Method: We retrospectively studied 81 patients with postinfarction seizures to determine the clinical features (onset, type of seizure, etc.) with their clinical recordings, electroencephalographic (EEG), and computed tomographic (CT) or magnetic resonance imaging (MRI) findings.

Results: Patients comprised 49 men and 32 women with their ages ranged from 31 to 87 (mean 64.7) years. After cerebral infarction, 31 patients experienced seizures within 2 weeks and 50 patients more than 2 weeks. Generalized tonic-clonic and simple partial seizures were the most common type of seizure. 40 patients showed focal slowing on EEG. The most common location of the cerebral infarction was cortical area and frequently involved lobes were frontal and temporal lobes. The recurrent seizure was not associated with seizure onset duration, seizure type, EEG finding, or location of infarction. The size of cerebral infarction was significantly associated with recurrent seizure but not associated with first-attack seizure.

Conclusion: This results would be helpful for prevention and treatment of postinfarction seizures. (J Korean Acad Rehab Med 2003; 27: 1-6)

Objective: To investigate the effect of epilepsy and neonatal seizure on development in children with cerebral palsy (CP) or delayed development (DD).

Method: The subjects were 135 patients with CP or DD. Development was evaluated by Bayley Scale of Infant Development II (BSID II). Epilepsy was diagnosed on the base of clinical features, past history and electroencephalography.

Results: The incidence of epilepsy was 18.4% in CP, and 37.8% in DD. Spastic quadriplegia of CP has the highest incidence of epilepsy (38.4%). First seizure attack was occurred before 6 months old of age in 66.7% of CP with epilepsy and in 64.3% of DD with epilepsy. The prevailing type of epilepsy was generalized seizure in DD (57.1%), partial seizure in CP (50.0%). The group with epilepsy had lower psychomotor and mental development quotient on BSID II than the group without epilesy (p＜0.05). Polytherapy was more used to control epilepsy than monotherapy. Valproate (50.0%), phenobarbital (37.5%), carbamazepine (31.3%) were commonly used drugs for controlling epilepsy.

Conclusion: The epilpesy has a negative effect on psychomotor and mental development in the children with CP or DD.