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"Epidural steroid injection"

Original Articles

Efficacy of Epidural Neuroplasty Versus Transforaminal Epidural Steroid Injection for the Radiating Pain Caused by a Herniated Lumbar Disc
Hae Jong Kim, Byeong Cheol Rim, Jeong-Wook Lim, Noh Kyoung Park, Tae-Wook Kang, Min Kyun Sohn, Jaewon Beom, Sangkuk Kang
Ann Rehabil Med 2013;37(6):824-831.   Published online December 23, 2013
DOI: https://doi.org/10.5535/arm.2013.37.6.824
Objective

To compare the treatment effects of epidural neuroplasty (NP) and transforaminal epidural steroid injection (TFESI) for the radiating pain caused by herniated lumbar disc.

Methods

Thirty-two patients diagnosed with herniated lumbar disc through magnetic resonance imaging or computed tomography were included in this study. Fourteen patients received an epidural NP and eighteen patients had a TFESI. The visual analogue scale (VAS) and functional rating index (FRI) were measured before the treatment, and at 2 weeks, 4 weeks and 8 weeks after the treatment.

Results

In the epidural NP group, the mean values of the VAS before the treatment, and at 2 weeks, 4 weeks and 8 weeks after the treatment were 7.00±1.52, 4.29±1.20, 2.64±0.93, 1.43±0.51 and those of FRI were 23.57±3.84, 16.50±3.48, 11.43±2.44, 7.00±2.15. In the TFESI group, the mean values of the VAS before the treatment, and at 2 weeks, 4 weeks and 8 weeks after the treatment were 7.22±2.05, 4.28±1.67, 2.56±1.04, 1.33±0.49 and those of FRI were 22.00±6.64, 16.22±5.07, 11.56±4.18, 8.06±1.89. During the follow-up period, the values of VAS and FRI within each group were significantly reduced (p<0.05) after the treatment. But there were no significant differences between the two groups statistically.

Conclusion

Epidural NP and TFESI are equally effective treatments for the reduction of radiating pain and for improvement of function in patients with a herniated lumbar disc. We recommend that TFESI should be primarily applied to patients who need interventional spine treatment, because it is easier and more cost-effective than epidural NP.

Citations

Citations to this article as recorded by  
  • Effectiveness of intradiscal ozone injections for treating pain following herniated lumbar disc: A systematic review and meta-analysis
    Min Cheol Chang, Yoo Jin Choo, Isabelle Denis, Christopher Mares, Carl Majdalani, Seoyon Yang
    Journal of Back and Musculoskeletal Rehabilitation.2024; 37(5): 1131.     CrossRef
  • Comparison of Clinical Effects and Physical Examination of Transforaminal and Caudal Steroid Injection With Targeted Catheter in Lumbar Radiculopathy: A Single‐Blind Randomized Clinical Trial
    Farnad Imani, Faezeh Mohammad‐Esmaeel, Seyedeh‐Fatemeh Morsalli, Ali Ahani‐Azari, Mahzad Alimian, Nasim Nikoubakht, Azadeh Emami
    Brain and Behavior.2024;[Epub]     CrossRef
  • EVALUATION OF THE EFFICACY OF PERCUTANEOUS CAUDAL AND COMBINED CAUDAL/TRANSFORAMINAL NEUROPLASTY-ADESIOLYSIS FOR TREATING SYMPTOMATIC LUMBAR SPINAL STENOSIS
    Mehmet Osman Akçakaya, Alparslan Aşır, Savaş Çömlek
    Journal of Turkish Spinal Surgery.2023; 34(2): 61.     CrossRef
  • Percutaneous epidural balloon neuroplasty: a narrative review of current evidence
    Doo-Hwan Kim, Jin-Woo Shin, Seong-Soo Choi
    Anesthesia and Pain Medicine.2022; 17(4): 361.     CrossRef
  • Comparison of Clinical Results between Percutaneous Epidural Neuroplasty and Trans-Foraminal Epidural Block for Lumbar Foraminal Stenosis
    Seung-Woo Shim, Min-Young Kim, Young-Jae Kim, Yong-Soo Choi
    Journal of Korean Society of Spine Surgery.2022; 29(4): 107.     CrossRef
  • Nonsurgical treatments for patients with radicular pain from lumbosacral disc herniation
    Jung Hwan Lee, Kyoung Hyo Choi, Seok Kang, Dong Hwan Kim, Du Hwan Kim, Bo Ryun Kim, Won Kim, Jung Hwan Kim, Kyung Hee Do, Jong Geol Do, Ju Seok Ryu, Kyunghoon Min, Sung Gin Bahk, Yun Hee Park, Heui Je Bang, Kyoung-ho Shin, Seoyon Yang, Hee Seung Yang, Seu
    The Spine Journal.2019; 19(9): 1478.     CrossRef
  • Factors Associated with Successful Response to Balloon Decompressive Adhesiolysis Neuroplasty in Patients with Chronic Lumbar Foraminal Stenosis
    Yul Oh, Doo-Hwan Kim, Jun-Young Park, Gyu Yeul Ji, Dong Ah Shin, Sang Won Lee, Jin Kyu Park, Jin-Woo Shin, Seong-Soo Choi
    Journal of Clinical Medicine.2019; 8(11): 1766.     CrossRef
  • The effect of additional transforaminal epidural blocks on percutaneous epidural neuroplasty with a wire-type catheter
    Ho Young Gil, Sook Young Lee, Sang Kee Min, Ji Eun Kim, Hye Seon Lee, Hae Won Jeong, Bumhee Park, Jinhee Choung, Jong Bum Choi
    Medicine.2019; 98(50): e18233.     CrossRef
  • Epidural neuroplasty/epidural adhesiolysis
    Se Hee Kim, Sang Sik Choi
    Anesthesia and Pain Medicine.2016; 11(1): 14.     CrossRef
  • Safety of Epidural Corticosteroid Injections
    Ippokratis Pountos, Michalis Panteli, Gavin Walters, Dudley Bush, Peter V. Giannoudis
    Drugs in R&D.2016; 16(1): 19.     CrossRef
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Efficacy of Transforaminal Epidural Steroid Injections According to Nerve Root Enhancement.
Do, Sung Jin , Ahn, Sang Ho , Cho, Yun Woo , Shim, Dae Seop , Cho, Hee Kyung , Kim, Han Seon , Jang, Sung Ho
J Korean Acad Rehabil Med 2010;34(2):204-208.
Objective
To determine the efficacy of transforaminal epidural steroid injections according to nerve root enhancement in lumbar disc herniations. Method: Twenty seven patients who had extruded or seques tered lumbar disc herniations on enhanced MR imaging were investigated: fifteen patients with corresponding nerve root enhancement (enhanced group), and twelve patients without enhancement (non-enhanced group). All patients received transforaminal epidural steroid injection. Clinical outcomes were measured by visual analogue scale (VAS) for back and radicular pain, Oswestry disability index (ODI) before treatment and one month after injection. Results: The averages of VAS for lower extremity and back pain in both groups one month after injection significantly reduced compared to that of pretreatment, respectively (p<0.001). The amount of decrease in pain in enhanced group was larger than that of non-enhanced group (p<0.05). The averages of ODI in both group one month after injection significantly reduced compared to that of pretreatment (p<0.0001), however, there was no difference between the two groups. Conclusion: The nerve root enhancement on contrast-enhanced MR imaging indicates the presence of severe inflammatory reaction of nerve root, which means well-responsiveness to anti-inflammatory treatment such as transforaminal epidural steroid injection, even if patients' symptom is very severe. (J Korean Acad Rehab Med 2010; 34: 204-208)
  • 2,136 View
  • 17 Download
Objective
To evaluate the outcomes of intensive conservative treatment on extraforaminal lumbar disc herniations. Method: Twenty five patients with extraforaminal lumbar disc herniations with symptomatic radicular pain were included. Under fluoroscopic guidance, 40 mg of triamcinolone was infused around the nerve root after provocation of patient's usual radicular pain. Lumbosacral dynamic stabilization exercise, thermal and electrical therapy, and education of posture correction were added. The clinical outcomes were measured by visual analogue scale (VAS) and Oswestry disability index (ODI) before treatment, one, three, six, and twelve months after the treatment. After twelve months, patients' satisfaction was classified to four categories: excellent, good, fair, or poor. Four patients were dropped out. Results: Follow-up VAS and ODI significantly decreased since post-treatment one month (p<0.0001). The average score of VAS for lower extremity and back pain reduced significantly from 6.6, 4.5 at pretreatment to 1.5, 1.9 at 12 months post-treatment, respectively (p<0.0001). The averages of ODI reduced significantly from 65.4% at pretreatment to 25.4% at post-treatment 12 months (p<0.0001). In patients' satisfaction, seventeen patients (81.0%) were recorded as excellent or good after post-treatment 12 months. Conclusion: Intensive conservative treatment was effective on patients who underwent extraforaminal lumbar disc herniation. Pain relief and functional improvement sustained for 12 months. (J Korean Acad Rehab Med 2009; 33: 89-93)
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Efficacy of Translaminar Epidural Steroid Injection versus Combined Translaminar Epidural Steroid Injection with Selective Nerve Root Injection in Spinal Stenosis.
Nam, Ki Yeon , Ryu, Gi Hyeong , Choi, Jung Min , Choi, Jong Ho , Kwuan, Bum Sun , Park, Jin Woo
J Korean Acad Rehabil Med 2007;31(1):7-13.
Objective
To compare treatment effects of translaminar epidural steroid injections (TLESIs) only and selective nerve root injections (SNRIs) with TLESIs in lumbosacral spinal stenosis. Method: Thirty-four patients diagnosed with magnetic resonance imaging (MRI), somatosensory evoked potential (SEP) and electromyography (EMG) were included. 16 patients who had somatosensory pathway dysfunction or abnormal spontaneous activity received combined SNRIs with TLESIs and 20 patients received only TLESIs. The visual analogue scale (VAS) and functional rating index (FRI) were measured before injection, 1 week and 3 months after 3 times injection. Results: The mean values of VAS before injection, 1 week and 3 months after 3 times injection were 7.55, 3.22, 3.61 in only TLESIs and 7.37, 2.06, 2.31 in SNRIs with TLESIs. The mean values of FRI before injection, 1 week and 3 months after 3 times injection were 25.16, 16.00, 15.83 in only TLESIs and 22.50, 8.37, 8.31 in SNRIs with TLESIs. In the mean values of VAS and FRI were significantly lower SNRIs with TLESIs than only TLESIs (p<0.05). Conclusion: Combined SNRIs with TLESIs were more effective treatment for reduction of pain and improvement of function than only TLESIs in lumbosacral spinal stenosis. (J Korean Acad Rehab Med 2007; 31: 7-13)
  • 1,925 View
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The Change of Blood Glucose and Cortisol Levels after Three Consecutive Epidural Steroid Injections.
Kim, Dong Gun , An, Hyun Mee , Jung, Kyu Young
J Korean Acad Rehabil Med 2006;30(6):590-594.
Objective
To investigate the change of blood glucose and cortisol levels after three consecutive epidural steroid injections Method: Fifteen patients with low back pain and radiating pain were included. Three consecutive epidural injections were performed weekly. The serum glucose, insulin and cortisol levels were measured 30 minutes before the 1st injection and at 24 hours and l week after each injection. Results: There were significant changes in the result of glucose and insulin levels at 24 hours after each injection (p<0.05), but no signigicant changes at 1 week compared with pre-injection level. The cortisol level significantly decreased at 24 hours after 1st injection and did not return to pre-injection level at 1 week after 1st injection (p<0.05). There were no further increases in the glucose and insulin levels and no further decrease in the cortisol level after each of the three consecutive injections. Conclusion: Three consecutive epidural injections at 1 week interval seems to be as safe procedure. But significant suppression of cortisol kept on for 1 week, so it should be taken into account when patients with previous epidural injection undergo major stress. (J Korean Acad Rehab Med 2006; 30: 590-594)
  • 1,947 View
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Effects of L4-5 Transforaminal Epidural Steroid Injection in L5 Radiculopathy.
Ahn, Kyung Hoi , Kim, Hee Sang , Lee, Jong Ha , Kim, Dong Hwan , Cho, Dong Ik , Shin, Ji Cheol , Jeong, Yong Seol
J Korean Acad Rehabil Med 2005;29(3):281-285.
Objective
The aim of this study was to compare the therapeutic and functional values between the L5-S1 transforaminal epidural steroid injection (TFESI) and L4-5 TFESI in patients with L5 radiculopathy. Method: Among 30 patients with unilateral herniated nucleus pulposus (HNP) and L5 radiculopathy, 15 patients received L5-S1 TFESI and 15 patients received L4-5 TFESI. All patients were checked visual analogue scale (VAS) and functional score before injection, after 1 day, 2 weeks and 4 weeks.Results: The VAS of before injection, after 1 day, 2 weeks and 4 weeks were 6.6, 4.0, 3.0, and 2.8 in L5-S1 TFESI, 6.2, 3.9, 2.7, and 2.6 in L4-5 TFESI, respectively. The functional score of before injection, after 1 day, 2 weeks and 4 weeks were 1.8, 2.3, 2.6, and 3.0 in L5-S1 TFESI, 1.6, 2.2, 2.5, and 2.8 in L4-5 TFESI, respectively. There was no statistical difference between the groups (p>0.05). Conclusion: This study suggested that either L5-S1 TFESI or L4-5 TFESI could be a valuable treatment of L5 radicular pain. (J Korean Acad Rehab Med 2005; 29: 281-285)
  • 2,603 View
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Case Report

Epidural Abscess and Pyogenic Arthritis of Knee Joint in One Family after Epidural Injection.
Seo, Jeong Hwan , Kim, Kwan min , Ko, Myoung Hwan
J Korean Acad Rehabil Med 2003;27(3):455-458.
A mother-in-law and a daughter-in-law suffered chronic low back pain and they were injected epidural steroid on same day. Eleven days after injection, the daughter-in-law showed weakness of right lower extremity and lost filling sensation of bladder. Radiologic findings of Magnetic Resonance Imaging for lumbar spine revealed epidural abscess encompassing from L1 to sacral spine. After emergency surgical procedure and antibiotics therapy, the symptoms and the signs disappeared. Seven days after injection, the mother-in- law was diagnosed as pyogenic arthritis of right knee joint and then epidural abscess. Although the surgical procedure for right knee joint and antibiotics therapy were done, the epidural abscess didn't disappear. Moreover, surgical procedure for the epidural abscess couldn't be done due to septic condition, which was the cause of death. We report two cases of epidural abscess showing the importance of early management and serious end result. Prevention of these complication through extreme caution is needed. (J Korean Acad Rehab Med 2003; 27: 455-458)
  • 1,441 View
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Original Article

Effects of Translaminar Approach and Transforaminal Approach in Lumbar Epidural Steroid Injection.
Kim, Hee Sang , Hong, Jang Hyeok , Ahn, Kyung Hoi , Kim, Yong Gul
J Korean Acad Rehabil Med 2000;24(4):733-740.

Objective: The goal of this study was to compare the therapeutic and the functional value between translaminar approach and transforaminal approach of epidural steroid injection in patient with refractory radicular pain.

Method: Among 31 patients with unilateral herniated nucleus pulposus (HNP) which was confirmed by physical examination and magnetic resonance imaging (MRI), 17 patients received a transforaminal approach and 14 patients received a translaminar approach. All patients were evaluated by independent observer and were checked by visual analogue scale (VAS), functional score before and 1 day, 2 weeks and 4 weeks after injection.

Results: The VAS of transforaminal approach was significantly lower than that of translaminar approach after 2 weeks and after 4 weeks (p<0.05), although there were no statistical difference before and 1 day after injection. The functional score of transforaminal approach was significantly higher than that of translaminar approach after 4 weeks (p<0.05), although there were no statistical difference before and 1 day, 2 weeks after injection. The translaminar approach needs more frequent injection (p<0.05).

Conclusion: This study suggests that both translaminar approach and transforaminal approach could be valuable to the initial management of refractory radicular pain, but the duration of therapeutic effects was relatively short in translaminar approach. Transforaminal approach will be the promising treatment of refractory radicular pain, because it has better therapeutic efficacy, safety and longer duration of therapeutic effects than translaminar approach.

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Case Report

Selective Epidural Steroid Injection in a Patient with Refractory Radicular Leg Pain: A case report.
Suh, Jung , Park, Joo Hyun , Sung, Mi Suk , Kang, Sae Yoon , Joa, Kyung Hee , Jang, Young A
J Korean Acad Rehabil Med 2000;24(2):326-331.

For the management of refractory radicular pain, traditional injection techniques such as transcaudal or translumbar epidural steroid injection may be indicated. This epidural injection, done blindly, may result in improper needle placement. Fluoroscopically guided transforaminal epidural steroid injection and computerized tomography-controlled periganglionic foraminal steroid injection are selective nerve blocks. These procedures are useful for the diagnosis. The advantages of these procedures are precise anatomic location provided by fluoroscope or CT.

Intraforaminal or periganglionic steroid injection is useful in the treatment of radicular pain. Thus we introduce a case of selective epidural steroid injection in a patient with refractory radicular pain.

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Original Article
The Outcomes of Epidural Steroid Injection for Treatment of Patients with Spinal Stenosis.
Kim, Hyun Dong , Lee, Kang Woo
J Korean Acad Rehabil Med 1998;22(2):274-281.

The purpose of this study was to see whether there were any correlations between the clinical findings and outcomes after the epidural steroid injection(ESI), and to determine which of the clinical findings might be of importance as favorable signs to predict a good result with the ESI.

The present study involves 23 elderly patients(18 females and 5 males) with spinal stenosis. The participants were divided into several subgroups according to the clinical features, such as presenting symptoms, age, duration of symptoms and physical findings. Subjects received the epidural injection of 80 mg Depo-Medrol with 6 ml of 1.5% lidocaine solution. The subjects completed a questionnaire before the ESI, and at three weeks and two months after the ESI respectively. The questionnaire included three scales on symptom severity, physical function, and satisfaction. The visual analogue pain scale was utilized as well.

At three weeks, satisfaction outcomes were encountered in 82.6 percent of the sudjects. Differences in the satisfaction between the subgroups according to the duration of symptoms and abnormal physical findings were statistically significant(P<0.05). The total scores of symptom severity and physical function had improved from the baseline values(P<0.0001). However, the score changes in each subgroup, for the duration of symptoms differ statistically same (P<0.05) as assessed by the visual analogue pain scale. The results at two months were similar to those of at three weeks. Approximately 78.3% of the patients reported the satisfactory results. Although the follow up period was short, the results demonstrated that the epidural steroid injection afforded much improvement in clinical symptom and physical function in elderly patients with the lumbar spinal stenosis. The only significant difference was the satisfaction outcomes in the groups with short duration of symptoms. The determination of persisting outcomes from the ESI would require a long-term follow-up study.

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