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"Diffusion tensor MRI"

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"Diffusion tensor MRI"

Case Reports

Terson's Syndrome : A case report.
Kim, Dong hyun , Lee, Ji hun , Jung, Kwang ik , Lee, Jung Ki , Seo, Cheong Hoon , Choi, Eun Hee , Park, Dong Sik , Park, In won , Yoo, Woo kyoung
J Korean Acad Rehabil Med 2006;30(2):184-187.
Terson's syndrome is one of the cerebro-ocular syndrome which entails the findings due to intraocular hemorrhage in association with increased intracranial pressure following subarachnoid hemorrhage. We reported a patient suffering from total blindness after basal ganglia hemorrhage, who was diagnosed as Terson's syndrome and vitrectomy was done. Our patient recovered normal visual acuity after vitrectomy, which fascilitated rehabilitative process. We alsoperformed diffusion tensor tractography to investigate abnormalities of brain related to the visual dysfunction, which revealed decreased orientation and integrity of the right optic radiation. It is important to diagnose Terson's syndrome early because it is one of the cerebro­ocular syndrome which needs early intervention with consideration of the integrity of optic pathway. (J Korean Acad Rehab Med 2006; 30: 184-187)
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We present four pediatric cases examined by diffusion tensor MRI (DTI) to investigate microstructural abnormalities of brain related to their neurologic disability and motor weakness, following absence of any remarkable lesion on the motor pathway in conventional MRI. DTI is a relatively novel MR technique that enables investigation of the orientation and integrity of white matter fiber tracts of the brain in vivo. Case 1, 2 and 3 had suffered from cerebral palsy and case 4 had developed left hemiparesis

after a traumatic brain injury. Conventional brain MRI presented no specific abnormality in case 1 and 2, a focal encephalomalacia in the left anterior thalamus in case 3, and contusional hemorrhages in the left temporal and parietal lobes in case 4. But DTI disclosed microstructural abnormalities on descending motor pathway including the posterior limb of the internal capsule or the cerebral peduncle of the midbrain in all cases. (J Korean Acad Rehab Med 2003; 27: 446-450)

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Original Article
Evidence of Microstructural Abnormality on Descending Motor Pathway in Cerebral Plasied Children with Periventricular Leukomalacia: Diffusion Tensor MRI Study.
Lee, Zee Ihn , Park, Sung Min , Ahn, Sang Ho , Jang, Sung Ho , Son, Su Min , Byun, Woo Mok
J Korean Acad Rehabil Med 2003;27(3):340-343.
Objective
Using diffusion tensor MRI (DTI), to investigate the microstructural abnormality of corticospinal tract in the cerebral palsied children with periventricular leukomalacia on conventional MRI and to recognize the clinical usefulness of DTI.

Method: Seven patients were studied. DTI was peformed using 1.5T MR scanner (Vision Plus, Siemens, Erlangen, Germany) and fractional anisotropies of corona radiata, posterior limbs of internal capsules, and cerebral peduncles of midbrain in both hemisphere were calculated.

Results: The fractional anisotropy was significantly decreased in all corona radiata, posterior limbs of internal capsules, cerebral peduncles of midbrain in six patients except one hemiplegic patient, compared with that of control group. In in the hemiplegic patient, the fractional anisotropy was reduced only in affected hemisphere. In addition, the fractional anisotropy tended to be also increased as gross motor function measure (GMFM) score was increased.

Conclusion: We believe that DTI may be efficient in evaluating microstructural abnormality on the motor pathway of brain and helpful in providing prognosis of clinical findings in cerebral palsied children with periventricular leukomalacia. (J Korean Acad Rehab Med 2003; 27: 340-343)

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