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"Intervertebral disc displacement"

Original Articles

Sequential Activation of AMPA Receptors and Glial Cells in a Pain Model of Lumbar Spine Disc Herniation
Dong Gyu Kwak, Dong Gyu Lee
Ann Rehabil Med 2020;44(5):343-352.   Published online September 28, 2020
DOI: https://doi.org/10.5535/arm.19202
Objective
To investigate the glial cell and AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptor activity after surgery for disc herniation pain model.
Methods
In total, 83 Sprague-Dawley rats were randomly assigned to the following groups: control (n=16), sham-operated (n=4), rats for pain behavior evaluation (n=3), nucleus pulposus-exposed groups for AMPA receptors (n=30), and glial cell (n=30). The rats were tested for mechanical allodynia; immunohistochemical staining for AMPA receptors (GluA1 and GluA2) and glial cells (OX-42 and glial fibrillary acid protein [GFAP]) in the spinal dorsal horn was performed on postoperative days 3, 7, and 14.
Results
Mechanical withdrawal thresholds decreased after surgery, and this effect was maintained for up to 14 days. Immunohistochemical expression of GluA1 and GluA2 in the spinal dorsal horn had increased quantitatively on postoperative days 3 and 7 (p<0.05) to levels similar to that of the controls on postoperative day 14. Moreover, immunohistochemical expression of OX-42 and GFAP showed similar changes to AMPA receptors after surgery. Although the activity of AMPA receptors and glial cells achieved normalcy, the mechanical withdrawal threshold of the hind paw remained decreased 38 days after surgery.
Conclusion
The rat model of lumbar disc herniation showed increased expression of AMPA receptor and glial cell activity in the spinal dorsal horn 3 and 7 days after surgery, which deceased to control levels at 14 days. The AMPA receptors and glial cell activations showed similar patterns after disc herniation surgery.

Citations

Citations to this article as recorded by  
  • Regulating AMPA Receptors with Isoxazole-4-Carboxamide Derivatives: An Electrophysiological Study
    Mohammad Qneibi, Mohammed Hawash, Sosana Bdir, Mohammad Bdair, Tala Idais, Iyas Sarhan, Joud Touqan
    Journal of Xenobiotics.2025; 15(2): 40.     CrossRef
  • Predictive value of S100B and brain derived neurotrophic factor for radiofrequency treatment of lumbar disc prolapse
    Wael Fathy, Mona Hussein, Rehab Magdy, Hatem Elmoutaz, Neveen A Youssef, Marwa F Abd Alla, Ahmed M El Shaarawy, Mohamed Abdelbadie
    BMC Anesthesiology.2024;[Epub]     CrossRef
  • Animal Models of Intervertebral Disc Diseases: Advantages, Limitations, and Future Directions
    Jin Young Hong, Hyunseong Kim, Wan-Jin Jeon, Changhwan Yeo, Hyun Kim, Junseon Lee, Yoon Jae Lee, In-Hyuk Ha
    Neurology International.2024; 16(6): 1788.     CrossRef
  • 4,604 View
  • 100 Download
  • 3 Web of Science
  • 3 Crossref
Does Adequate Lumbar Segmental Motion Reflect Recovery Process in Acute Lumbar Disc Herniation?
Hyuntae Kim, Ho Joong Jung, Minsun Kim, Seong-Eun Koh, In-Sik Lee
Ann Rehabil Med 2019;43(1):38-44.   Published online February 28, 2019
DOI: https://doi.org/10.5535/arm.2019.43.1.38
Objective
To investigate if the extent of lumbar segmental motion is correlated with the recovery process in the form of pain intensity in patients with acute single level lumbar disc herniation (LDH).
Methods
A retrospective review of medical records was performed on patients presented with acute low back pain from January 2011 to December 2017. With prerequisites of undergoing both lumbar spine magnetic resonance imaging and functional radiography, patients with etiologies other than single level LDH were excluded. A total of 46 patients were selected, including 27 patients with disc herniation at L4-5 level and 19 patients at L5-S1 level. Pearson correlation analysis of pain intensity against segmental range of motion (sROM) and percentage of sROM of each lumbar segment was performed at the initial evaluation point and follow-ups.
Results
Serial documentation of pain intensity and functional radiography exhibited an inverse correlation between changes in visual analogue scale (VAS) and sROM in single level LDH at L4-5 level (r=-0.69, p<0.05). In addition, percentage of sROM showed a negative correlation with pain intensity at the aforementioned segment (r=-0.74, p<0.05). Initial pain intensity was also inversely correlated to sROM of the affected segment (r=-0.83, p<0.01 at L4-5; r=-0.82, p<0.05 at L5-S1).
Conclusion
Improvement in sagittal mobility of the affected segment in LDH adequately reflected mitigation of low back pain during the recovery process. This conjunction could illustrate that the involved segment is overcoming natural immobilization, evidently demonstrating an inverse relationship between initial pain intensity and limitation of sagittal range of motion.

Citations

Citations to this article as recorded by  
  • Relationships and representations of brain structures, connectivity, dynamics and functions
    Oliver Schmitt
    Progress in Neuro-Psychopharmacology and Biological Psychiatry.2025; 138: 111332.     CrossRef
  • 5,552 View
  • 97 Download
  • 1 Crossref

Case Report

Posterior Epidural Migration of a Lumbar Intervertebral Disc Fragment Resembling a Spinal Tumor: A Case Report
Hyojun Kim, Bum Sun Kwon, Jin-Woo Park, Ho Jun Lee, Jung Whan Lee, Eun Kyoung Lee, Tae June Park, Hee Jae Kim, Yongjin Cho, Taeyeon Kim, Kiyeun Nam
Ann Rehabil Med 2018;42(4):621-625.   Published online August 31, 2018
DOI: https://doi.org/10.5535/arm.2018.42.4.621
Posterior epidural migration of a lumbar intervertebral disc fragment (PEMLIF) is uncommon because of anatomical barriers. It is difficult to diagnose PEMLIF definitively because of its relatively rare incidence and the ambiguity of radiological findings resembling spinal tumors. This case report describes a 76-year-old man with sudden-onset weakness and pain in both legs. Electromyography revealed bilateral lumbosacral polyradiculopathy with a mass-like lesion in L2-3 dorsal epidural space on lumbosacral magnetic resonance imaging (MRI). The lesion showed peripheral rim enhancement on T1-weighted MRI with gadolinium administration. The patient underwent decompressive L2-3 central laminectomy, to remove the mass-like lesion. The excised lesion was confirmed as an intervertebral disc. The possibility of PEMLIF should be considered when rim enhancement is observed in the epidural space on MRI scans and electrodiagnostic features of polyradiculopathy with sudden symptoms of cauda equina syndrome.

Citations

Citations to this article as recorded by  
  • Posterior epidural migration of thoracic and lumbar disc material: a comprehensive 63-year systematic review with anatomical perspectives
    Shafi Hamid, Madison Kropuenske, Salma Zahran, Ehsan Alimohammadi
    Neurosurgical Review.2025;[Epub]     CrossRef
  • Posterior epidural migration of herniated disc: A case series and literature review
    Maria Ilaria Borruto, Andrea Perna, Domenico Alessandro Santagada, Calogero Velluto, Maurizio Genitiempo, Francesco Ciro Tamburrelli, Luca Proietti
    Journal of Neurosciences in Rural Practice.2025; 16: 1.     CrossRef
  • Sequestered Lumbar Disc Mimicking Psoas Abscess: A Case Report
    Shu Suzuki, Kazuya Okita, Kazuki Abe, Mizuka Suzuki, Yasunobu Takaki
    Cureus.2025;[Epub]     CrossRef
  • Gadolinium-Enhanced 3-Dimensional MRI for Diagnosis and Surgical Planning of Posterior Epidural Migration of Lumbar Disc Fragment
    Yoshinao Koike, Tomomichi Kajino, Shinya Dobashi, Norimasa Iwasaki
    JBJS Case Connector.2024;[Epub]     CrossRef
  • Posterior and anterior epidural and intradural migration of the sequestered intervertebral disc: Three cases and review of the literature
    Daphne J. Theodorou, Stavroula J. Theodorou, Yousuke Kakitsubata, Evangelos I. Papanastasiou, Ioannis D. Gelalis
    The Journal of Spinal Cord Medicine.2022; 45(2): 305.     CrossRef
  • Posterior epidural intervertebral disc migration and sequestration: A systematic review
    Paolo Palmisciano, Kishore Balasubramanian, Gianluca Scalia, Navraj S. Sagoo, Ali S. Haider, Othman Bin Alamer, Vishal Chavda, Bipin Chaurasia, Harsh Deora, Maurizio Passanisi, Valerio Da Ros, Giuseppe R. Giammalva, Rosario Maugeri, Domenico G. Iacopino,
    Journal of Clinical Neuroscience.2022; 98: 115.     CrossRef
  • A Review of the Diagnostic Features of Posteriorly Migrated Lumbar Discs with Reports of Two Cases
    Ajaya Kumar Ayyappan Unnithan
    Neurology India.2022; 70(3): 1213.     CrossRef
  • Sequestrated Lumbar Disc Herniation Mimicking Spinal Neoplasm
    Faisal Konbaz, Sami I Aleissa, Fahad Al Helal, Majed Abaalkhail, Waleed Alrogy, Abrar Bin Dohaim, Nasser Albishi
    Cureus.2021;[Epub]     CrossRef
  • Posterior epidural sequestrated disc presenting with contralateral radiculopathy: a very rare case
    Withawin Kesornsak, Kanthika Wasinpongwanich, Verapan Kuansongtham
    Spinal Cord Series and Cases.2021;[Epub]     CrossRef
  • Dorsal migration of lumbar disc fragments causing cauda equina syndromes: A three case series and literature review
    Shawn Singh Rai, Carlos Rodrigo Goulart, Sepehr Lalezari, Michael Anthony Galgano, Satish Krishnamurthy
    Surgical Neurology International.2020; 11: 175.     CrossRef
  • Posterior epidural migration of herniated lumbar disc fragment: a literature review
    Alaa Eldin Elsharkawy, Anne Hagemann, Peter Douglas Klassen
    Neurosurgical Review.2019; 42(4): 811.     CrossRef
  • 6,947 View
  • 90 Download
  • 9 Web of Science
  • 11 Crossref

Original Articles

Ultrasonography Evaluation of Vulnerable Vessels Around Cervical Nerve Roots During Selective Cervical Nerve Root Block
Hoon Hoon Lee, Donghwi Park, Yoongul Oh, Ju Seok Ryu
Ann Rehabil Med 2017;41(1):66-71.   Published online February 28, 2017
DOI: https://doi.org/10.5535/arm.2017.41.1.66
Objective

To evaluate the prevalence of vulnerable blood vessels around cervical nerve roots before cervical nerve root block in the clinical setting.

Methods

This retrospective study included 74 patients with cervical radiculopathy who received an ultrasonography-guided nerve block at an outpatient clinic from July 2012 to July 2014. Before actual injection of the steroid was performed, we evaluated the vulnerable blood vessels around each C5, C6, and C7 nerve root of each patient's painful side, with Doppler ultrasound.

Results

Out of 74 cases, the C5 level had 2 blood vessels (2.7%), the C6 level had 4 blood vessels (5.45%), and the C7 level had 6 blood vessels (8.11%) close to each targeted nerve root. Moreover, the C5 level had 2 blood vessels (2.7%), the C6 level 5 blood vessels (6.75%), and the C7 level had 4 blood vessels (5.45%) at the site of an imaginary needle's projected pathway to the targeted nerve root, as revealed by axial transverse ultrasound imaging with color Doppler imaging. In total, the C5 level had 4 blood vessels (5.45%), the C6 level 9 blood vessels (12.16%), and the C7 level 10 had blood vessels (13.51%) either at the targeted nerve root or at the site of the imaginary needle's projected pathway to the targeted nerve root. There was an unneglectable prevalence of vulnerable blood vessels either at the targeted nerve root or at the site of the needle' projected pathway to the nerve root. Also, it shows a higher prevalence of vulnerable blood vessels either at the targeted nerve root or at the site of an imaginary needle's projected pathway to the nerve root as the spinal nerve root level gets lower.

Conclusion

To prevent unexpected critical complications involving vulnerable blood vessel injury during cervical nerve root block, it is recommended to routinely evaluate for the presence of vulnerable blood vessels around each cervical nerve root using Doppler ultrasound imaging before the cervical nerve root block, especially for the lower cervical nerve root level.

Citations

Citations to this article as recorded by  
  • Ultrasound-Guided Selective Cervical Root Block in Spondylotic Radiculopathy: Advantages and Safety
    Dong Gyu Lee
    Clinical Pain.2023; 22(2): 61.     CrossRef
  • A prospective randomized comparison of the efficacy of standard antiviral therapy versus ultrasound-guided thoracic paravertebral block for acute herpes zoster
    Yingchao Ma, Bingsi Li, Lei Sun, Xin He, Shuang Wu, Fan Shi, Li Niu
    Annals of Medicine.2022; 54(1): 369.     CrossRef
  • Diagnosis and Treatment of Cervical Spondylotic Radiculopathy Using Selective Nerve Root Block (SNRB): Where are We Now?
    Dongfang Yang, Lichen Xu, Yutong Hu, Weibing Xu
    Pain and Therapy.2022; 11(2): 341.     CrossRef
  • Remnant Tumor Margin as Predictive Factor for Its Growth After Incomplete Resection of Cervical Dumbbell-Shaped Schwannomas
    Kazuya Kitamura, Narihito Nagoshi, Osahiko Tsuji, Satoshi Suzuki, Satoshi Nori, Eijiro Okada, Mitsuru Yagi, Morio Matsumoto, Masaya Nakamura, Kota Watanabe
    Neurospine.2022; 19(1): 32.     CrossRef
  • An open-label non-inferiority randomized trail comparing the effectiveness and safety of ultrasound-guided selective cervical nerve root block and fluoroscopy-guided cervical transforaminal epidural block for cervical radiculopathy
    Xiaohong Cui, Di Zhang, Yongming Zhao, Yongsheng Song, Liangliang He, Jian Zhang
    Annals of Medicine.2022; 54(1): 2669.     CrossRef
  • Ultrasound-guided cervical selective nerve root injections: a narrative review of literature
    Reza Ehsanian, Byron J Schneider, David J Kennedy, Eugene Koshkin
    Regional Anesthesia & Pain Medicine.2021; 46(5): 416.     CrossRef
  • Procedimentos minimamente invasivos na coluna vertebral
    Hazem Adel Ashmawi, André Marques Mansano
    Revista Paulista de Reumatologia.2021; (2021 abr-j): 61.     CrossRef
  • Vascular Evaluation around the Cervical Nerve Roots during Ultrasound-Guided Cervical Nerve Root Block
    Shizumasa Murata, Hiroshi Iwasaki, Yuta Natsumi, Hiroshi Minagawa, Hiroshi Yamada
    Spine Surgery and Related Research.2020; 4(1): 18.     CrossRef
  • Ultrasound‐Guided Cervical Nerve Root Block for the Treatment of Acute Cervical Herpes Zoster: A Randomized Controlled Clinical Study
    Shuyue Zheng, Xiuhua Li, Xiaohui Yang, Liangliang He, Yanyan Xue, Zhanmin Yang
    Pain Practice.2019; 19(5): 500.     CrossRef
  • Cervical Ultrasound Utilization in Selective Cervical Nerve Root Injection for the Treatment of Cervical Radicular Pain: a Review
    Reza Ehsanian, David J. Kennedy, Byron Schneider
    Current Physical Medicine and Rehabilitation Reports.2019; 7(4): 386.     CrossRef
  • 6,945 View
  • 125 Download
  • 8 Web of Science
  • 10 Crossref
The Prognostic Value of Enhanced-MRI and Fluoroscopic Factors for Predicting the Effects of Transforaminal Steroid Injections on Lumbosacral Radiating Pain
Yun Suk Jung, Jee Hyun Suh, Ha Young Kim, Kyunghoon Min, Yoongul Oh, Donghwi Park, Ju Seok Ryu
Ann Rehabil Med 2016;40(6):1071-1081.   Published online December 30, 2016
DOI: https://doi.org/10.5535/arm.2016.40.6.1071
Objective

To investigate the predictive value of enhanced-magnetic resonance imaging (MRI) and fluoroscopic factors regarding the effects of transforaminal epidural steroid injections (TFESIs) in low back pain (LBP) patients with lumbosacral radiating pain.

Methods

A total of 51 patients who had LBP with radiating pain were recruited between January 2011 and December 2012. The patient data were classified into the two groups ‘favorable group’ and ‘non-favorable group’ after 2 weeks of follow-up results. The favorable group was defined as those with a 50%, or more, reduction of pain severity according to the visual analogue scale (VAS) for back or leg pain. The clinical and radiological data were collected for univariate and multivariate analyses to determine the predictors of the effectiveness of TFESIs between the two groups.

Results

According to the back or the leg favorable-VAS group, the univariate analysis revealed that the corticosteroid approach for the enhanced nerve root, the proportion of the proximal flow, and the contrast dispersion of epidurography are respectively statistically significant relative to the other factors. Lastly, the multiple logistic regression analysis showed a significant association between the corticosteroid approach and the enhanced nerve root in the favorable VAS group.

Conclusion

Among the variables, MRI showed that the corticosteroid approach for the enhanced target root is the most important prognostic factor in the predicting of the clinical parameters of the favorable TFESIs group.

Citations

Citations to this article as recorded by  
  • The role of facet joint degeneration in the treatment success of transforaminal epidural steroid injection: a retrospective clinical study
    Merve Sekizkardes Tutuncu, Savas Sencan, Canan Bilekyigit Kurt, Serdar Kokar, Osman Hakan Gunduz
    Skeletal Radiology.2025;[Epub]     CrossRef
  • Predictors of successful treatment after transforaminal epidural steroid injections in patients with lumbar disc herniation
    Mustafa Akif Sariyildiz, Ibrahim Batmaz, Salih Hattapoğlu
    Journal of Back and Musculoskeletal Rehabilitation.2024; 37(2): 327.     CrossRef
  • Acute back pain – Role of injection techniques and surgery: WFNS spine committee recommendations
    Nikolay Peev, Corinna Zygourakis, Christoph Sippl, G. Grasso, Joachim Oertel, Salman Sharif
    World Neurosurgery: X.2024; 22: 100315.     CrossRef
  • Clinical Effectiveness of Single Lumbar Periradicular Infiltration in Patients with Sciatica
    Dimitar Veljanovski, Sandra Dejanova Panev, Masha Kostova, Daniela Ristikj-Stomnaroska, Tatjana Deleva Stoshevska, Petar Janevski, Smiljana Bundovska Kocev, Biljana Prgova
    PRILOZI.2023; 44(2): 149.     CrossRef
  • CT-guided transforaminal epidural steroid injection for discogenic lumbar radiculopathy: influence of contrast dispersion and radiologist’s experience on clinical outcome
    Christoph Germann, Dimitri N. Graf, Benjamin Fritz, Reto Sutter
    Skeletal Radiology.2022; 51(4): 783.     CrossRef
  • Predictive value of immediate pain relief after lumbar transforaminal epidural injection with local anesthetics and steroids for single level radiculopathy
    Christoph Germann, Tobias Götschi, Reto Sutter
    Skeletal Radiology.2022; 51(10): 1975.     CrossRef
  • Association of Protein and Genetic Biomarkers With Response to Lumbar Epidural Steroid Injections in Subjects With Axial Low Back Pain
    Stephen Schaaf, Wan Huang, Subashan Perera, Yvette Conley, Inna Belfer, Prakash Jayabalan, Katie Tremont, Paulo Coelho, Sara Ernst, Megan Cortazzo, Debra Weiner, Nam Vo, James Kang, Gwendolyn Sowa
    American Journal of Physical Medicine & Rehabilitation.2021; 100(1): 48.     CrossRef
  • Predictive Factors for the Short-Term Efficacy of Epidural Injections in Lumbar Disc Herniation Treatment
    Jong Seok Baik, Yeong Tae Kim, Dae Jin Nam, Tae Kyun Kim
    Journal of Korean Society of Spine Surgery.2020; 27(4): 138.     CrossRef
  • Cross-sectional CT Assessment of the Extent of Injectate Spread at CT Fluoroscopy–guided Cervical Epidural Interlaminar Steroid Injections
    Timothy J. Amrhein, Erol Bozdogan, Sunit Vekaria, Prasad Patel, Reginald Lerebours, Sheng Luo, Peter G. Kranz
    Radiology.2019; 292(3): 723.     CrossRef
  • 5,806 View
  • 57 Download
  • 10 Web of Science
  • 9 Crossref
The Factors Associated With the Successful Outcomes of Percutaneous Disc Decompression in Patients With Lumbar Herniated Nucleus Pulposus
Sang Heon Lee, Yong Jin Jeong, Nack Hwan Kim, Hyeun Jun Park, Hyun-Joon Yoo, Soo Yung Jo
Ann Rehabil Med 2015;39(5):735-744.   Published online October 26, 2015
DOI: https://doi.org/10.5535/arm.2015.39.5.735
Objective

To determine clinical and radiological factors that predict the successful outcome of percutaneous disc decompression (PDD) in patients with lumbar herniated nucleus pulposus (HNP).

Methods

We retrospectively reviewed the clinical and radiological features of patients who underwent lumbar PDD from April 2009 to March 2013. Sixty-nine patients with lumbar HNP were studied. Clinical outcome was assessed by the visual analogue scale (VAS) and the Oswestry Disability Index (ODI). Multivariate logistic regression analysis was performed to assess relationship among clinical and radiological factors and the successful outcome of the PDD.

Results

The VAS and the ODI decreased significantly at 1 year follow-up (p<0.01). One year after PDD, the reduction of the VAS (ΔVAS) was significantly greater in the patients with pain for <6 months (p=0.03) and subarticular HNP (p=0.015). The reduction of the ODI (ΔODI) was significantly greater in the patients with high intensity zone (p=0.04). Multivariate logistic regression analysis revealed the following 5 factors that were associated with the successful outcome after PDD: pain duration for <6 months (odds ratio [OR]=14.036; p=0.006), positive straight leg raising test (OR=8.425, p=0.014), the extruded HNP (OR=0.106, p=0.04), the sequestrated HNP (OR=0.037, p=0.026), and the subarticular HNP (OR=10.876, p=0.012).

Conclusion

PDD provided significant improvement of pain and disability of patients. The results of the analysis indicated that the duration of pain <6 months, positive straight leg raising test, the subarticular HNP, and the protruded HNP were predicting factors associated with the successful response of PDD in patients with lumbar HNP.

Citations

Citations to this article as recorded by  
  • Obesity and Workers’ Compensation in the Setting of Minimally Invasive Lumbar Decompression
    Madhav R. Patel, Kevin C. Jacob, Michael C. Prabhu, Nisheka N. Vanjani, Hanna Pawlowski, Kanhai Amin, Kern Singh
    World Neurosurgery.2022; 164: e341.     CrossRef
  • Factors Predicting Successful Outcome for Ozone Chemonucleolysis in Lumbar Disk Herniation
    Matteo Luigi Giuseppe Leoni, Annalisa Caruso, Fabrizio Micheli
    Pain Practice.2021; 21(6): 653.     CrossRef
  • Posture control in patients with herniated nucleus pulposus in cervical and lumbosacral spine subjected to operative treatment
    Grzegorz Przysada, Agnieszka Guzik, Izabela Rosak-Matuszewska, Mariusz Drużbicki, Andżelina Wolan-Nieroda, Marek Sobolewski, Justyna Podgórska-Bednarz, Andrzej Maciejczak
    Journal of Back and Musculoskeletal Rehabilitation.2018; 31(5): 795.     CrossRef
  • Aseptic Spondylodiscitis Resulting from Intradiscal Radiofrequency Ablation (IDRA) in Patients with Herniated Disc Disease: A Report of Ten Cases
    Farid Yudoyono, Do Young Kim, Dong Kyu Chin, Dong Ah Shin
    Journal of Minimally Invasive Spine Surgery and Technique.2018; 3(1): 13.     CrossRef
  • 5,914 View
  • 85 Download
  • 3 Web of Science
  • 4 Crossref
Case Reports

Recent years, various percutaneous procedures including cervical nucleoplasty have been developed for disc decompressions to relieve radicular pains caused by disc herniations. We report the application of percutaneous cervical nucleoplasty (PCN) by using the navigable disc decompression device in two patients of cervical herniated intervertebral discs (HIVD). A 38-year-old female diagnosed with C4-C5 disc extrusion with bilateral C5 roots impingement received nucleoplasty twice at C4-C5 disc level. After second procedure, her pain was improved from 6-7/10 to 1-2/10 by visual analog scale (VAS). The second case, a 51-year-male was diagnosed with C6-C7 disc extrusion with right C7 roots impingement and received the procedure at C6-C7 disc level. The pain improved from 8/10 to 3-4/10 by VAS. Successfully, we decompressed cervical herniated discs in 2 HIVD patients without major complications. The PCN with the navigable device will be recommended as an alternative treatment method for cervical HIVD.

Citations

Citations to this article as recorded by  
  • Retrospective Outcome Evaluation of Cervical Nucleoplasty Using Digital Infrared Thermographic Imaging
    Do Hyung Kim, Young Soo Kim, Sang Joon Shin, Hyun Kang, Seokhoon Kim, Hwa Yong Shin
    Neurospine.2019; 16(2): 325.     CrossRef
  • Study of the enzymatic action of the chymopapain using pluronic based nano-carrier system on the cadaveric nucleus pulposus tissue
    Won Il Choi, Gi Yoong Tae, Young Ki Hong
    Journal of the Korea Academia-Industrial cooperation Society.2015; 16(1): 585.     CrossRef
  • 5,860 View
  • 34 Download
  • 2 Crossref
Thoracic Infectious Spondylitis After Surgical Treatments of Herniated Lumbar Intervertebral Disc
Jin-Hyun Kim, Jung-Il Kang, Min Jeong Kim, Seong-Eun Koh, Jongmin Lee, In-Sik Lee, Heeyoune Jung
Ann Rehabil Med 2013;37(5):725-729.   Published online October 29, 2013
DOI: https://doi.org/10.5535/arm.2013.37.5.725

The postoperative infectious spondylitis has been reported to occur among every 1% to 12%. It is difficult to early diagnose in some cases. If the diagnosis is delayed, it can be a life-threatening condition. We report a 32-year-old male patient with postoperative infectious spondylitis. He had surgical treatments for traumatic intervertebral disc herniations in L3-4 and L4-5. Three weeks after surgery, he complained for fever and paraplegia. Cervicothoracic magnetic resonance imaging showed the collapsed T2 and T3 vertebral body with changes of bone marrow signal intensity. Moreover, it showed anterior and posterior epidural masses causing spinal cord compressions which suggested infectious spondylitis. After the use of antibiotics and surgical decompressions T2-T3, his general conditions were improved and muscle power of lower extremities began to be gradually restored. However, we could not identify the exact organisms that may be the cause of infectious spondylitis. It could be important that the infectious spondylitis, which is presented away from the primary operative level, should be observed in patients with fevers of unknown origin and paraplegia.

Citations

Citations to this article as recorded by  
  • Unilateral percutaneous endoscopic debridement and drainage for lumbar infectious spondylitis
    Xuepeng Wang, Shaobo Zhou, Zhenyu Bian, Maoqiang Li, Wu Jiang, Changju Hou, Liulong Zhu
    Journal of Orthopaedic Surgery and Research.2018;[Epub]     CrossRef
  • 5,069 View
  • 38 Download
  • 1 Crossref
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