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"Contralateral"

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Physical therapy

Unilateral Vibratory Stimulation Inhibits Contralateral Spinal Anterior Horn Cells in Homonymous Muscles for the First 75 Seconds
Kenta Kunoh, Takahiro Takenaka, Daisuke Kimura, Toshiaki Suzuki
Ann Rehabil Med 2025;49(4):226-233.   Published online August 22, 2025
DOI: https://doi.org/10.5535/arm.240107
Objective
To investigate muscle tone changes over time in contralateral homonymous muscles when unilateral muscles are stimulated, using F-wave measurements, we examined whether vibratory stimulation on the contralateral homonymous muscle of the affected side may reduce spasticity, whose optimal duration remains unclear.
Methods
Vibratory stimulation was applied to the right hand of healthy adults, using parameters of 80 Hz frequency, 0.4 mm amplitude, 400 g load, and 195 seconds of duration on the abductor digiti minimi muscle. F-wave was measured in the left hand before stimulation, at seven intervals during stimulation, and immediately after.
Results
The F/M amplitude ratio decreased immediately at stimulation onset, at 30 seconds, and at 60 seconds compared to baseline. A least-squares analysis revealed a negative slope from baseline to 60 seconds (f(x)=-0.11x+1.12), while the slope became positive after 90 seconds, continuing after stimulation ended (f(x)=0.04x+0.82).
Conclusion
Unilateral vibratory stimulation may decrease excitability in the spinal anterior horn cells of the contralateral homonymous muscle for up to 75 seconds post-stimulation, suggesting a potential mechanism for spasticity management.
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The Mechanism of Contralateral Hyperalgesia in the Persistent Muscle Pain Rat Model.
Sohn, Min Kyun , Kang, Sang Kuk , Lee, Sheng Huo , Han, Sang Min
J Korean Acad Rehabil Med 2004;28(5):477-482.
Objective
This study was designed to investigate the mechanism of the primary afferent input to spread of contralateral hyperalgesia in the persistent muscle pain model in the rat.Method: Muscle pain was induced by twice repeated intramuscular injections of pH 6.0 buffered saline into the unilateral gastrocnemius muscle of the rats. Change of mechanical withdrawal threshold to von-Frey filament was measured after ipsilateral laser irradiation, anesthetic blockade with lidocaine and dorsal rhizotomy (L2∼L6) to reduce primary afferent input from the tissue injury. Results: Bilateral persistent mechanical hyperalgesia in the hind paw was evoked after second injection. Ipsilateral laser irradiation, lidocaine injection and dorsal rhizotomy had no effect on the contralateral spread of mechanical hyperalgesia.Conclusion: These results suggest that contralateral hyperalgesia was produced by, but didn't need to be maintained by inputs from an injury. Therefore, central nervous systems are responsible for the contralateral spread of hyperalgesia. (J Korean Acad Rehab Med 2004; 28: 477-482)
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Cross Training Effect Following Unilateral Leg Strengthening Exercise.
Kim, Jung Tae , Kim, Heon , Bae, Ji Hyae , You, Young Hyun , Park, Young Ok
J Korean Acad Rehabil Med 2000;24(3):527-535.

Objective: To examine the effects of unilateral leg exercise on the contralateral leg and the cross training effect according to the training intensity.

Method: Nineteen healthy males volunteered to be subjects for this investigation and were divided into a training group (N=13) and a control group (N=6). One leg of each subject in the training group was randomly assigned to a six week, three day/week isokinetic strengthening training program for concentric knee extension-flexion performed at 60 degrees/second (group A, N=6) and 180 degrees/second (group B, N=7). The control group did not train for six weeks. The strength of the knee extensor and flexor was tested before and after the six week period training by Cybex 770 dynamometer.

Results: In both groups A and B, the training resulted in significant increase of knee extensor strength in trained limb compared to control group. However, the strength increment of untrained limb was not significant compared to control group.

Conclusion: There was no significant cross training effect following unilateral leg strength exercise.

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Proper Facilitation Technique for Bilateral Motor Evoked Potentials by Transcranial Magnetic Stimulation.
Han, Tai Ryoon , Kim, Jin Ho , Lim, Jae Young
J Korean Acad Rehabil Med 2000;24(1):65-71.

Objective: To identify the existence of ipsilateral responses by magnetic stimulation, and to elucidate the influences of ipsilateral tonic contraction on bilateral MEP responses, and to attain the proper facilitation technique for bilateral MEP responses.

Method: Ten normal healthy volunteers who were right handed, were recruited. They performed the voluntary contraction of thenar muscle via lateral prehension with three stage, contralateral, bilateral, ipsilateral contraction by 70 mm bipolar coil stimulator (figure-of-eight shaped). The excitability threshold (ET) at rest was determined, and then, three facilitation techniques with combination of both voluntary contraction and stimulus intensity were also performed: A technique, minimal facilitation (10% of MVC) with ET intensity; B technique, moderate facilitation (30% of MVC) with 110% of ET intensity; C technique, minimal facilitation (10% of MVC) with 140% of ET intensity. Contralateral, bilateral and ipsilateral voluntary contractions were performed in each technique. In 90 mm circular coil stimulator, same procedure as above was followed.

Results: There were no differences of ET between the two coil stimulators. Ipsilateral MEP responses were not detected after bipolar coil stimulation except one case in C technique, but they were developed over 70% in B and C technique with ipsilateral muscle contraction. However, only 2 cases of ipsilateal responses could be detected in C technique, and not detected in A and B technique. The latency of ipsilateral responses were similar to that of contralateral responses, but the amplitude was much lower than that of contralateral responses. Ipsilateral muscle contraction reduced the amplitude of contralateral MEP in moderate facilitation (B technique). Especially, ipsilateral response was never evoked in B technique with contralateral contraction.

Conclusion: In normal subjects, ipsilateral MEPs can't be obtained in focal magnetic stimulation. Ipsilateral tonic contractions are regarded as reducing facilitative effects of contralateral MEP responses. Bilateral responses should be attained when contralateral target muscle is contracted with moderate facilitation (30% of MVC and 110% of threshold intensity). In this facilitation, the stimulation by circular coil is no less effective than focal stimulation by 70 mm bipolar.

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