the proliferation and differentiation of PC12 nerve cells. Method: After seeding 4⁓105 PC12 nerve cells each in the 24 well-culture dishes, we cultured them for 6 days with RPMI1640 media. LPLI (650 nm, 5 mW, 5 sec) was applied for 1 day, 2 days and 3 days (1, 2 and 3-day-LPLI groups) consecutively. For the degree of proliferation of PC12 nerve cells, we compared the total cell number at 6th day after LPLI by MTT cell proliferation assay. For the degree of differentiation, we compared the length of neurite out- growth and the expression of RT97 at 6th day after adding nerve growth factor on each group. Results: The total cell numbers were increased significantly after LPLI, but those increments were not significant among 1, 2, and 3-day-LPLI groups. The numbers of the differentiated PC12 nerve cells and the expressions of RT97 were diminished serially according to the number of days of LPLI. Conclusion: We conclude that LPLI increased the proliferation and decreased the differentiation of PC12 nerve cells. We could suggest that single or short-term use of LPLI on the injured nerve should be helpful for enhancing the neural regeneration in vivo. (J Korean Acad Rehab Med 2005; 29: 419-423)
Objective This study was designed to investigate the mechanism of the primary afferent input to spread of contralateral hyperalgesia in the persistent muscle pain model in the rat.Method: Muscle pain was induced by twice repeated intramuscular injections of pH 6.0 buffered saline into the unilateral gastrocnemius muscle of the rats. Change of mechanical withdrawal threshold to von-Frey filament was measured after ipsilateral laser irradiation, anesthetic blockade with lidocaine and dorsal rhizotomy (L2∼L6) to reduce primary afferent input from the tissue injury. Results: Bilateral persistent mechanical hyperalgesia in the hind paw was evoked after second injection. Ipsilateral laser irradiation, lidocaine injection and dorsal rhizotomy had no effect on the contralateral spread of mechanical hyperalgesia.Conclusion: These results suggest that contralateral hyperalgesia was produced by, but didn't need to be maintained by inputs from an injury. Therefore, central nervous systems are responsible for the contralateral spread of hyperalgesia. (J Korean Acad Rehab Med 2004; 28: 477-482)
Objective To verify the effect of low energy laser irradiation (LELI) on the regeneration of injured sciatic nerve of the rat by showing the functional improvement and the elevated immunoreactivities (IRs) of growth-associated protein 43 (GAP-43). Method: Twenty rats, which had standardized compression injuries to the sciatic nerves, received the calculated LELI therapy immediately after the nerve injury and four consecutive days. The functional status was evaluated by sciatic functional index (SFI), and GAP-43-IRs was evaluated by immunohistochemistry and RT-PCR. Results: The SFI was recovered in LELI rats faster than in the control group. Although expression of GAP-43 in the injured sciatic nerve was increased both in the LELI and control groups, the intensities of GAP-43-IRs were much greater in LELI treated group at 1 and 3 weeks after nerve injury. Both SFI and GAP-43-IRs reached the same level at 5 weeks after the nerve injury. Conclusion: LELI enhanced the neural regeneration after experimentally induced sciatic nerve injury at the early stage of recovery. Considering the effect of LELI on nerve regeneration was not fully explained until now, this study could suggest the meaningful explanation on the mechanism of LELI effectiveness on neural regeneration. (J Korean Acad Rehab Med 2004; 28: 64-70)
First
Prev
