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"Endotracheal intubation"

Case Report
Botulinum Toxin Injection in the Treatment of Postextubation Dysphagia: A Case Report
Byung Wook Kim, Hee-Ju Kim, Jung Keun Hyun, Seo Young Kim, Tae Uk Kim
Ann Rehabil Med 2018;42(2):358-362.   Published online April 30, 2018
DOI: https://doi.org/10.5535/arm.2018.42.2.358

Prolonged intubation is known to bring on postextubation dysphagia (PED) in some patients. We have noted that there were some studies to investigate specific type and pattern of PED, which showed large variety of different swallowing abnormalities as mechanisms of PED that are multifactorial. There are several options of treatment in accordance with the management of these abnormalities. A botulinum toxin (BoT) injection into the upper esophageal sphincter (UES) can improve swallowing functions for patients with this disorder, by working to help the muscle relax. In this case, the conventional treatment was not effective in patients with PED, whereas the BoT injection made a great improvement for these patients. This study suggests that the UES pathology could be the main cause of PED.

Citations

Citations to this article as recorded by  
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    Dysphagia.2026; 41(1): 179.     CrossRef
  • Effect of botulinum toxin injection on cricopharyngeal dysphagia: a systematic review and meta-analysis
    Chao Han, Yongxiang Zhang, Xiaona Pan, Yuanyuan Hou, Yuyang Wang, Hui Sun, Pingping Meng
    Neurological Sciences.2026;[Epub]     CrossRef
  • Botulinum Toxin Injection for the Treatment of Upper Esophageal Sphincter Dysfunction
    Pengxu Wei
    Toxins.2022; 14(5): 321.     CrossRef
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    Zhen Zhang, Sandip K Mishra
    BioMed Research International.2022;[Epub]     CrossRef
  • Ultrasound, electromyography, and balloon guidance for injecting botulinum toxin for cricopharyngeal achalasia
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    Medicine.2021; 100(11): e24909.     CrossRef
  • Exploring the role of botulinum toxin in critical care
    Muhammad Ubaid Hafeez, Michael Moore, Komal Hafeez, Joseph Jankovic
    Expert Review of Neurotherapeutics.2021; 21(8): 881.     CrossRef
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