Objective To investigate the effect of aqua therapy resistance exercise on arm volume, pain, and shoulder range of movements in post-mastectomy lymphedema.
Methods This was a single-blind randomized controlled trial. Fifty eligible breast cancer survivors (median, 10 years after surgery) with lymphedema (median, 21% inter-limb difference) were assigned randomly to group A (n=25) or control group B (n=25). The study group underwent 60 minutes of aqua therapy exercise comprising of warm-up for 10 minutes, 40 minutes of strengthening exercises, and 10 minutes of cooling down, three times a week for 8 weeks. The control group underwent 60 minutes of land-based exercise three times a week for 8 weeks. Arm volume calculated by measuring the arm circumference, shoulder flexion, and abduction range of motion (ROM), and pain using a visual analog scale (VAS) were assessed at baseline and after 8 weeks of treatment.
Results There was a statistically significant difference in limb volume, shoulder flexion and abduction ROM, and VAS scores in favor of the study group (p<0.001) after 8 weeks of intervention. The mean±standard deviation for limb volume, shoulder flexion, abduction, and pain score were 2,108.71±200.97 mL, 169.68°±4.54°, 150.44°±3.92°, and 3.16±1.1 in the study group and 2,256.41±186.94 mL, 147.36°±5.32°, 131.32°±4.38°, and 5.68±0.94 in the control group, respectively.
Conclusion Adding aqua therapy resistance exercise to routine physical therapy might be more effective in decreasing the limb volume and pain intensity and improving ROM of the shoulder in postmastectomy lymphedema.
Citations
Citations to this article as recorded by
Physical exercise and breast cancer-related lymphedema: an umbrella review, systematic review and meta-analysis Celia García-Chico, Susana López-Ortiz, José Pinto-Fraga, Claudia Ceci, Pedro L. Valenzuela, Saúl Peñín-Grandes, Sergio Maroto-Izquierdo, Grazia Graziani, Carmen Fiuza-Luces, Simone Lista, Alejandro Lucia, Alejandro Santos-Lozano Disability and Rehabilitation.2026; 48(2): 259. CrossRef
From Mobility to Management: A Scoping Review on Exercise in Breast Cancer-Related Lymphedema Cansu Sahbaz Pirincci, Hasan Gercek, Emine Cihan, Elif Dilara Durmaz, Zübeyir Sari Clinical Breast Cancer.2026; 26(1): 114. CrossRef
Physical activity and functional rehabilitation in lower limb soft tissue sarcoma survivors Hawkar A. Nasralla, Rebaz M. Ali, Saywan K. Asaad, Abdullah K. Ghafour, Lawand A. Sharif, Choman S. Omer, Ayoob A. Mohammed, Ali H. Hasan, Fattah H. Fattah, Sherzad W. Mahmood, Ali D. Sadullah, Shvan H. Mohammed, Fahmi H. Kakamad Journal of Medicine, Surgery, and Public Health.2026; 9: 100235. CrossRef
Non-pharmacological therapies for breast cancer-related lymphedema: a systematic review and network meta-analysis based on randomized controlled trials Ningning Fang, Hong Xin, Mengmeng Wu Frontiers in Oncology.2026;[Epub] CrossRef
Effects of Exercise in Adults With Cancer Pain: A Systematic Review and Network Meta-Analysis Jie Wang, Meiling Lv, Hongpeng Li, Dongqing Guo, Xin Chu Journal of Pain and Symptom Management.2025; 69(1): 82. CrossRef
The role of exercise in promoting lymphangiogenesis and extracellular matrix synthesis in lymphedema-induced tissue injury Hong Shik Park, Youngju Song, Joon-Hee Lee, Kyung-Rok Oh, Hyon Park, Hee Kang Molecular Biology Reports.2025;[Epub] CrossRef
Linfedema secundario a cáncer de mama: una revisión narrativa del papel del ejercicio físico Ana Belén Puentes Gutiérrez, Elena Vaquero Ramiro, María García Bascones Revista de Senología y Patología Mamaria.2025; 38(4): 100681. CrossRef
Effects of aquatic exercises in woman who have undergone surgery after breast cancer: a systematic review with meta-analysis Carla T. Silva, Claudia K. Silva, Juliano Casonatto, Aline C. Carrasco, Joseph G. McVeigh, Jefferson R. Cardoso Brazilian Journal of Physical Therapy.2025; 29(5): 101230. CrossRef
Which Physical Therapy Intervention Is Most Effective in Reducing Secondary Lymphedema Associated with Breast Cancer? A Systematic Review and Network Meta-Analysis Raúl Alberto Aguilera-Eguía, Pamela Serón, Ruvistay Gutiérrez-Arias, Brenda Herrera-Serna, Víctor Pérez-Galdavini, Gloria Inostroza-Reyes, Cristian Yáñez-Baeza, Héctor Fuentes-Barría, Hellen Belmar Arriagada, Jaqueline Inostroza-Quiroz, Mariana Melo-Lonco Journal of Clinical Medicine.2025; 14(19): 6762. CrossRef
Methodology of physical rehabilitation for cancer patients following mastectomy Dmitry Sokolov, Natal'ya Fedorova Scientific notes of P. F. Lesgaft University.2025;[Epub] CrossRef
Comparative efficacy of various physical therapies on pain, fatigue, quality of life and functional impairment in breast cancer survivors: a network meta-analysis of randomized controlled trials Yuan Luo, Qi Huang, Xiao Chen, Hongju Peng, Yu Li, Li Chen, Liyue Zhang, Yi Huang Frontiers in Oncology.2025;[Epub] CrossRef
Current Aspects of Medical Rehabilitation of Patients with Cancer Related Lymphedema of Extremities: a Narrative Review Tatiana V. Konchugova, Tatiana V. Apkhanova, Detelina B. Kulchitskaya, Olga V. Yurova, Lev G. Agasarov, Tatyana V. Marfina Bulletin of Rehabilitation Medicine.2024; 23(1): 66. CrossRef
ATUAÇÃO DA FISIOTERAPIA NO LINFEDEMA RELACIONADO AO CÂNCER DE MAMA: REVISÃO INTEGRATIVA Brunna Batista dos Santos, Lívia Alessandra Oliveira, Maria Michely Pereira do Nascimento, Nayara Pinto Gontijo da Silva, Renata Paula de Sousa Santos, Kelly Aline Rodrigues Costa REVISTA FOCO.2024; 17(6): e5424. CrossRef
Effects of different exercise types and cycles on pain and quality of life in breast cancer patients: A systematic review and network meta-analysis Jin Dong, Desheng Wang, Shuai Zhong, Hidetaka Hamasaki PLOS ONE.2024; 19(7): e0300176. CrossRef
Identifying the benefits of recovery programs of aquatic gymnastics, aquatic ludotherapy and therapeutic swimming on human motor, kinetotherapeutic and mental capacity Dana Badau, Adela Badau Heliyon.2024; 10(19): e38690. CrossRef
Water-based exercise for upper and lower limb lymphedema treatment Maria Chiara Maccarone, Erika Venturini, Erica Menegatti, Sergio Gianesini, Stefano Masiero Journal of Vascular Surgery: Venous and Lymphatic Disorders.2023; 11(1): 201. CrossRef
Efectividad de la fisioterapia multimodal acuática mediante ejercicio terapéutico, autodrenaje manual y medidas de autocuidado en el linfedema de miembro superior en mujeres supervivientes de cáncer de mama. Ensayo clínico aleatorizado I. López-Zamora, I. Campos-Varela, S. Muñoz-Castro, A. Justes-Solé, S. Salinas-Huertas, A. Mauri-Aranda Fisioterapia.2023; 45(3): 145. CrossRef
The role of exercise for pain management in adults living with and beyond cancer: a systematic review and meta-analysis Colleen Cuthbert, Rosie Twomey, Mannat Bansal, Benny Rana, Tana Dhruva, Veronica Livingston, Julia T. Daun, S. Nicole Culos-Reed Supportive Care in Cancer.2023;[Epub] CrossRef
Does aquatic physical therapy affect the rehabilitation of breast cancer in women? A systematic review and meta-analysis of randomized controlled trials Juzi Wang, Xiaoyu Chen, Lili Wang, Caiyun Zhang, Ji Ma, Qian Zhao, Mansueto Gomes Neto PLOS ONE.2022; 17(8): e0272337. CrossRef